{"count":3,"next":null,"previous":null,"results":[{"gene_data":{"alias":["RAIDD"],"biotype":"protein_coding","hgnc_id":"HGNC:2340","gene_name":"CASP2 and RIPK1 domain containing adaptor with death domain","omim_gene":["603454"],"alias_name":["RIP-associated ICH1/CED3-homologous protein with death domain"],"gene_symbol":"CRADD","hgnc_symbol":"CRADD","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"12:94071151-94288616","ensembl_id":"ENSG00000169372"}},"GRch38":{"90":{"location":"12:93677375-93894840","ensembl_id":"ENSG00000169372"}}},"hgnc_date_symbol_changed":"1999-05-07"},"entity_type":"gene","entity_name":"CRADD","confidence_level":"2","penetrance":null,"mode_of_pathogenicity":"","publications":[],"evidence":["Expert Review Amber","PAGE DD-Gene2Phenotype"],"phenotypes":["Megalencephaly with Variant Lissencephaly"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":478,"hash_id":null,"name":"Fetal anomalies","disease_group":"","disease_sub_group":"","status":"public","version":"0.344","version_created":"2019-09-17T09:38:10.568007Z","relevant_disorders":["R21"],"stats":{"number_of_genes":1721,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."}]}},{"gene_data":{"alias":["RAIDD"],"biotype":"protein_coding","hgnc_id":"HGNC:2340","gene_name":"CASP2 and RIPK1 domain containing adaptor with death domain","omim_gene":["603454"],"alias_name":["RIP-associated ICH1/CED3-homologous protein with death domain"],"gene_symbol":"CRADD","hgnc_symbol":"CRADD","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"12:94071151-94288616","ensembl_id":"ENSG00000169372"}},"GRch38":{"90":{"location":"12:93677375-93894840","ensembl_id":"ENSG00000169372"}}},"hgnc_date_symbol_changed":"1999-05-07"},"entity_type":"gene","entity_name":"CRADD","confidence_level":"2","penetrance":null,"mode_of_pathogenicity":"Other - please provide details in the comments","publications":["27773430"],"evidence":["DD-Gene2Phenotype","Expert Review Amber"],"phenotypes":["Megalencephaly with Variant Lissencephaly","MENTAL RETARDATION, NON-SYNDROMIC 614499"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":["watchlist"],"panel":{"id":484,"hash_id":null,"name":"DDG2P","disease_group":"","disease_sub_group":"","status":"public","version":"1.137","version_created":"2019-10-08T15:56:59.220133Z","relevant_disorders":[],"stats":{"number_of_genes":1893,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"GMS Rare Disease","slug":"gms-rare-disease","description":"This panel type is used for GMS panels that are not virtual (i.e. could be a wet lab test)"},{"name":"Component Of Super Panel","slug":"component-of-super-panel","description":"This panel is a component of a Super Panel"}]}},{"gene_data":{"alias":["RAIDD"],"biotype":"protein_coding","hgnc_id":"HGNC:2340","gene_name":"CASP2 and RIPK1 domain containing adaptor with death domain","omim_gene":["603454"],"alias_name":["RIP-associated ICH1/CED3-homologous protein with death domain"],"gene_symbol":"CRADD","hgnc_symbol":"CRADD","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"12:94071151-94288616","ensembl_id":"ENSG00000169372"}},"GRch38":{"90":{"location":"12:93677375-93894840","ensembl_id":"ENSG00000169372"}}},"hgnc_date_symbol_changed":"1999-05-07"},"entity_type":"gene","entity_name":"CRADD","confidence_level":"3","penetrance":"Complete","mode_of_pathogenicity":"","publications":["22279524","27773430"],"evidence":["Victorian Clinical Genetics Services","Expert Review Green","Expert Review Green","Expert Review Red"],"phenotypes":["Mental retardation, autosomal recessive 34, with variant lissencephaly  614499"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":285,"hash_id":"558aa423bb5a16630e15b63c","name":"Intellectual disability","disease_group":"Neurology and neurodevelopmental disorders","disease_sub_group":"Neurodevelopmental disorders","status":"public","version":"2.1065","version_created":"2019-10-07T13:42:16.019766Z","relevant_disorders":["Coarse facial features including Coffin-Siris-like disorders","ID","Moderate","severe or profound intellectual disability","Schizophrenia plus additional features","Intellectual disability - microarray","fragile X and sequencing"],"stats":{"number_of_genes":2253,"number_of_strs":11,"number_of_regions":57},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."},{"name":"Component Of Super Panel","slug":"component-of-super-panel","description":"This panel is a component of a Super Panel"}]}}]}