A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1387878773 18p11.32 18 49554 T C R G 2 2 missense 0.962 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,gnomAD rs545258011 18p11.32 18 49553 C T R K 2 2 2.0E-4 missense 0.78 possibly damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1470447021 18p11.32 18 49552 C A R S 2 2 missense 0.948 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs112198597 18p11.32 18 49551 C T E K 3 3 missense 0.815 possibly damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs112198597 18p11.32 18 49551 C G E Q 3 3 missense 0.989 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs12955069 18p11.32 18 49548 T A I F 4 4 0.3305 missense 0.977 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs12955069 18p11.32 18 49548 T G I L 4 4 0.3305 missense 0.381 benign 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs62075716 18p11.32 18 49546 G C I M 4 4 0.3327 missense 0.983 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1438834752 18p11.32 18 49547 A C I S 4 4 missense 0.985 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs12955069 18p11.32 18 49548 T C I V 4 4 0.3305 missense 0.748 possibly damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC rs778800164 18p11.32 18 49544 A C V G 5 5 missense 0.972 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC rs768982037 18p11.32 18 49541 A C L R 6 6 missense 0.509 possibly damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs201650431 18p11.32 18 49538 G A T M 7 7 missense 0.13 benign 0.05 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs201650431 18p11.32 18 49538 G C T R 7 7 missense 0.045 benign 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs112517337 18p11.32 18 49533 T C T A 9 9 missense 0.005 benign 1.0 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs755882042 18p11.32 18 49532 G A T I 9 9 missense 0.012 benign 0.27 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs113491878 18p11.32 18 49530 C G G R 10 10 missense 0.997 probably damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs113491878 18p11.32 18 49530 C T G R 10 10 missense 0.997 probably damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1490889962 18p11.32 18 49529 C A G V 10 10 missense 1.0 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1019150281 18p11.32 18 49527 G A Q * 11 11 stop gained 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,TOPMed,gnomAD rs113088646 18p11.32 18 49523 C T C Y 12 12 missense 0.334 benign 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1329025788 18p11.32 18 49520 C T G E 13 13 missense 0.994 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1438106680 18p11.32 18 49521 C T G R 13 13 missense 0.891 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1400756920 18p11.32 18 49518 T C N D 14 14 missense 0.835 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs188417265 18p11.32 18 49516 G C N K 14 14 0.007987 missense 0.984 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs184028554 18p11.32 18 49515 G A Q * 15 15 0.002995 stop gained 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1419037309 18p11.32 18 49513 C A Q H 15 15 missense 0.061 benign 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs184028554 18p11.32 18 49515 G T Q K 15 15 0.002995 missense 0.039 benign 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1395409182 18p11.32 18 49512 T A I F 16 16 missense 0.923 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1476942419 18p11.32 18 49509 C T G S 17 17 missense 0.598 possibly damaging 0.04 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs576451750 18p11.32 18 49506 C T A T 18 18 3.99E-4 missense 0.017 benign 0.26 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1330923961 18p11.32 18 49232 C T W * 21 21 stop gained 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1397912884 18p11.32 18 49233 C T W * 21 21 stop gained 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs988046523 18p11.32 18 49229 C A E D 22 22 missense 0.077 benign 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs764802328 18p11.32 18 49231 C T E K 22 22 missense 0.869 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs764802328 18p11.32 18 49231 C G E Q 22 22 missense 0.394 benign 0.08 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1351629505 18p11.32 18 49227 A G V A 23 23 missense 0.833 possibly damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1423366847 18p11.32 18 49225 T C I V 24 24 missense 0.078 benign 0.08 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1181120796 18p11.32 18 49221 G A S F 25 25 missense 0.993 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1438220109 18p11.32 18 49218 T C D G 26 26 missense 0.146 benign 0.14 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1237962303 18p11.32 18 49214 T A E D 27 27 missense 0.195 benign 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1488615231 18p11.32 18 49212 T C H R 28 28 missense 0.897 