{"count":2,"next":null,"previous":null,"results":[{"gene_data":{"alias":["HRGP","HPRG"],"biotype":"protein_coding","hgnc_id":"HGNC:5181","gene_name":"histidine rich glycoprotein","omim_gene":["142640"],"alias_name":["histidine-proline rich glycoprotein","thrombophilia due to elevated HRG"],"gene_symbol":"HRG","hgnc_symbol":"HRG","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"3:186378005-186396029","ensembl_id":"ENSG00000113905"}},"GRch38":{"90":{"location":"3:186660216-186678240","ensembl_id":"ENSG00000113905"}}},"hgnc_date_symbol_changed":"1989-05-25"},"entity_type":"gene","entity_name":"HRG","confidence_level":"3","penetrance":"Complete","mode_of_pathogenicity":"","publications":["11057869","9414276","29108964"],"evidence":["Eligibility statement prior genetic testing","Radboud University Medical Center, Nijmegen","Other","Expert Review Green","BRIDGE Study Tier 1 Gene"],"phenotypes":["Histidine-rich glycoprotein deficiency","Thrombophiliadue to elevated HRG","Thrombophilia due to HRG deficiency","Thrombophilia due to elevated HRG 613116","Thrombophilia due to HRG deficiency 613116"],"mode_of_inheritance":"MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown","tags":["missense"],"panel":{"id":175,"hash_id":"5763f32a8f620350a22bccde","name":"Inherited bleeding disorders","disease_group":"Haematological and immunological disorders","disease_sub_group":"Haemostasis disorders","status":"public","version":"1.156","version_created":"2019-08-09T13:55:23.938344Z","relevant_disorders":["Inherited platelet disorders","Monogenic thrombophilia","Inherited bleeding and or platelet disorders","Unprovoked Thrombosis before 40","Monogenic venous thrombosis"],"stats":{"number_of_genes":119,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"}]}},{"gene_data":{"alias":["HRGP","HPRG"],"biotype":"protein_coding","hgnc_id":"HGNC:5181","gene_name":"histidine rich glycoprotein","omim_gene":["142640"],"alias_name":["histidine-proline rich glycoprotein","thrombophilia due to elevated HRG"],"gene_symbol":"HRG","hgnc_symbol":"HRG","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"3:186378005-186396029","ensembl_id":"ENSG00000113905"}},"GRch38":{"90":{"location":"3:186660216-186678240","ensembl_id":"ENSG00000113905"}}},"hgnc_date_symbol_changed":"1989-05-25"},"entity_type":"gene","entity_name":"HRG","confidence_level":"3","penetrance":null,"mode_of_pathogenicity":"","publications":[],"evidence":["North West GLH","Yorkshire and North East GLH","London South GLH","NHS GMS","Expert Review Green","Wessex and West Midlands GLH"],"phenotypes":["613116 Thrombophilia due to HRG deficiency"],"mode_of_inheritance":"MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown","tags":[],"panel":{"id":516,"hash_id":null,"name":"Thrombophilia","disease_group":"","disease_sub_group":"","status":"public","version":"1.0","version_created":"2019-09-23T14:53:24.252789Z","relevant_disorders":["R97"],"stats":{"number_of_genes":20,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"GMS Rare Disease","slug":"gms-rare-disease","description":"This panel type is used for GMS panels that are not virtual (i.e. could be a wet lab test)"},{"name":"GMS signed-off","slug":"gms-signed-off","description":"This panel has undergone review by a NHSE GMS disease specialist group and processes to be signed-off for use within the GMS."}]}}]}