{"count":5,"next":null,"previous":null,"results":[{"gene_data":{"alias":["TFIIE-B","FE","TF2E2"],"biotype":"protein_coding","hgnc_id":"HGNC:4651","gene_name":"general transcription factor IIE subunit 2","omim_gene":["189964"],"alias_name":["TFIIE beta subunit"],"gene_symbol":"GTF2E2","hgnc_symbol":"GTF2E2","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"8:30435835-30515768","ensembl_id":"ENSG00000197265"}},"GRch38":{"90":{"location":"8:30578318-30658251","ensembl_id":"ENSG00000197265"}}},"hgnc_date_symbol_changed":"1993-08-16"},"entity_type":"gene","entity_name":"GTF2E2","confidence_level":"2","penetrance":"Complete","mode_of_pathogenicity":"","publications":["26996949"],"evidence":["Expert Review Amber","Other"],"phenotypes":["Trichothiodystrophy 6, nonphotosensitive","616943"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":77,"hash_id":"5811a8738f620323c5766a2b","name":"Xeroderma pigmentosum, Trichothiodystrophy or Cockayne syndrome","disease_group":"Dysmorphic and congenital abnormality syndromes","disease_sub_group":"DNA repair disorders","status":"public","version":"1.8","version_created":"2019-06-20T15:15:18.560915Z","relevant_disorders":["Cockayne and Xeroderma Pigmentosum-like disorders","Cockayne syndrome","Xeroderma Pigmentosum-like disorders","XP-like disorders"],"stats":{"number_of_genes":17,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease","slug":"gms-rare-disease","description":"This panel type is used for GMS panels that are not virtual (i.e. could be a wet lab test)"}]}},{"gene_data":{"alias":["TFIIE-B","FE","TF2E2"],"biotype":"protein_coding","hgnc_id":"HGNC:4651","gene_name":"general transcription factor IIE subunit 2","omim_gene":["189964"],"alias_name":["TFIIE beta subunit"],"gene_symbol":"GTF2E2","hgnc_symbol":"GTF2E2","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"8:30435835-30515768","ensembl_id":"ENSG00000197265"}},"GRch38":{"90":{"location":"8:30578318-30658251","ensembl_id":"ENSG00000197265"}}},"hgnc_date_symbol_changed":"1993-08-16"},"entity_type":"gene","entity_name":"GTF2E2","confidence_level":"2","penetrance":null,"mode_of_pathogenicity":"","publications":["26996949"],"evidence":["Expert Review Amber"],"phenotypes":["Trichothiodystrophy 6, nonphotosensitive","616943"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":476,"hash_id":null,"name":"White matter disorders and cerebral calcification - narrow panel","disease_group":"","disease_sub_group":"","status":"public","version":"1.9","version_created":"2019-08-08T11:56:25.970239Z","relevant_disorders":[],"stats":{"number_of_genes":191,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"GMS Rare Disease","slug":"gms-rare-disease","description":"This panel type is used for GMS panels that are not virtual (i.e. could be a wet lab test)"},{"name":"Component Of Super Panel","slug":"component-of-super-panel","description":"This panel is a component of a Super Panel"}]}},{"gene_data":{"alias":["TFIIE-B","FE","TF2E2"],"biotype":"protein_coding","hgnc_id":"HGNC:4651","gene_name":"general transcription factor IIE subunit 2","omim_gene":["189964"],"alias_name":["TFIIE beta subunit"],"gene_symbol":"GTF2E2","hgnc_symbol":"GTF2E2","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"8:30435835-30515768","ensembl_id":"ENSG00000197265"}},"GRch38":{"90":{"location":"8:30578318-30658251","ensembl_id":"ENSG00000197265"}}},"hgnc_date_symbol_changed":"1993-08-16"},"entity_type":"gene","entity_name":"GTF2E2","confidence_level":"2","penetrance":null,"mode_of_pathogenicity":"","publications":[],"evidence":["Expert Review Amber","PAGE DD-Gene2Phenotype"],"phenotypes":["DNA Repair-Proficient Trichothiodystrophy"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":478,"hash_id":null,"name":"Fetal anomalies","disease_group":"","disease_sub_group":"","status":"public","version":"0.344","version_created":"2019-09-17T09:38:10.568007Z","relevant_disorders":["R21"],"stats":{"number_of_genes":1721,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."}]}},{"gene_data":{"alias":["TFIIE-B","FE","TF2E2"],"biotype":"protein_coding","hgnc_id":"HGNC:4651","gene_name":"general transcription factor IIE subunit 2","omim_gene":["189964"],"alias_name":["TFIIE beta subunit"],"gene_symbol":"GTF2E2","hgnc_symbol":"GTF2E2","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"8:30435835-30515768","ensembl_id":"ENSG00000197265"}},"GRch38":{"90":{"location":"8:30578318-30658251","ensembl_id":"ENSG00000197265"}}},"hgnc_date_symbol_changed":"1993-08-16"},"entity_type":"gene","entity_name":"GTF2E2","confidence_level":"2","penetrance":null,"mode_of_pathogenicity":"Other - please provide details in the comments","publications":["26996949"],"evidence":["DD-Gene2Phenotype","Expert Review Amber"],"phenotypes":["DNA Repair-Proficient Trichothiodystrophy"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":484,"hash_id":null,"name":"DDG2P","disease_group":"","disease_sub_group":"","status":"public","version":"1.137","version_created":"2019-10-08T15:56:59.220133Z","relevant_disorders":[],"stats":{"number_of_genes":1893,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"GMS Rare Disease","slug":"gms-rare-disease","description":"This panel type is used for GMS panels that are not virtual (i.e. could be a wet lab test)"},{"name":"Component Of Super Panel","slug":"component-of-super-panel","description":"This panel is a component of a Super Panel"}]}},{"gene_data":{"alias":["TFIIE-B","FE","TF2E2"],"biotype":"protein_coding","hgnc_id":"HGNC:4651","gene_name":"general transcription factor IIE subunit 2","omim_gene":["189964"],"alias_name":["TFIIE beta subunit"],"gene_symbol":"GTF2E2","hgnc_symbol":"GTF2E2","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"8:30435835-30515768","ensembl_id":"ENSG00000197265"}},"GRch38":{"90":{"location":"8:30578318-30658251","ensembl_id":"ENSG00000197265"}}},"hgnc_date_symbol_changed":"1993-08-16"},"entity_type":"gene","entity_name":"GTF2E2","confidence_level":"2","penetrance":null,"mode_of_pathogenicity":"","publications":["30914295","26996949"],"evidence":["Expert Review Amber","Literature","Literature"],"phenotypes":["Trichothiodystrophy 6, nonphotosensitive, 616943"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":["watchlist"],"panel":{"id":285,"hash_id":"558aa423bb5a16630e15b63c","name":"Intellectual disability","disease_group":"Neurology and neurodevelopmental disorders","disease_sub_group":"Neurodevelopmental disorders","status":"public","version":"2.1065","version_created":"2019-10-07T13:42:16.019766Z","relevant_disorders":["Coarse facial features including Coffin-Siris-like disorders","ID","Moderate","severe or profound intellectual disability","Schizophrenia plus additional features","Intellectual disability - microarray","fragile X and sequencing"],"stats":{"number_of_genes":2253,"number_of_strs":11,"number_of_regions":57},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."},{"name":"Component Of Super Panel","slug":"component-of-super-panel","description":"This panel is a component of a Super Panel"}]}}]}