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs759205009 18p11.32 18 49213 G A H Y 28 28 missense 0.992 probably damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1266652540 18p11.32 18 49209 G C A G 29 29 missense 0.003 benign 1.0 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1266652540 18p11.32 18 49209 G A A V 29 29 missense 0.368 benign 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1257827186 18p11.32 18 49207 T C I V 30 30 missense 0.055 benign 0.1 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1286628403 18p11.32 18 49204 C T D N 31 31 missense 0.017 benign 0.09 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1286628403 18p11.32 18 49204 C A D Y 31 31 missense 0.756 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1374293069 18p11.32 18 49198 C A A S 33 33 missense 0.007 benign 0.38 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1374293069 18p11.32 18 49198 C T A T 33 33 missense 0.005 benign 1.0 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1308272041 18p11.32 18 49197 G A A V 33 33 missense 0.01 benign 0.08 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1441868219 18p11.32 18 49195 C T G S 34 34 missense 0.992 probably damaging 0.04 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1369966919 18p11.32 18 49191 G A T I 35 35 missense 0.017 benign 0.12 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1369966919 18p11.32 18 49191 G T T N 35 35 missense 0.017 benign 0.38 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs953463061 18p11.32 18 49189 A C Y D 36 36 missense 0.955 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs562086001 18p11.32 18 49185 T A H L 37 37 2.0E-4 missense 0.003 benign 0.3 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs562086001 18p11.32 18 49185 T G H P 37 37 2.0E-4 missense 0.386 benign 0.1 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs775578263 18p11.32 18 49184 G T H Q 37 37 missense 0.007 benign 0.29 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs769158011 18p11.32 18 49186 G A H Y 37 37 missense 0.011 benign 0.48 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs770019787 18p11.32 18 49182 C T G E 38 38 missense 0.999 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1418424938 18p11.32 18 49183 C T G R 38 38 missense 0.999 probably damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1435318368 18p11.32 18 49180 C T D N 39 39 missense 0.058 benign 0.08 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs770688705 18p11.32 18 49177 T A S C 40 40 missense 0.879 possibly damaging 0.06 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,gnomAD rs543395284 18p11.32 18 49176 C T S N 40 40 5.99E-4 missense 0.01 benign 0.17 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs770688705 18p11.32 18 49177 T G S R 40 40 missense 0.772 possibly damaging 0.05 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,gnomAD rs543395284 18p11.32 18 49176 C G S T 40 40 5.99E-4 missense 0.014 benign 0.04 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs747625203 18p11.32 18 49173 T G H P 41 41 missense 0.0 benign 0.08 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1029503466 18p11.32 18 49174 G A H Y 41 41 missense 0.092 benign 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs753512261 18p11.32 18 49167 T G Q P 43 43 missense 0.992 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC rs757585184 18p11.32 18 49164 A C L R 44 44 missense 0.083 benign 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1299460806 18p11.32 18 49165 G C L V 44 44 missense 0.139 benign 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs764516966 18p11.32 18 49158 C T R H 46 46 missense 0.272 benign 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs764516966 18p11.32 18 49158 C G R P 46 46 missense 0.99 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs765299362 18p11.32 18 49156 T A I F 47 47 missense 0.367 benign 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs765299362 18p11.32 18 49156 T G I L 47 47 missense 0.192 benign 0.09 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs759799529 18p11.32 18 49155 A G I T 47 47 missense 0.864 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs765299362 18p11.32 18 49156 T C I V 47 47 missense 0.049 benign 0.06 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1344936967 18p11.32 18 49152 T C N S 48 48 missense 0.022 benign 0.36 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed rs4413042 18p11.32 18 49147 G A H Y 50 50 0.3389 missense 0.0 benign 1.0 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1487401011 18p11.32 18 49143 T G H P 51 51 missense 0.035 benign 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,TOPMed,gnomAD rs539886505 18p11.32 18 49144 G A H Y 51 51 9.98E-4 missense 0.0 benign 1.0 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed rs746783264 18p11.32 18 49141 G C H D 52 52 missense 0.0 benign 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed rs746783264 18p11.32 