{"count":7,"next":null,"previous":null,"results":[{"gene_data":{"alias":[],"biotype":"protein_coding","hgnc_id":"HGNC:333","gene_name":"angiotensinogen","omim_gene":["106150"],"alias_name":["alpha-1 antiproteinase, antitrypsin"],"gene_symbol":"AGT","hgnc_symbol":"AGT","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"1:230838269-230850043","ensembl_id":"ENSG00000135744"}},"GRch38":{"90":{"location":"1:230702523-230714297","ensembl_id":"ENSG00000135744"}}},"hgnc_date_symbol_changed":"2001-06-29"},"entity_type":"gene","entity_name":"AGT","confidence_level":"1","penetrance":"Complete","mode_of_pathogenicity":"","publications":["24452034"],"evidence":["Expert Review Red","UKGTN","Radboud University Medical Center, Nijmegen"],"phenotypes":["{Hypertension, essential, susceptibility to}, 145500","{Preeclampsia, susceptibility to}Renal tubular dysgenesis, 267430"],"mode_of_inheritance":"Unknown","tags":[],"panel":{"id":314,"hash_id":"553f9697bb5a1616e5ed45d4","name":"Extreme early-onset hypertension","disease_group":"Renal and urinary tract disorders","disease_sub_group":"Disorders of function","status":"public","version":"1.10","version_created":"2018-12-16T17:33:34.572280Z","relevant_disorders":[],"stats":{"number_of_genes":25,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."}]}},{"gene_data":{"alias":[],"biotype":"protein_coding","hgnc_id":"HGNC:333","gene_name":"angiotensinogen","omim_gene":["106150"],"alias_name":["alpha-1 antiproteinase, antitrypsin"],"gene_symbol":"AGT","hgnc_symbol":"AGT","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"1:230838269-230850043","ensembl_id":"ENSG00000135744"}},"GRch38":{"90":{"location":"1:230702523-230714297","ensembl_id":"ENSG00000135744"}}},"hgnc_date_symbol_changed":"2001-06-29"},"entity_type":"gene","entity_name":"AGT","confidence_level":"1","penetrance":null,"mode_of_pathogenicity":"","publications":[],"evidence":["Expert Review Red","Expert list","Radboud University Medical Center, Nijmegen","Illumina TruGenome Clinical Sequencing Services"],"phenotypes":["Renal tubular dysgenesis (267430)"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":209,"hash_id":"58c8066b8f6203413360f1cf","name":"Ductal plate malformation","disease_group":"","disease_sub_group":"","status":"public","version":"1.10","version_created":"2019-06-20T15:10:58.988548Z","relevant_disorders":["Ductal plate malformation (DPM)","Polycystic liver disease"],"stats":{"number_of_genes":150,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"}]}},{"gene_data":{"alias":[],"biotype":"protein_coding","hgnc_id":"HGNC:333","gene_name":"angiotensinogen","omim_gene":["106150"],"alias_name":["alpha-1 antiproteinase, antitrypsin"],"gene_symbol":"AGT","hgnc_symbol":"AGT","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"1:230838269-230850043","ensembl_id":"ENSG00000135744"}},"GRch38":{"90":{"location":"1:230702523-230714297","ensembl_id":"ENSG00000135744"}}},"hgnc_date_symbol_changed":"2001-06-29"},"entity_type":"gene","entity_name":"AGT","confidence_level":"3","penetrance":"Complete","mode_of_pathogenicity":"","publications":[],"evidence":["Expert Review Green","UKGTN","Radboud University Medical Center, Nijmegen","Illumina TruGenome Clinical Sequencing Services"],"phenotypes":["Renal tubular dysgenesis, 267430"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":156,"hash_id":"5693974122c1fc251660fb1f","name":"Unexplained kidney failure in young people","disease_group":"Renal and urinary tract disorders","disease_sub_group":"Disorders of function","status":"public","version":"1.73","version_created":"2019-07-17T16:13:42.477129Z","relevant_disorders":["Familial IgA nephropathy and IgA vasculitis","End-stage renal disease - childhood onset"],"stats":{"number_of_genes":166,"number_of_strs":0,"number_of_regions":3},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"}]}},{"gene_data":{"alias":[],"biotype":"protein_coding","hgnc_id":"HGNC:333","gene_name":"angiotensinogen","omim_gene":["106150"],"alias_name":["alpha-1 antiproteinase, antitrypsin"],"gene_symbol":"AGT","hgnc_symbol":"AGT","hgnc_release":"2017-11-03T00:00:00","ensembl_genes":{"GRch37":{"82":{"location":"1:230838269-230850043","ensembl_id":"ENSG00000135744"}},"GRch38":{"90":{"location":"1:230702523-230714297","ensembl_id":"ENSG00000135744"}}},"hgnc_date_symbol_changed":"2001-06-29"},"entity_type":"gene","entity_name":"AGT","confidence_level":"3","penetrance":"Complete","mode_of_pathogenicity":"","publications":[],"evidence":["Expert Review Green","Radboud University Medical Center, Nijmegen","Illumina TruGenome Clinical Sequencing Services"],"phenotypes":["Renal Tubular Dysgenesis","{Hypertension, essential, susceptibility to}, 145500{Preeclampsia, susceptibility to}Renal tubular dysgenesis, 267430"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":234,"hash_id":"553f9696bb5a1616e5ed45d1","name":"CAKUT","disease_group":"Renal and urinary tract disorders","disease_sub_group":"Structural renal and urinary tract disease","status":"public","version":"1.39","version_created":"2019-06-20T15:14:56.833108Z","relevant_disorders":["Congenital Anomaly of the Kidneys and Urinary Tract (CAKUT)"],"stats":{"number_of_genes":65,"number_of_strs":0,"number_of_regions":1},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."