{"count":2,"next":null,"previous":null,"results":[{"gene_data":{"alias":["RALDH2"],"biotype":"protein_coding","hgnc_id":"HGNC:15472","gene_name":"aldehyde dehydrogenase 1 family member A2","omim_gene":["603687"],"alias_name":["retinaldehyde dehydrogenase 2"],"gene_symbol":"ALDH1A2","hgnc_symbol":"ALDH1A2","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"15:58245622-58790065","ensembl_id":"ENSG00000128918"}},"GRch38":{"90":{"location":"15:57953424-58497866","ensembl_id":"ENSG00000128918"}}},"hgnc_date_symbol_changed":"2001-03-30"},"entity_type":"gene","entity_name":"ALDH1A2","confidence_level":"1","penetrance":"Complete","mode_of_pathogenicity":"","publications":["DOI: 10.1186/1471-2350-10-113"],"evidence":["Expert Review Red","Radboud University Medical Center, Nijmegen"],"phenotypes":["Tetralogy of Fallot (Pavan (2009) BMC Med Genet 10, 113)"],"mode_of_inheritance":"","tags":[],"panel":{"id":212,"hash_id":"583c128f8f62036f70db8d29","name":"Familial non syndromic congenital heart disease","disease_group":"Cardiovascular disorders","disease_sub_group":"Congenital heart disease","status":"public","version":"1.49","version_created":"2019-08-07T15:17:24.060112Z","relevant_disorders":["Fallots tetralogy","Hypoplastic Left Heart Syndrome","Left Ventricular Outflow Tract obstruction disorders","Pulmonary atresia","Transposition of the great vessels","Familial non-syndromic congenital heart disease","Familial congenital heart disease","Congenital heart disease","Syndromic congenital heart disease","Isomerism and laterality disorders"],"stats":{"number_of_genes":47,"number_of_strs":0,"number_of_regions":8},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"}]}},{"gene_data":{"alias":["RALDH2"],"biotype":"protein_coding","hgnc_id":"HGNC:15472","gene_name":"aldehyde dehydrogenase 1 family member A2","omim_gene":["603687"],"alias_name":["retinaldehyde dehydrogenase 2"],"gene_symbol":"ALDH1A2","hgnc_symbol":"ALDH1A2","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"15:58245622-58790065","ensembl_id":"ENSG00000128918"}},"GRch38":{"90":{"location":"15:57953424-58497866","ensembl_id":"ENSG00000128918"}}},"hgnc_date_symbol_changed":"2001-03-30"},"entity_type":"gene","entity_name":"ALDH1A2","confidence_level":"1","penetrance":"Complete","mode_of_pathogenicity":"","publications":[],"evidence":["Expert"],"phenotypes":[],"mode_of_inheritance":"","tags":[],"panel":{"id":126,"hash_id":"558ac48fbb5a16630dcfeaad","name":"Hearing loss","disease_group":"Hearing and ear disorders","disease_sub_group":"Non-syndromic hearing loss","status":"public","version":"2.2","version_created":"2019-09-03T14:01:56.987667Z","relevant_disorders":["Congenital hearing impairment","Autosomal dominant deafness","Congenital hearing impairment (profound/severe)","R67"],"stats":{"number_of_genes":358,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."},{"name":"GMS signed-off","slug":"gms-signed-off","description":"This panel has undergone review by a NHSE GMS disease specialist group and processes to be signed-off for use within the GMS."},{"name":"GMS Rare Disease","slug":"gms-rare-disease","description":"This panel type is used for GMS panels that are not virtual (i.e. could be a wet lab test)"}]}}]}