{"count":1,"next":null,"previous":null,"results":[{"gene_data":{"alias":["CD16","CD16a"],"biotype":"protein_coding","hgnc_id":"HGNC:3619","gene_name":"Fc fragment of IgG receptor IIIa","omim_gene":["146740"],"alias_name":["Fc gamma receptor IIIa"],"gene_symbol":"FCGR3A","hgnc_symbol":"FCGR3A","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"1:161511549-161600917","ensembl_id":"ENSG00000203747"}},"GRch38":{"90":{"location":"1:161541759-161550737","ensembl_id":"ENSG00000203747"}}},"hgnc_date_symbol_changed":"1988-11-30"},"entity_type":"gene","entity_name":"FCGR3A","confidence_level":"2","penetrance":null,"mode_of_pathogenicity":null,"publications":["8608639","8874200","23006327","8609432"],"evidence":["Expert Review Amber","IUIS Classification February 2018","Victorian Clinical Genetics Services","ESID Registry 20171117","GRID V2.0"],"phenotypes":["Immunodeficiency 20, 615707","Fc receptor deficiencies","Autosomal recessive primary immunodeficiency with defective spontaneous NK cell cytotoxicity","CD16 deficiency","severe herpes viral infections, particularly VZV, Epstein Barr virus (EBV), and (HPV)","Defects in Intrinsic and Innate Immunity","predisposition to severe viral infection"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":["watchlist"],"panel":{"id":398,"hash_id":null,"name":"Primary immunodeficiency","disease_group":"","disease_sub_group":"","status":"public","version":"1.132","version_created":"2019-09-27T14:37:49.085568Z","relevant_disorders":["Primary immunodeficiency disorders","A- or hypo-gammaglobulinaemia","Congenital neutropaenia","Agranulocytosis","Combined B and T cell defect","Inherited complement deficiency","SCID","Primary immune disorder","Primary immunodeficiency","A-gammaglobulinaemia","Agammaglobulinaemia","hypo-gammaglobulinaemia","hypogammaglobulinemia","immune deficiency syndromes","Severe combined immunodeficiency","Congenital neutopenia","Familial haemophagocytic lymphohistiocytic disorders","Familial hemophagocytic lymphohistiocytic disorders","PID","Sepsis","Disseminated non-tuberculous mycobacterial infection","R15"],"stats":{"number_of_genes":395,"number_of_strs":0,"number_of_regions":2},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."}]}}]}