{"count":3,"next":null,"previous":null,"results":[{"gene_data":{"alias":["HHG-3","MGC35145"],"biotype":"protein_coding","hgnc_id":"HGNC:2865","gene_name":"desert hedgehog","omim_gene":["605423"],"alias_name":null,"gene_symbol":"DHH","hgnc_symbol":"DHH","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"12:49483204-49488602","ensembl_id":"ENSG00000139549"}},"GRch38":{"90":{"location":"12:49089421-49094819","ensembl_id":"ENSG00000139549"}}},"hgnc_date_symbol_changed":"2000-04-28"},"entity_type":"gene","entity_name":"DHH","confidence_level":"3","penetrance":"Complete","mode_of_pathogenicity":"","publications":["25927242","23786321","21816240"],"evidence":["Expert Review Green","UKGTN","Illumina TruGenome Clinical Sequencing Services","Other","Radboud University Medical Center, Nijmegen","Emory Genetics Laboratory"],"phenotypes":["46XY partial gonadal dysgenesis, with minifascicular neuropathy, 607080","46XY sex reversal 7, 233420"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":9,"hash_id":"569380ac22c1fc251660faf8","name":"Disorders of sex development","disease_group":"Endocrine disorders","disease_sub_group":"Gonadal and sex development disorders","status":"public","version":"2.1","version_created":"2019-10-01T10:16:03.440399Z","relevant_disorders":["R146"],"stats":{"number_of_genes":54,"number_of_strs":0,"number_of_regions":1},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."},{"name":"GMS signed-off","slug":"gms-signed-off","description":"This panel has undergone review by a NHSE GMS disease specialist group and processes to be signed-off for use within the GMS."}]}},{"gene_data":{"alias":["HHG-3","MGC35145"],"biotype":"protein_coding","hgnc_id":"HGNC:2865","gene_name":"desert hedgehog","omim_gene":["605423"],"alias_name":null,"gene_symbol":"DHH","hgnc_symbol":"DHH","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"12:49483204-49488602","ensembl_id":"ENSG00000139549"}},"GRch38":{"90":{"location":"12:49089421-49094819","ensembl_id":"ENSG00000139549"}}},"hgnc_date_symbol_changed":"2000-04-28"},"entity_type":"gene","entity_name":"DHH","confidence_level":"1","penetrance":null,"mode_of_pathogenicity":"","publications":[],"evidence":["Expert Review Red","PAGE Additional Gene List"],"phenotypes":["46XY partial gonadal dysgenesis, with minifascicular neuropathy","46XY sex reversal 7"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":478,"hash_id":null,"name":"Fetal anomalies","disease_group":"","disease_sub_group":"","status":"public","version":"0.344","version_created":"2019-09-17T09:38:10.568007Z","relevant_disorders":["R21"],"stats":{"number_of_genes":1721,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."}]}},{"gene_data":{"alias":["HHG-3","MGC35145"],"biotype":"protein_coding","hgnc_id":"HGNC:2865","gene_name":"desert hedgehog","omim_gene":["605423"],"alias_name":null,"gene_symbol":"DHH","hgnc_symbol":"DHH","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"12:49483204-49488602","ensembl_id":"ENSG00000139549"}},"GRch38":{"90":{"location":"12:49089421-49094819","ensembl_id":"ENSG00000139549"}}},"hgnc_date_symbol_changed":"2000-04-28"},"entity_type":"gene","entity_name":"DHH","confidence_level":"1","penetrance":"Complete","mode_of_pathogenicity":"","publications":[],"evidence":["NHS GMS","South West GLH","UKGTN"],"phenotypes":[],"mode_of_inheritance":"","tags":[],"panel":{"id":85,"hash_id":"55ad205422c1fc7041340234","name":"Hereditary neuropathy","disease_group":"Neurology and neurodevelopmental disorders","disease_sub_group":"Motor and Sensory Disorders of the PNS","status":"public","version":"1.333","version_created":"2019-07-09T13:10:50.031506Z","relevant_disorders":["Charcot-Marie-Tooth disease"],"stats":{"number_of_genes":276,"number_of_strs":11,"number_of_regions":2},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."}]}}]}