{"count":2,"next":null,"previous":null,"results":[{"gene_data":{"alias":["HCORO1","p57","coronin-1"],"biotype":"protein_coding","hgnc_id":"HGNC:2252","gene_name":"coronin 1A","omim_gene":["605000"],"alias_name":["Clabp TACO"],"gene_symbol":"CORO1A","hgnc_symbol":"CORO1A","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"16:30194148-30200397","ensembl_id":"ENSG00000102879"}},"GRch38":{"90":{"location":"16:30182827-30189076","ensembl_id":"ENSG00000102879"}}},"hgnc_date_symbol_changed":"1999-10-19"},"entity_type":"gene","entity_name":"CORO1A","confidence_level":"2","penetrance":null,"mode_of_pathogenicity":"","publications":[],"evidence":["Expert Review Amber"],"phenotypes":[],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":562,"hash_id":null,"name":"Epidermodysplasia verruciformis","disease_group":"","disease_sub_group":"","status":"public","version":"0.9","version_created":"2019-09-09T15:38:35.409460Z","relevant_disorders":[],"stats":{"number_of_genes":7,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"GMS Rare Disease","slug":"gms-rare-disease","description":"This panel type is used for GMS panels that are not virtual (i.e. could be a wet lab test)"},{"name":"Component Of Super Panel","slug":"component-of-super-panel","description":"This panel is a component of a Super Panel"}]}},{"gene_data":{"alias":["HCORO1","p57","coronin-1"],"biotype":"protein_coding","hgnc_id":"HGNC:2252","gene_name":"coronin 1A","omim_gene":["605000"],"alias_name":["Clabp TACO"],"gene_symbol":"CORO1A","hgnc_symbol":"CORO1A","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"16:30194148-30200397","ensembl_id":"ENSG00000102879"}},"GRch38":{"90":{"location":"16:30182827-30189076","ensembl_id":"ENSG00000102879"}}},"hgnc_date_symbol_changed":"1999-10-19"},"entity_type":"gene","entity_name":"CORO1A","confidence_level":"3","penetrance":null,"mode_of_pathogenicity":null,"publications":["23522482","18836449","19097825"],"evidence":["NHS GMS","North West GLH","London North GLH","IUIS Classification February 2018","Victorian Clinical Genetics Services","Expert Review Green","ESID Registry 20171117","GRID V2.0","GOSH PID v.8.0","Combined B and T cell defect v1.12"],"phenotypes":["Immunodeficiency 8","Combined immunodeficiency","hypogammaglobulinaemia, combined immunodeficiency","Coronin-1A deficiency","Atypical Severe Combined Immunodeficiency (Atypical SCID)","Severe combined immunodeficiency (SCID)","Omenn syndrome","Detectable thymus, EBV","Immunodeficiencies affecting cellular and humoral immunity"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":398,"hash_id":null,"name":"Primary immunodeficiency","disease_group":"","disease_sub_group":"","status":"public","version":"1.132","version_created":"2019-09-27T14:37:49.085568Z","relevant_disorders":["Primary immunodeficiency disorders","A- or hypo-gammaglobulinaemia","Congenital neutropaenia","Agranulocytosis","Combined B and T cell defect","Inherited complement deficiency","SCID","Primary immune disorder","Primary immunodeficiency","A-gammaglobulinaemia","Agammaglobulinaemia","hypo-gammaglobulinaemia","hypogammaglobulinemia","immune deficiency syndromes","Severe combined immunodeficiency","Congenital neutopenia","Familial haemophagocytic lymphohistiocytic disorders","Familial hemophagocytic lymphohistiocytic disorders","PID","Sepsis","Disseminated non-tuberculous mycobacterial infection","R15"],"stats":{"number_of_genes":395,"number_of_strs":0,"number_of_regions":2},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."}]}}]}