18 49141 G T H N 52 52 missense 0.0 benign 1.0 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs773002009 18p11.32 18 49140 T C H R 52 52 missense 0.001 benign 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed rs746783264 18p11.32 18 49141 G A H Y 52 52 missense 0.011 benign 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1376943190 18p11.32 18 49138 C T E K 53 53 missense 0.747 possibly damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC rs771958743 18p11.32 18 49132 T C S G 55 55 missense 0.01 benign 0.09 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed rs778607416 18p11.32 18 49130 G T S R 55 55 missense 0.265 benign 0.07 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs572454839 18p11.32 18 49129 C T G S 56 56 3.99E-4 missense 0.044 benign 0.23 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs766475635 18p11.32 18 49040 G C Y * 59 59 stop gained 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs760846380 18p11.32 18 49039 C T V M 60 60 missense 0.761 possibly damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs750637928 18p11.32 18 49036 G C P A 61 61 missense 0.476 possibly damaging 0.04 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1398579300 18p11.32 18 49035 G A P L 61 61 missense 0.999 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs750637928 18p11.32 18 49036 G A P S 61 61 missense 0.986 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1395083782 18p11.32 18 49033 G A R C 62 62 missense 0.964 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs761734293 18p11.32 18 49032 C T R H 62 62 missense 0.922 probably damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1395083782 18p11.32 18 49033 G T R S 62 62 missense 0.999 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs762972763 18p11.32 18 49030 C A A S 63 63 missense 0.319 benign 0.09 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs762972763 18p11.32 18 49030 C T A T 63 63 missense 0.231 benign 0.04 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs775211157 18p11.32 18 49029 G A A V 63 63 missense 0.884 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs769319442 18p11.32 18 49026 A G V A 64 64 missense 0.185 benign 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs769319442 18p11.32 18 49026 A T V E 64 64 missense 0.937 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1383342108 18p11.32 18 49024 G A L F 65 65 missense 0.973 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs780924282 18p11.32 18 49021 C T V M 66 66 missense 0.644 possibly damaging 0.13 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs779233846 18p11.32 18 49015 G T L M 68 68 missense 0.998 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs779233846 18p11.32 18 49015 G C L V 68 68 missense 0.971 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs755544151 18p11.32 18 49008 G A P L 70 70 missense 0.938 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs780046475 18p11.32 18 49005 C A G V 71 71 missense 0.983 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1379510495 18p11.32 18 49002 G A T I 72 72 missense 0.997 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs750430958 18p11.32 18 48999 A G M T 73 73 missense 0.938 probably damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs756240782 18p11.32 18 49000 T C M V 73 73 missense 0.444 benign 0.03 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs767785913 18p11.32 18 48996 T C D G 74 74 missense 0.978 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1388028875 18p11.32 18 48993 G C S C 75 75 missense 0.967 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1420246099 18p11.32 18 48991 C T V M 76 76 missense 0.983 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs375240601 18p11.32 18 48987 T C H R 77 77 missense 0.0 benign 1.0 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1317037190 18p11.32 18 48988 G A H Y 77 77 missense 0.387 benign 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs532998254 18p11.32 18 48984 G T S * 78 78 2.0E-4 stop gained 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs532998254 18p11.32 18 48984 G A S L 78 78 2.0E-4 missense 0.142 benign 0.06 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs770625255 18p11.32 18 48981 C T G E 79 79 missense 0.964 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1266778873 18p11.32 18 48978 G A P L 80 80 missense 0.046 benign 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC rs746658044 18p11.32 18 48979 G A P S 80 80 missense 0.031 benign 0.05 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs963464883 18p11.32 18 48973 C G G R 82 82 missense 0.988 probably damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs963464883 18p11.32 18 48973 C T G R 82 82 missense 0.988 probably damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1014844064 18p11.32 18 48970 G T Q K 83 83 missense 0.007 benign 0.23 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1284559371 