}]}},{"gene_data":{"alias":[],"biotype":"protein_coding","hgnc_id":"HGNC:333","gene_name":"angiotensinogen","omim_gene":["106150"],"alias_name":["alpha-1 antiproteinase, antitrypsin"],"gene_symbol":"AGT","hgnc_symbol":"AGT","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"1:230838269-230850043","ensembl_id":"ENSG00000135744"}},"GRch38":{"90":{"location":"1:230702523-230714297","ensembl_id":"ENSG00000135744"}}},"hgnc_date_symbol_changed":"2001-06-29"},"entity_type":"gene","entity_name":"AGT","confidence_level":"3","penetrance":null,"mode_of_pathogenicity":"","publications":[],"evidence":["Expert Review Green"],"phenotypes":["Renal Tubular Dysgenesis","Renal tubular dysgenesis, 267430","{Hypertension, essential, susceptibility to}, 145500{Preeclampsia, susceptibility to}Renal tubular dysgenesis, 267430"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":493,"hash_id":null,"name":"Renal and urinary tract disorders","disease_group":"","disease_sub_group":"","status":"public","version":"1.18","version_created":"2019-07-04T13:55:26.963386Z","relevant_disorders":[],"stats":{"number_of_genes":177,"number_of_strs":0,"number_of_regions":3},"types":[{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."}]}},{"gene_data":{"alias":[],"biotype":"protein_coding","hgnc_id":"HGNC:333","gene_name":"angiotensinogen","omim_gene":["106150"],"alias_name":["alpha-1 antiproteinase, antitrypsin"],"gene_symbol":"AGT","hgnc_symbol":"AGT","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"1:230838269-230850043","ensembl_id":"ENSG00000135744"}},"GRch38":{"90":{"location":"1:230702523-230714297","ensembl_id":"ENSG00000135744"}}},"hgnc_date_symbol_changed":"2001-06-29"},"entity_type":"gene","entity_name":"AGT","confidence_level":"3","penetrance":null,"mode_of_pathogenicity":"","publications":[],"evidence":["Expert Review Green","Expert Review Green"],"phenotypes":["Renal Tubular Dysgenesis","{Hypertension, essential, susceptibility to}, 145500{Preeclampsia, susceptibility to}Renal tubular dysgenesis, 267430","Renal tubular dysgenesis, 267430"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":678,"hash_id":null,"name":"Unexplained paediatric onset end-stage renal disease","disease_group":"","disease_sub_group":"","status":"public","version":"0.43","version_created":"2019-09-25T12:25:36.245604Z","relevant_disorders":["R257"],"stats":{"number_of_genes":229,"number_of_strs":0,"number_of_regions":3},"types":[{"name":"GMS Rare Disease","slug":"gms-rare-disease","description":"This panel type is used for GMS panels that are not virtual (i.e. could be a wet lab test)"}]}},{"gene_data":{"alias":[],"biotype":"protein_coding","hgnc_id":"HGNC:333","gene_name":"angiotensinogen","omim_gene":["106150"],"alias_name":["alpha-1 antiproteinase, antitrypsin"],"gene_symbol":"AGT","hgnc_symbol":"AGT","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"1:230838269-230850043","ensembl_id":"ENSG00000135744"}},"GRch38":{"90":{"location":"1:230702523-230714297","ensembl_id":"ENSG00000135744"}}},"hgnc_date_symbol_changed":"2001-06-29"},"entity_type":"gene","entity_name":"AGT","confidence_level":"1","penetrance":null,"mode_of_pathogenicity":"","publications":[],"evidence":["Victorian Clinical Genetics Services"],"phenotypes":[],"mode_of_inheritance":"","tags":[],"panel":{"id":285,"hash_id":"558aa423bb5a16630e15b63c","name":"Intellectual disability","disease_group":"Neurology and neurodevelopmental disorders","disease_sub_group":"Neurodevelopmental disorders","status":"public","version":"2.1065","version_created":"2019-10-07T13:42:16.019766Z","relevant_disorders":["Coarse facial features including Coffin-Siris-like disorders","ID","Moderate","severe or profound intellectual disability","Schizophrenia plus additional features","Intellectual disability - microarray","fragile X and sequencing"],"stats":{"number_of_genes":2253,"number_of_strs":11,"number_of_regions":57},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."},{"name":"Component Of Super Panel","slug":"component-of-super-panel","description":"This panel is a component of a Super Panel"}]}}]}