{"count":2,"next":null,"previous":null,"results":[{"gene_data":{"alias":["p532","p619"],"biotype":"protein_coding","hgnc_id":"HGNC:4867","gene_name":"HECT and RLD domain containing E3 ubiquitin protein ligase family member 1","omim_gene":["605109"],"alias_name":null,"gene_symbol":"HERC1","hgnc_symbol":"HERC1","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"15:63900817-64126141","ensembl_id":"ENSG00000103657"}},"GRch38":{"90":{"location":"15:63608618-63833942","ensembl_id":"ENSG00000103657"}}},"hgnc_date_symbol_changed":"1999-01-07"},"entity_type":"gene","entity_name":"HERC1","confidence_level":"1","penetrance":"Complete","mode_of_pathogenicity":"","publications":["26138117","27108999","26153217"],"evidence":["Radboud University Medical Center, Nijmegen","Literature"],"phenotypes":["Macrocephaly, dysmorphic facies, and psychomotor retardation (includes overgrowth phenotype), 617011"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":38,"hash_id":"56fa8eb88f62030f36e3026b","name":"Beckwith-Wiedemann syndrome (BWS) and other congenital overgrowth disorders","disease_group":"Growth disorders","disease_sub_group":"Beckwith-Wiedemann syndrome (BWS) and other congenital overgrowth disorders","status":"public","version":"1.92","version_created":"2019-09-02T14:51:54.105635Z","relevant_disorders":["Atypical Beckwith-Wiedemann syndrome","Classical Beckwith-Wiedemann syndrome","Simpson-Golabi-Behmel syndrome","Sotos syndrome","Weaver syndrome"],"stats":{"number_of_genes":22,"number_of_strs":0,"number_of_regions":1},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"}]}},{"gene_data":{"alias":["p532","p619"],"biotype":"protein_coding","hgnc_id":"HGNC:4867","gene_name":"HECT and RLD domain containing E3 ubiquitin protein ligase family member 1","omim_gene":["605109"],"alias_name":null,"gene_symbol":"HERC1","hgnc_symbol":"HERC1","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"15:63900817-64126141","ensembl_id":"ENSG00000103657"}},"GRch38":{"90":{"location":"15:63608618-63833942","ensembl_id":"ENSG00000103657"}}},"hgnc_date_symbol_changed":"1999-01-07"},"entity_type":"gene","entity_name":"HERC1","confidence_level":"3","penetrance":"Complete","mode_of_pathogenicity":"","publications":["26138117","26153217","27108999"],"evidence":["Expert Review Green","Other"],"phenotypes":["Macrocephaly, dysmorphic facies, and psychomotor retardation 617011"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":285,"hash_id":"558aa423bb5a16630e15b63c","name":"Intellectual disability","disease_group":"Neurology and neurodevelopmental disorders","disease_sub_group":"Neurodevelopmental disorders","status":"public","version":"2.1065","version_created":"2019-10-07T13:42:16.019766Z","relevant_disorders":["Coarse facial features including Coffin-Siris-like disorders","ID","Moderate","severe or profound intellectual disability","Schizophrenia plus additional features","Intellectual disability - microarray","fragile X and sequencing"],"stats":{"number_of_genes":2253,"number_of_strs":11,"number_of_regions":57},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."},{"name":"Component Of Super Panel","slug":"component-of-super-panel","description":"This panel is a component of a Super Panel"}]}}]}