18p11.32 18 48961 T C R G 86 86 missense 0.965 probably damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs749606114 18p11.32 18 48959 C A R S 86 86 missense 0.95 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1413297856 18p11.32 18 48946 T C I V 91 91 missense 0.012 benign 1.0 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs529481653 18p11.32 18 48942 G A S F 92 92 3.99E-4 missense 0.0 benign 1.0 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1345836393 18p11.32 18 48943 A G S P 92 92 missense 0.035 benign 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs537178211 18p11.32 18 48940 C G G R 93 93 missense 0.998 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs537178211 18p11.32 18 48940 C T G S 93 93 missense 0.917 probably damaging 0.04 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1239188490 18p11.32 18 48447 C A G V 93 93 missense 0.997 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs747094450 18p11.32 18 48443 C A Q H 94 94 missense 0.158 benign 0.03 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1295206731 18p11.32 18 48442 A G C R 95 95 missense 0.005 benign 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1249303660 18p11.32 18 48439 C A G W 96 96 missense 1.0 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1291935452 18p11.32 18 48432 C G G A 98 98 missense 0.641 possibly damaging 0.03 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs772402414 18p11.32 18 48433 C T G R 98 98 missense 0.98 probably damaging 0.03 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC rs748285550 18p11.32 18 48427 T G N H 100 100 missense 0.998 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1309736831 18p11.32 18 48421 C A A S 102 102 missense 0.991 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1309736831 18p11.32 18 48421 C T A T 102 102 missense 0.978 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs753627604 18p11.32 18 48418 T C K E 103 103 missense 0.89 possibly damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1297868619 18p11.32 18 48416 C A K N 103 103 missense 0.984 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1437262891 18p11.32 18 48414 C G G A 104 104 missense 0.985 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs539398416 18p11.32 18 48412 G A R C 105 105 2.0E-4 missense 0.832 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs539398416 18p11.32 18 48412 G C R G 105 105 2.0E-4 missense 0.088 benign 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs767011946 18p11.32 18 48411 C T R H 105 105 missense 0.001 benign 1.0 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs767011946 18p11.32 18 48411 C A R L 105 105 missense 0.125 benign 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs539398416 18p11.32 18 48412 G T R S 105 105 2.0E-4 missense 0.088 benign 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1467549988 18p11.32 18 48409 A C Y D 106 106 missense 1.0 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs761569983 18p11.32 18 48405 G A T I 107 107 missense 0.984 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1381267016 18p11.32 18 48406 T G T P 107 107 missense 0.498 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1247968015 18p11.32 18 48403 C A E * 108 108 stop gained 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs201395302 18p11.32 18 48399 C T G D 109 109 0.2903 missense 0.999 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs763757988 18p11.32 18 48400 C T G S 109 109 missense 0.999 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs201395302 18p11.32 18 48399 C A G V 109 109 0.2903 missense 0.998 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs771620230 18p11.32 18 48397 C T A T 110 110 missense 0.251 benign 0.05 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs149504840 18p11.32 18 48396 G A A V 110 110 0.009385 missense 0.215 benign 0.06 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs779035280 18p11.32 18 48391 G T L M 112 112 missense 0.998 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1332019062 18p11.32 18 48388 T C T A 113 113 missense 0.003 benign 0.07 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs4798106 18p11.32 18 48387 G T T K 113 113 missense 0.009 benign 0.03 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs4798106 18p11.32 18 48387 G A T M 113 113 missense 0.0 benign 0.17 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs4798106 18p11.32 18 48387 G C T R 113 113 missense 0.013 benign 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs780807381 18p11.32 18 48382 A T S T 115 115 missense 0.025 benign 0.06 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs763663474 18p11.32 18 48378 A G V A 116 116 missense 0.555 possibly damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs763663474 18p11.32 18 48378 A T V E 116 116 missense 0.974 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1418252051 18p11.32 18 48374 C T M I 117 117 missense 0.007 benign 0.05 