{"count":1,"next":null,"previous":null,"results":[{"gene_data":{"alias":["KIAA0366","ADAMTS-4"],"biotype":"protein_coding","hgnc_id":"HGNC:219","gene_name":"ADAM metallopeptidase with thrombospondin type 1 motif 3","omim_gene":["605011"],"alias_name":null,"gene_symbol":"ADAMTS3","hgnc_symbol":"ADAMTS3","hgnc_release":"2017-11-03","ensembl_genes":{"GRch37":{"82":{"location":"4:73146686-73434516","ensembl_id":"ENSG00000156140"}},"GRch38":{"90":{"location":"4:72280969-72569386","ensembl_id":"ENSG00000156140"}}},"hgnc_date_symbol_changed":"1999-04-15"},"entity_type":"gene","entity_name":"ADAMTS3","confidence_level":"3","penetrance":null,"mode_of_pathogenicity":null,"publications":["28985353","28687807","26446156","30450763"],"evidence":["Expert Review Green","Expert list","London South GLH","UKGTN","Other"],"phenotypes":["Hennekam syndrome","Hennekam lymphangiectasia-lymphedema syndrome 3"],"mode_of_inheritance":"BIALLELIC, autosomal or pseudoautosomal","tags":[],"panel":{"id":65,"hash_id":"57ee82ef8f62035c9b2d0487","name":"Primary lymphoedema","disease_group":"Cardiovascular disorders","disease_sub_group":"Lymphatic Disorders","status":"public","version":"2.0","version_created":"2019-10-02T14:10:33.689992Z","relevant_disorders":["Lymphatic Disorders","Meiges disease","Meige disease","Milroy disease","Lymphoedema distichiasis","Lipoedema disease","R136"],"stats":{"number_of_genes":51,"number_of_strs":0,"number_of_regions":0},"types":[{"name":"Rare Disease 100K","slug":"rare-disease-100k","description":"Rare Disease 100K"},{"name":"GMS Rare Disease Virtual","slug":"gms-rare-disease-virtual","description":"This is a panel for the Genomic Medicine Service for an exome/genome/panel based test that requires a virtual gene panel for rare disease in the Test Directory."},{"name":"GMS signed-off","slug":"gms-signed-off","description":"This panel has undergone review by a NHSE GMS disease specialist group and processes to be signed-off for use within the GMS."}]}}]}