{"count":2,"next":null,"previous":null,"results":[{"gene_data":{"alias":["CTIP-2","CTIP2","hRIT1-alpha"],"biotype":"protein_coding","hgnc_id":"HGNC:13222","gene_name":"B-cell CLL/lymphoma 11B","omim_gene":["606558"],"alias_name":null,"gene_symbol":"BCL11B","hgnc_symbol":"BCL11B","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"14:99635624-99737861","ensembl_id":"ENSG00000127152"}},"GRch38":{"90":{"location":"14:99169287-99271524","ensembl_id":"ENSG00000127152"}}},"hgnc_date_symbol_changed":"2001-02-28"},"entity_type":"gene","entity_name":"BCL11B","confidence_level":"1","penetrance":null,"mode_of_pathogenicity":null,"publications":["29296816","27959755"],"evidence":["Expert Review Red","IUIS Classification February 2018"],"phenotypes":["?Immunodeficiency 49, 617237","Congenital abnormalities, neonatal teeth, dysmorphic facies, absent corpus callosum, neurocognitive deficits","Immunodeficiencies affecting cellular and humoral immunity","leaky SCID"],"mode_of_inheritance":"MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown","tags":[],"panel":{"id":398,"hash_id":null,"name":"Primary immunodeficiency","disease_group":"","disease_sub_group":"","status":"public","version":"1.132","version_created":"2019-09-27T14:37:49.085568Z","relevant_disorders":["Primary immunodeficiency disorders","A- or hypo-gammaglobulinaemia","Congenital neutropaenia","Agranulocytosis","Combined B and T cell defect","Inherited complement deficiency","SCID","Primary immune disorder","Primary immunodeficiency","A-gammaglobulinaemia","Agammaglobulinaemia","hypo-gammaglobulinaemia","hypogammaglobulinemia","immune deficiency syndromes","Severe combined immunodeficiency","Congenital neutopenia","Familial haemophagocytic lymphohistiocytic disorders","Familial hemophagocytic lymphohistiocytic disorders","PID","Sepsis","Disseminated non-tuberculous mycobacterial infection","R15"],"stats":{"number_of_genes":395,"number_of_strs":0,"number_of_regions":2},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."}]}},{"gene_data":{"alias":["CTIP-2","CTIP2","hRIT1-alpha"],"biotype":"protein_coding","hgnc_id":"HGNC:13222","gene_name":"B-cell CLL/lymphoma 11B","omim_gene":["606558"],"alias_name":null,"gene_symbol":"BCL11B","hgnc_symbol":"BCL11B","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"14:99635624-99737861","ensembl_id":"ENSG00000127152"}},"GRch38":{"90":{"location":"14:99169287-99271524","ensembl_id":"ENSG00000127152"}}},"hgnc_date_symbol_changed":"2001-02-28"},"entity_type":"gene","entity_name":"BCL11B","confidence_level":"3","penetrance":"unknown","mode_of_pathogenicity":null,"publications":["27959755","29985992"],"evidence":["Expert Review Green","Literature"],"phenotypes":["Intellectual disability","Intellectual developmental disorder with dysmorphic facies, speech delay, and T-cell abnormalities, 618092"],"mode_of_inheritance":"MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown","tags":[],"panel":{"id":285,"hash_id":"558aa423bb5a16630e15b63c","name":"Intellectual disability","disease_group":"Neurology and neurodevelopmental disorders","disease_sub_group":"Neurodevelopmental disorders","status":"public","version":"2.1065","version_created":"2019-10-07T13:42:16.019766Z","relevant_disorders":["Coarse facial features including Coffin-Siris-like disorders","ID","Moderate","severe or profound intellectual disability","Schizophrenia plus additional features","Intellectual disability - microarray","fragile X and sequencing"],"stats":{"number_of_genes":2253,"number_of_strs":11,"number_of_regions":57},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."},{"name":"Component Of Super Panel","slug":"component-of-super-panel","description":"This panel is a component of a Super Panel"}]}}]}