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,gnomAD rs538094535 18p11.32 18 48375 A T M K 117 117 2.0E-4 missense 0.51 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs12104022 18p11.32 18 48371 G T D E 118 118 missense 0.127 benign 0.09 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1333207856 18p11.32 18 48372 T C D G 118 118 missense 0.989 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1433430932 18p11.32 18 48369 A G V A 119 119 missense 0.97 probably damaging 0.03 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs766816556 18p11.32 18 48370 C T V I 119 119 missense 0.266 benign 0.06 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs773876447 18p11.32 18 48364 T C R G 121 121 missense 0.974 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1204415659 18p11.32 18 48354 G A A V 124 124 missense 0.317 benign 0.05 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1484731717 18p11.32 18 48352 C T E K 125 125 missense 0.62 possibly damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1259950244 18p11.32 18 48346 A C C G 127 127 missense 0.992 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs761803418 18p11.32 18 48339 C A C F 129 129 missense 0.961 probably damaging 0.03 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs761803418 18p11.32 18 48339 C T C Y 129 129 missense 0.593 possibly damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs768819050 18p11.32 18 48330 C T G D 132 132 missense 1.0 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs768819050 18p11.32 18 48330 C A G V 132 132 missense 1.0 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs749508015 18p11.32 18 48325 G A Q * 134 134 stop gained 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1467934294 18p11.32 18 48323 C G Q H 134 134 missense 0.983 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs775306076 18p11.32 18 48324 T C Q R 134 134 missense 0.466 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1479820381 18p11.32 18 48315 T C H R 137 137 missense 0.989 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs199686837 18p11.32 18 48316 G A H Y 137 137 0.001597 missense 0.472 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1259203799 18p11.32 18 48312 G A S F 138 138 missense 0.996 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs781025853 18p11.32 18 48313 A G S P 138 138 missense 0.982 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs781025853 18p11.32 18 48313 A T S T 138 138 missense 0.795 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1259203799 18p11.32 18 48312 G T S Y 138 138 missense 0.997 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1261003818 18p11.32 18 48303 C T G E 141 141 missense 0.99 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs777329159 18p11.32 18 48304 C T G R 141 141 missense 0.844 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs777329159 18p11.32 18 48304 C G G R 141 141 missense 0.844 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs777329159 18p11.32 18 48304 C A G W 141 141 missense 0.844 possibly damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs756577325 18p11.32 18 48297 G A T I 143 143 missense 0.999 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1318632486 18p11.32 18 48289 C T G R 146 146 missense 0.999 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1318632486 18p11.32 18 48289 C A G W 146 146 missense 1.0 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs750749130 18p11.32 18 48283 C T G S 148 148 missense 0.998 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs767923637 18p11.32 18 48282 C A G V 148 148 missense 0.928 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs762368798 18p11.32 18 48279 G A T I 149 149 missense 0.346 benign 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs762368798 18p11.32 18 48279 G T T N 149 149 missense 0.907 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs774363232 18p11.32 18 48277 G A L F 150 150 missense 0.78 possibly damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1160065063 18p11.32 18 48271 T G I L 152 152 missense 0.079 benign 0.25 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs763213400 18p11.32 18 48270 A G I T 152 152 missense 0.795 possibly damaging 0.03 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs769966908 18p11.32 18 48266 A C S R 153 153 missense 0.985 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs745671287 18p11.32 18 48264 T C K R 154 154 missense 0.454 possibly damaging 0.06 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,gnomAD rs560480888 18p11.32 18 48262 T C I V 155 155 2.0E-4 missense 0.06 benign 0.11 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs777195142 18p11.32 18 48258 C A R L 156 156 missense 0.109 benign 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs777195142 18p11.32 18 48258 C G R P 156 156 missense 0.961 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs777195142 18p11.32 18 48258 C T R Q 156 156 