{"count":2,"next":null,"previous":null,"results":[{"gene_data":{"alias":[],"biotype":"protein_coding","hgnc_id":"HGNC:2916","gene_name":"distal-less homeobox 3","omim_gene":["600525"],"alias_name":null,"gene_symbol":"DLX3","hgnc_symbol":"DLX3","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"17:48067369-48072588","ensembl_id":"ENSG00000064195"}},"GRch38":{"90":{"location":"17:49990005-49995224","ensembl_id":"ENSG00000064195"}}},"hgnc_date_symbol_changed":"1995-05-16"},"entity_type":"gene","entity_name":"DLX3","confidence_level":"3","penetrance":"Complete","mode_of_pathogenicity":"","publications":["26104267","26762616"],"evidence":["NHS GMS","Expert Review Green","UKGTN","Emory Genetics Laboratory","Radboud University Medical Center, Nijmegen","Expert list",""],"phenotypes":["Amelogenesis imperfecta, type IV 104510","Trichodontoosseous syndrome 190320"],"mode_of_inheritance":"MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","tags":[],"panel":{"id":309,"hash_id":"5693952f22c1fc251660fb1e","name":"Skeletal dysplasia","disease_group":"Skeletal disorders","disease_sub_group":"Skeletal dysplasias","status":"public","version":"1.203","version_created":"2019-10-03T09:38:50.417968Z","relevant_disorders":["Unexplained skeletal dysplasia","Skeletal dysplasia"],"stats":{"number_of_genes":546,"number_of_strs":1,"number_of_regions":6},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."},{"name":"Component Of Super Panel","slug":"component-of-super-panel","description":"This panel is a component of a Super Panel"}]}},{"gene_data":{"alias":[],"biotype":"protein_coding","hgnc_id":"HGNC:2916","gene_name":"distal-less homeobox 3","omim_gene":["600525"],"alias_name":null,"gene_symbol":"DLX3","hgnc_symbol":"DLX3","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"17:48067369-48072588","ensembl_id":"ENSG00000064195"}},"GRch38":{"90":{"location":"17:49990005-49995224","ensembl_id":"ENSG00000064195"}}},"hgnc_date_symbol_changed":"1995-05-16"},"entity_type":"gene","entity_name":"DLX3","confidence_level":"3","penetrance":"Complete","mode_of_pathogenicity":"","publications":["21252474","20151948","26104267","15666299","9467018","23949819"],"evidence":["Expert Review Green","Illumina TruGenome Clinical Sequencing Services","UKGTN","Radboud University Medical Center, Nijmegen","Eligibility statement prior genetic testing"],"phenotypes":["Amelogenesis imperfecta, type IV, 104510","Amelogenesis Imperfecta, Type IV, 104510","Amelogenesis Imperfecta, Dominant","amelogenesis imperfecta with taurodontism","Trichodontoosseous syndrome, 190320","Tricho-dento-osseous syndrome (TDO) (includes enamel hypoplasia)","hypoplastic AI, taurodontism and kinky hair","Tricho-Dento-Osseous syndrome , Amelogenesis Imperfecta, hypoplastic"],"mode_of_inheritance":"MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted","tags":[],"panel":{"id":269,"hash_id":"58c7f3c78f620328d77ce70e","name":"Amelogenesis imperfecta","disease_group":"Skeletal disorders","disease_sub_group":"Skeletal dysplasias","status":"public","version":"2.0","version_created":"2019-09-04T13:55:51.137280Z","relevant_disorders":["Amelogenesis Imperfecta","R340"],"stats":{"number_of_genes":39,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease","slug":"gms-rare-disease","description":"This panel type is used for GMS panels that are not virtual (i.e. could be a wet lab test)"},{"name":"GMS signed-off","slug":"gms-signed-off","description":"This panel has undergone review by a NHSE GMS disease specialist group and processes to be signed-off for use within the GMS."}]}}]}