{"count":4,"next":null,"previous":null,"results":[{"gene_data":{"alias":[],"biotype":"protein_coding","hgnc_id":"HGNC:3115","gene_name":"E2F transcription factor 3","omim_gene":["600427"],"alias_name":null,"gene_symbol":"E2F3","hgnc_symbol":"E2F3","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"6:20402398-20493941","ensembl_id":"ENSG00000112242"}},"GRch38":{"90":{"location":"6:20401906-20493715","ensembl_id":"ENSG00000112242"}}},"hgnc_date_symbol_changed":"1994-08-31"},"entity_type":"gene","entity_name":"E2F3","confidence_level":"1","penetrance":"Complete","mode_of_pathogenicity":"","publications":[],"evidence":["Eligibility statement prior genetic testing"],"phenotypes":[],"mode_of_inheritance":"","tags":[],"panel":{"id":156,"hash_id":"5693974122c1fc251660fb1f","name":"Unexplained kidney failure in young people","disease_group":"Renal and urinary tract disorders","disease_sub_group":"Disorders of function","status":"public","version":"1.73","version_created":"2019-07-17T16:13:42.477129Z","relevant_disorders":["Familial IgA nephropathy and IgA vasculitis","End-stage renal disease - childhood onset"],"stats":{"number_of_genes":166,"number_of_strs":0,"number_of_regions":3},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"}]}},{"gene_data":{"alias":[],"biotype":"protein_coding","hgnc_id":"HGNC:3115","gene_name":"E2F transcription factor 3","omim_gene":["600427"],"alias_name":null,"gene_symbol":"E2F3","hgnc_symbol":"E2F3","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"6:20402398-20493941","ensembl_id":"ENSG00000112242"}},"GRch38":{"90":{"location":"6:20401906-20493715","ensembl_id":"ENSG00000112242"}}},"hgnc_date_symbol_changed":"1994-08-31"},"entity_type":"gene","entity_name":"E2F3","confidence_level":"1","penetrance":null,"mode_of_pathogenicity":"","publications":[],"evidence":["Expert Review Red"],"phenotypes":[],"mode_of_inheritance":"Unknown","tags":[],"panel":{"id":493,"hash_id":null,"name":"Renal and urinary tract disorders","disease_group":"","disease_sub_group":"","status":"public","version":"1.18","version_created":"2019-07-04T13:55:26.963386Z","relevant_disorders":[],"stats":{"number_of_genes":177,"number_of_strs":0,"number_of_regions":3},"types":[{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."}]}},{"gene_data":{"alias":[],"biotype":"protein_coding","hgnc_id":"HGNC:3115","gene_name":"E2F transcription factor 3","omim_gene":["600427"],"alias_name":null,"gene_symbol":"E2F3","hgnc_symbol":"E2F3","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"6:20402398-20493941","ensembl_id":"ENSG00000112242"}},"GRch38":{"90":{"location":"6:20401906-20493715","ensembl_id":"ENSG00000112242"}}},"hgnc_date_symbol_changed":"1994-08-31"},"entity_type":"gene","entity_name":"E2F3","confidence_level":"1","penetrance":null,"mode_of_pathogenicity":"","publications":[],"evidence":["Expert Review Red"],"phenotypes":[],"mode_of_inheritance":"Unknown","tags":[],"panel":{"id":678,"hash_id":null,"name":"Unexplained paediatric onset end-stage renal disease","disease_group":"","disease_sub_group":"","status":"public","version":"0.43","version_created":"2019-09-25T12:25:36.245604Z","relevant_disorders":["R257"],"stats":{"number_of_genes":229,"number_of_strs":0,"number_of_regions":3},"types":[{"name":"GMS Rare Disease","slug":"gms-rare-disease","description":"This panel type is used for GMS panels that are not virtual (i.e. could be a wet lab test)"}]}},{"gene_data":{"alias":[],"biotype":"protein_coding","hgnc_id":"HGNC:3115","gene_name":"E2F transcription factor 3","omim_gene":["600427"],"alias_name":null,"gene_symbol":"E2F3","hgnc_symbol":"E2F3","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"6:20402398-20493941","ensembl_id":"ENSG00000112242"}},"GRch38":{"90":{"location":"6:20401906-20493715","ensembl_id":"ENSG00000112242"}}},"hgnc_date_symbol_changed":"1994-08-31"},"entity_type":"gene","entity_name":"E2F3","confidence_level":"1","penetrance":"Complete","mode_of_pathogenicity":"","publications":["21372519"],"evidence":["NHS GMS","Expert Review Red","Eligibility statement prior genetic testing"],"phenotypes":["FSGS","mental retardation"],"mode_of_inheritance":"","tags":[],"panel":{"id":106,"hash_id":"55af787822c1fc78a829f89f","name":"Proteinuric renal disease","disease_group":"Renal and urinary tract disorders","disease_sub_group":"Syndromes with prominent renal abnormalities","status":"public","version":"1.225","version_created":"2019-10-09T10:57:45.692187Z","relevant_disorders":["R195"],"stats":{"number_of_genes":95,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease","slug":"gms-rare-disease","description":"This panel type is used for GMS panels that are not virtual (i.e. could be a wet lab test)"}]}}]}