missense 0.269 benign 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs770836498 18p11.32 18 48259 G A R W 156 156 missense 0.334 benign 0.04 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1194125581 18p11.32 18 48253 C A E * 158 158 stop gained 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1378190295 18p11.32 18 48250 A G Y H 159 159 missense 0.998 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1247629890 18p11.32 18 48246 G A P L 160 160 missense 0.996 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs747619668 18p11.32 18 48247 G A P S 160 160 missense 0.802 possibly damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1419954670 18p11.32 18 48243 T C D G 161 161 missense 0.95 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs754618971 18p11.32 18 48241 T C R G 162 162 missense 0.991 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1299711770 18p11.32 18 48240 C T R K 162 162 missense 0.941 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs750811826 18p11.32 18 48238 T C I V 163 163 missense 0.12 benign 0.05 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs764539607 18p11.32 18 48233 T C I M 164 164 missense 0.039 benign 1.0 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs752087069 18p11.32 18 48234 A G I T 164 164 missense 0.027 benign 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs757746515 18p11.32 18 48235 T C I V 164 164 missense 0.205 benign 0.05 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1318235524 18p11.32 18 48231 T C N S 165 165 missense 0.041 benign 0.31 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs200634579 18p11.32 18 48228 G A T I 166 166 missense 0.991 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs200634579 18p11.32 18 48228 G T T K 166 166 missense 0.956 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs4798104 18p11.32 18 48224 G C F L 167 167 missense 0.9 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs770734683 18p11.32 18 48220 T C I V 169 169 missense 0.005 benign 1.0 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs773230880 18p11.32 18 48216 A G L P 170 170 missense 0.855 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs760336295 18p11.32 18 48217 G C L V 170 170 missense 0.012 benign 1.0 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs4798103 18p11.32 18 48213 G A P L 171 171 missense 0.998 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs772067658 18p11.32 18 48214 G A P S 171 171 missense 0.913 probably damaging 0.04 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs4798102 18p11.32 18 48210 G T S * 172 172 stop gained 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs4798102 18p11.32 18 48210 G A S L 172 172 missense 1.0 probably damaging 0.06 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1334614520 18p11.32 18 48207 G A P L 173 173 missense 0.997 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs548607698 18p11.32 18 48208 G A P S 173 173 2.0E-4 missense 0.99 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1453289190 18p11.32 18 48205 T C K E 174 174 missense 0.847 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs530218509 18p11.32 18 48203 C G K N 174 174 2.0E-4 missense 0.961 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs778260314 18p11.32 18 48204 T C K R 174 174 missense 0.144 benign 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs765266407 18p11.32 18 48201 A G V A 175 175 missense 1.0 probably damaging 0.03 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs562881439 18p11.32 18 48202 C A V L 175 175 2.0E-4 missense 0.999 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs562881439 18p11.32 18 48202 C T V M 175 175 2.0E-4 missense 1.0 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs543588177 18p11.32 18 48198 G A S L 176 176 2.0E-4 missense 0.979 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs543588177 18p11.32 18 48198 G C S W 176 176 2.0E-4 missense 0.999 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1201063266 18p11.32 18 48189 A T V E 179 179 missense 1.0 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs200370756 18p11.32 18 48190 C T V M 179 179 missense 0.952 probably damaging 0.05 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs768260123 18p11.32 18 48181 G C P A 182 182 missense 1.0 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs775242556 18p11.32 18 48177 T C Y C 183 183 missense 1.0 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs747418100 18p11.32 18 48173 G C N K 184 184 missense 1.0 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs769266739 18p11.32 18 48174 T C N S 184 184 missense 0.999 probably damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs62075712 18p11.32 18 48171 G A A V 185 185 missense 0.953 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs758975464 18p11.32 18 48168 G C T S 186 186 missense 0.407 benign 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs755092451 18p11.32 18 48166 G A L