{"count":1,"next":null,"previous":null,"results":[{"gene_data":{"alias":[],"biotype":"protein_coding","hgnc_id":"HGNC:32698","gene_name":"dual oxidase maturation factor 2","omim_gene":["612772"],"alias_name":null,"gene_symbol":"DUOXA2","hgnc_symbol":"DUOXA2","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"15:45406519-45410619","ensembl_id":"ENSG00000140274"}},"GRch38":{"90":{"location":"15:45114321-45118421","ensembl_id":"ENSG00000140274"}}},"hgnc_date_symbol_changed":"2006-07-25"},"entity_type":"gene","entity_name":"DUOXA2","confidence_level":"3","penetrance":"Complete","mode_of_pathogenicity":"","publications":["18042646","21367925","28100324","26758695","27349010"],"evidence":["Expert Review Green","Other"],"phenotypes":["Thyroid dyshormonogenesis 5, 274900","HYPOTHYROIDISM, CONGENITAL, DUE TO DYSHORMONOGENESIS, 5","eutopic gland-in-situ","mild congenital hypothyroidism","transient congenital hypothyroidism"],"mode_of_inheritance":"BOTH monoallelic and biallelic, autosomal or pseudoautosomal","tags":["deletions","monogenic-polygenic"],"panel":{"id":31,"hash_id":"5763f2938f620350a1996046","name":"Congenital hypothyroidism","disease_group":"Endocrine disorders","disease_sub_group":"Thyroid disorders","status":"public","version":"2.0","version_created":"2019-07-31T13:52:41.584963Z","relevant_disorders":["Congenital hypothyroidism or thyroid agenesis","R145"],"stats":{"number_of_genes":34,"number_of_strs":0,"number_of_regions":2},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."},{"name":"GMS signed-off","slug":"gms-signed-off","description":"This panel has undergone review by a NHSE GMS disease specialist group and processes to be signed-off for use within the GMS."}]}}]}