{"count":2,"next":null,"previous":null,"results":[{"gene_data":{"alias":["SF","F-TCF","HGFB","HPTA"],"biotype":"protein_coding","hgnc_id":"HGNC:4893","gene_name":"hepatocyte growth factor","omim_gene":["142409"],"alias_name":["hepatopoietin A","fibroblast-derived tumor cytotoxic factor","scatter factor","lung fibroblast-derived mitogen"],"gene_symbol":"HGF","hgnc_symbol":"HGF","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"7:81328322-81399754","ensembl_id":"ENSG00000019991"}},"GRch38":{"90":{"location":"7:81699006-81770438","ensembl_id":"ENSG00000019991"}}},"hgnc_date_symbol_changed":"1991-06-07"},"entity_type":"gene","entity_name":"HGF","confidence_level":"2","penetrance":"Complete","mode_of_pathogenicity":"Other - please provide details in the comments","publications":["PMID:11343646","11564764","11565020","12574630","1386343","14556002","14691191","1531136","1535333","15545993","17467663","1824873","1831266","1837534","19188684","19576567","2142751","21988987","21988988","22763439","22763448","2528952","2531289","3276728","7624797","7854452","7854453","8804995","8898205","19576567","27610647"],"evidence":["Expert Review Amber","Expert","Radboud University Medical Center, Nijmegen","Emory Genetics Laboratory","UKGTN","Illumina TruGenome Clinical Sequencing Services"],"phenotypes":["Nonsyndromic Hearing Loss, Mixed","Deafness, autosomal recessive 39, 608265"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":["watchlist"],"panel":{"id":126,"hash_id":"558ac48fbb5a16630dcfeaad","name":"Hearing loss","disease_group":"Hearing and ear disorders","disease_sub_group":"Non-syndromic hearing loss","status":"public","version":"2.2","version_created":"2019-09-03T14:01:56.987667Z","relevant_disorders":["Congenital hearing impairment","Autosomal dominant deafness","Congenital hearing impairment (profound/severe)","R67"],"stats":{"number_of_genes":358,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."},{"name":"GMS signed-off","slug":"gms-signed-off","description":"This panel has undergone review by a NHSE GMS disease specialist group and processes to be signed-off for use within the GMS."},{"name":"GMS Rare Disease","slug":"gms-rare-disease","description":"This panel type is used for GMS panels that are not virtual (i.e. could be a wet lab test)"}]}},{"gene_data":{"alias":["SF","F-TCF","HGFB","HPTA"],"biotype":"protein_coding","hgnc_id":"HGNC:4893","gene_name":"hepatocyte growth factor","omim_gene":["142409"],"alias_name":["hepatopoietin A","fibroblast-derived tumor cytotoxic factor","scatter factor","lung fibroblast-derived mitogen"],"gene_symbol":"HGF","hgnc_symbol":"HGF","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"7:81328322-81399754","ensembl_id":"ENSG00000019991"}},"GRch38":{"90":{"location":"7:81699006-81770438","ensembl_id":"ENSG00000019991"}}},"hgnc_date_symbol_changed":"1991-06-07"},"entity_type":"gene","entity_name":"HGF","confidence_level":"1","penetrance":null,"mode_of_pathogenicity":"","publications":["18564920"],"evidence":["Expert list"],"phenotypes":[],"mode_of_inheritance":"Unknown","tags":[],"panel":{"id":65,"hash_id":"57ee82ef8f62035c9b2d0487","name":"Primary lymphoedema","disease_group":"Cardiovascular disorders","disease_sub_group":"Lymphatic Disorders","status":"public","version":"2.0","version_created":"2019-10-02T14:10:33.689992Z","relevant_disorders":["Lymphatic Disorders","Meiges disease","Meige disease","Milroy disease","Lymphoedema distichiasis","Lipoedema disease","R136"],"stats":{"number_of_genes":51,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."},{"name":"GMS signed-off","slug":"gms-signed-off","description":"This panel has undergone review by a NHSE GMS disease specialist group and processes to be signed-off for use within the GMS."}]}}]}