{"count":5,"next":null,"previous":null,"results":[{"gene_data":{"alias":["FLJ39501"],"biotype":"protein_coding","hgnc_id":"HGNC:26820","gene_name":"cytochrome P450 family 4 subfamily F member 22","omim_gene":["611495"],"alias_name":null,"gene_symbol":"CYP4F22","hgnc_symbol":"CYP4F22","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"19:15619304-15663128","ensembl_id":"ENSG00000171954"}},"GRch38":{"90":{"location":"19:15508493-15552317","ensembl_id":"ENSG00000171954"}}},"hgnc_date_symbol_changed":"2007-05-18"},"entity_type":"gene","entity_name":"CYP4F22","confidence_level":"1","penetrance":"Complete","mode_of_pathogenicity":"","publications":[],"evidence":["Expert Review Red","Other"],"phenotypes":["Ichthyosis, congenital, autosomal recessive 5, 604777","Lamellar ichthyosis","Some affected persons exhibit scarring alopecia"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":305,"hash_id":"568e844522c1fc1c78b67156","name":"Familial cicatricial alopecia","disease_group":"Dermatological disorders","disease_sub_group":"Skin adnexa disorders","status":"public","version":"1.2","version_created":"2019-06-20T15:15:02.358694Z","relevant_disorders":[],"stats":{"number_of_genes":25,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"}]}},{"gene_data":{"alias":["FLJ39501"],"biotype":"protein_coding","hgnc_id":"HGNC:26820","gene_name":"cytochrome P450 family 4 subfamily F member 22","omim_gene":["611495"],"alias_name":null,"gene_symbol":"CYP4F22","hgnc_symbol":"CYP4F22","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"19:15619304-15663128","ensembl_id":"ENSG00000171954"}},"GRch38":{"90":{"location":"19:15508493-15552317","ensembl_id":"ENSG00000171954"}}},"hgnc_date_symbol_changed":"2007-05-18"},"entity_type":"gene","entity_name":"CYP4F22","confidence_level":"3","penetrance":"Complete","mode_of_pathogenicity":"","publications":[],"evidence":["Expert Review Green","UKGTN","Illumina TruGenome Clinical Sequencing Services","Radboud University Medical Center, Nijmegen","Eligibility statement prior genetic testing"],"phenotypes":["Ichthyosis, congenital, autosomal recessive 5, 604777"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":282,"hash_id":"562e5d2622c1fc582756e3b5","name":"Autosomal recessive congenital ichthyosis","disease_group":"Dermatological disorders","disease_sub_group":"Ichthyoses","status":"public","version":"1.9","version_created":"2019-06-20T15:14:56.521067Z","relevant_disorders":[],"stats":{"number_of_genes":14,"number_of_strs":0,"number_of_regions":1},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"}]}},{"gene_data":{"alias":["FLJ39501"],"biotype":"protein_coding","hgnc_id":"HGNC:26820","gene_name":"cytochrome P450 family 4 subfamily F member 22","omim_gene":["611495"],"alias_name":null,"gene_symbol":"CYP4F22","hgnc_symbol":"CYP4F22","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"19:15619304-15663128","ensembl_id":"ENSG00000171954"}},"GRch38":{"90":{"location":"19:15508493-15552317","ensembl_id":"ENSG00000171954"}}},"hgnc_date_symbol_changed":"2007-05-18"},"entity_type":"gene","entity_name":"CYP4F22","confidence_level":"3","penetrance":null,"mode_of_pathogenicity":"","publications":[],"evidence":["Expert Review Green"],"phenotypes":["Ichthyosis, congenital, autosomal recessive 5, 604777"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":555,"hash_id":null,"name":"Ichthyosis and erythrokeratoderma","disease_group":"","disease_sub_group":"","status":"public","version":"0.10","version_created":"2019-09-09T15:38:37.080974Z","relevant_disorders":[],"stats":{"number_of_genes":64,"number_of_strs":0,"number_of_regions":1},"types":[{"name":"GMS Rare Disease","slug":"gms-rare-disease","description":"This panel type is used for GMS panels that are not virtual (i.e. could be a wet lab test)"},{"name":"Component Of Super Panel","slug":"component-of-super-panel","description":"This panel is a component of a Super Panel"}]}},{"gene_data":{"alias":["FLJ39501"],"biotype":"protein_coding","hgnc_id":"HGNC:26820","gene_name":"cytochrome P450 family 4 subfamily F member 22","omim_gene":["611495"],"alias_name":null,"gene_symbol":"CYP4F22","hgnc_symbol":"CYP4F22","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"19:15619304-15663128","ensembl_id":"ENSG00000171954"}},"GRch38":{"90":{"location":"19:15508493-15552317","ensembl_id":"ENSG00000171954"}}},"hgnc_date_symbol_changed":"2007-05-18"},"entity_type":"gene","entity_name":"CYP4F22","confidence_level":"1","penetrance":null,"mode_of_pathogenicity":"","publications":[],"evidence":["Expert Review Red"],"phenotypes":["Some affected persons exhibit scarring alopecia","Lamellar ichthyosis","Ichthyosis, congenital, autosomal recessive 5, 604777"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":553,"hash_id":null,"name":"Ectodermal dysplasia","disease_group":"","disease_sub_group":"","status":"public","version":"0.22","version_created":"2019-09-17T19:00:33.930109Z","relevant_disorders":[],"stats":{"number_of_genes":71,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"GMS Rare Disease","slug":"gms-rare-disease","description":"This panel type is used for GMS panels that are not virtual (i.e. could be a wet lab test)"},{"name":"Component Of Super Panel","slug":"component-of-super-panel","description":"This panel is a component of a Super Panel"}]}},{"gene_data":{"alias":["FLJ39501"],"biotype":"protein_coding","hgnc_id":"HGNC:26820","gene_name":"cytochrome P450 family 4 subfamily F member 22","omim_gene":["611495"],"alias_name":null,"gene_symbol":"CYP4F22","hgnc_symbol":"CYP4F22","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"19:15619304-15663128","ensembl_id":"ENSG00000171954"}},"GRch38":{"90":{"location":"19:15508493-15552317","ensembl_id":"ENSG00000171954"}}},"hgnc_date_symbol_changed":"2007-05-18"},"entity_type":"gene","entity_name":"CYP4F22","confidence_level":"3","penetrance":null,"mode_of_pathogenicity":"","publications":[],"evidence":["London North GLH","NHS GMS","Expert Review Green"],"phenotypes":["Autosomal recessive congenital ichthyosis"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":556,"hash_id":null,"name":"Palmoplantar keratodermas","disease_group":"","disease_sub_group":"","status":"public","version":"0.9","version_created":"2019-09-09T15:38:38.871976Z","relevant_disorders":[],"stats":{"number_of_genes":69,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"GMS Rare Disease","slug":"gms-rare-disease","description":"This panel type is used for GMS panels that are not virtual (i.e. could be a wet lab test)"},{"name":"Component Of Super Panel","slug":"component-of-super-panel","description":"This panel is a component of a Super Panel"}]}}]}