{"count":2,"next":null,"previous":null,"results":[{"gene_data":{"alias":["HH114","MGC11326","FLJ22851"],"biotype":"protein_coding","hgnc_id":"HGNC:26929","gene_name":"chromosome 15 open reading frame 41","omim_gene":["615626"],"alias_name":null,"gene_symbol":"C15orf41","hgnc_symbol":"C15orf41","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"15:36871812-37102449","ensembl_id":"ENSG00000186073"}},"GRch38":{"90":{"location":"15:36579611-36810248","ensembl_id":"ENSG00000186073"}}},"hgnc_date_symbol_changed":"2005-10-24"},"entity_type":"gene","entity_name":"C15orf41","confidence_level":"3","penetrance":"Complete","mode_of_pathogenicity":"Other - please provide details in the comments","publications":["23716552","16643452","9220189"],"evidence":["Expert Review Green","Eligibility statement prior genetic testing","UKGTN"],"phenotypes":["Congenital Dyserythropoietic Anemia","Dyserythropoietic anemia, congenital, type Ib 615631"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":["missense"],"panel":{"id":159,"hash_id":"58a70e858f62037e8779b2e8","name":"Cytopenias and congenital anaemias","disease_group":"Haematological disorders","disease_sub_group":"Anaemias and red cell disorders","status":"public","version":"1.73","version_created":"2019-09-23T11:25:32.403071Z","relevant_disorders":["Aplastic anaemia with or without paroxysmal nocturnal haemoglobinuria","Apparent aplastic anaemia or paroxysmal nocturnal haemoglobinuria","Congenital anaemias","Early onset pancytopenia and red cell disorders","Anaemias and red cell disorders","Cytopaenias and congenital anaemias","Cytopenia and pancytopenia"],"stats":{"number_of_genes":219,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"}]}},{"gene_data":{"alias":["HH114","MGC11326","FLJ22851"],"biotype":"protein_coding","hgnc_id":"HGNC:26929","gene_name":"chromosome 15 open reading frame 41","omim_gene":["615626"],"alias_name":null,"gene_symbol":"C15orf41","hgnc_symbol":"C15orf41","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"15:36871812-37102449","ensembl_id":"ENSG00000186073"}},"GRch38":{"90":{"location":"15:36579611-36810248","ensembl_id":"ENSG00000186073"}}},"hgnc_date_symbol_changed":"2005-10-24"},"entity_type":"gene","entity_name":"C15orf41","confidence_level":"3","penetrance":null,"mode_of_pathogenicity":"","publications":["23716552","29031773","29885034"],"evidence":["North West GLH","Yorkshire and North East GLH","London South GLH","NHS GMS","Expert Review Green","Wessex and West Midlands GLH"],"phenotypes":["Dyserythropoietic anemia, congenital, type Ib","615631 Congenital dyserythropoietic anaemia type 1b","615631 Congenital Dyserythropoietic Anemia","Congenital Dyserythropoietic Anemia","Dyserythropoietic anemia, congenital, type Ib, 615631"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":518,"hash_id":null,"name":"Rare anaemia","disease_group":"","disease_sub_group":"","status":"public","version":"1.0","version_created":"2019-09-23T14:44:13.433190Z","relevant_disorders":["R92"],"stats":{"number_of_genes":94,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"GMS Rare Disease","slug":"gms-rare-disease","description":"This panel type is used for GMS panels that are not virtual (i.e. could be a wet lab test)"},{"name":"GMS signed-off","slug":"gms-signed-off","description":"This panel has undergone review by a NHSE GMS disease specialist group and processes to be signed-off for use within the GMS."}]}}]}