{"count":1,"next":null,"previous":null,"results":[{"gene_data":{"alias":["CARMEN","CIPER","mE10","c-E10","CLAP"],"biotype":"protein_coding","hgnc_id":"HGNC:989","gene_name":"B-cell CLL/lymphoma 10","omim_gene":["603517"],"alias_name":["CARD-like apoptotic protein","CARD-containing apoptotic signaling protein","CARD containing molecule enhancing NF-kB","caspase-recruiting domain-containing protein","CARD-containing proapoptotic protein"],"gene_symbol":"BCL10","hgnc_symbol":"BCL10","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"1:85731931-85742773","ensembl_id":"ENSG00000142867"}},"GRch38":{"90":{"location":"1:85266248-85277090","ensembl_id":"ENSG00000142867"}}},"hgnc_date_symbol_changed":"1999-01-08"},"entity_type":"gene","entity_name":"BCL10","confidence_level":"2","penetrance":null,"mode_of_pathogenicity":null,"publications":["25365219"],"evidence":["IUIS Classification February 2018","Victorian Clinical Genetics Services","Expert Review Amber","GRID V2.0"],"phenotypes":["Combined immunodeficiency with B cell, T cell, and fibroblast defects","?Immunodeficiency 37, 616098","Recurrent bacterial and viral infections, candidiasis, gastroenteritis","Immunodeficiencies affecting cellular and humoral immunity"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":398,"hash_id":null,"name":"Primary immunodeficiency","disease_group":"","disease_sub_group":"","status":"public","version":"1.132","version_created":"2019-09-27T14:37:49.085568Z","relevant_disorders":["Primary immunodeficiency disorders","A- or hypo-gammaglobulinaemia","Congenital neutropaenia","Agranulocytosis","Combined B and T cell defect","Inherited complement deficiency","SCID","Primary immune disorder","Primary immunodeficiency","A-gammaglobulinaemia","Agammaglobulinaemia","hypo-gammaglobulinaemia","hypogammaglobulinemia","immune deficiency syndromes","Severe combined immunodeficiency","Congenital neutopenia","Familial haemophagocytic lymphohistiocytic disorders","Familial hemophagocytic lymphohistiocytic disorders","PID","Sepsis","Disseminated non-tuberculous mycobacterial infection","R15"],"stats":{"number_of_genes":395,"number_of_strs":0,"number_of_regions":2},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."}]}}]}