F 187 187 missense 0.996 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs755092451 18p11.32 18 48166 G C L V 187 187 missense 0.599 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs756267995 18p11.32 18 48159 A G V A 189 189 missense 0.924 probably damaging 0.04 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1187871987 18p11.32 18 48160 C G V L 189 189 missense 0.084 benign 0.07 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs761898165 18p11.32 18 48156 T G H P 190 190 missense 0.994 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs761898165 18p11.32 18 48156 T C H R 190 190 missense 0.943 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs767415344 18p11.32 18 48157 G A H Y 190 190 missense 0.488 possibly damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1243667883 18p11.32 18 48154 G A Q * 191 191 stop gained 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1178937583 18p11.32 18 48151 G T L I 192 192 missense 0.961 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1428703257 18p11.32 18 48146 T C I M 193 193 missense 0.255 benign 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs774442392 18p11.32 18 48148 T C I V 193 193 missense 0.007 benign 1.0 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs545743571 18p11.32 18 48140 G T N K 195 195 2.0E-4 missense 0.992 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs769531648 18p11.32 18 48139 C A A S 196 196 missense 0.021 benign 0.48 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs769531648 18p11.32 18 48139 C T A T 196 196 missense 0.005 benign 1.0 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs546512302 18p11.32 18 48138 G A A V 196 196 missense 0.386 benign 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs779429437 18p11.32 18 48134 A C D E 197 197 missense 1.0 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs748448260 18p11.32 18 48135 T C D G 197 197 missense 1.0 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs772442130 18p11.32 18 48136 C G D H 197 197 missense 1.0 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs755392064 18p11.32 18 48131 C A E D 198 198 missense 0.031 benign 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1357133181 18p11.32 18 48132 T C E G 198 198 missense 0.163 benign 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1261990095 18p11.32 18 48133 C T E K 198 198 missense 0.119 benign 0.04 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs779966993 18p11.32 18 48129 G A T I 199 199 missense 0.972 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs779966993 18p11.32 18 48129 G T T N 199 199 missense 0.942 probably damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs756424855 18p11.32 18 48126 A C F C 200 200 missense 0.983 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs756424855 18p11.32 18 48126 A G F S 200 200 missense 0.875 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs757120589 18p11.32 18 48123 C A C F 201 201 missense 0.961 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1340850272 18p11.32 18 48124 A C C G 201 201 missense 0.995 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1340850272 18p11.32 18 48124 A G C R 201 201 missense 0.998 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs757120589 18p11.32 18 48123 C T C Y 201 201 missense 0.593 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs56279059 18p11.32 18 48121 T A I L 202 202 missense 0.592 possibly damaging 0.08 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs762773846 18p11.32 18 48120 A C I R 202 202 missense 1.0 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs762773846 18p11.32 18 48120 A G I T 202 202 missense 1.0 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs56279059 18p11.32 18 48121 T C I V 202 202 missense 0.875 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs775101672 18p11.32 18 48117 T G D A 203 203 missense 0.992 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs775101672 18p11.32 18 48117 T C D G 203 203 missense 0.993 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1411772422 18p11.32 18 48118 C T D N 203 203 missense 0.759 possibly damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1411772422 18p11.32 18 48118 C A D Y 203 203 missense 0.999 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed rs764643676 18p11.32 18 48114 T C N S 204 204 missense 0.962 probably damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs572018726 18p11.32 18 48112 C T E K 205 205 0.001597 missense 0.606 possibly damaging 0.03 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs553305085 18p11.32 18 48108 G T A E 206 206 7.99E-4 missense 0.997 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs553305085 18p11.32 18 48108 G C A G 206 206 7.99E-4 missense 0.979 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs770533409 18p11.32 18 48109 C G A P 206 206 missense 0.996 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs553305085 18p11.32 18 48108 G A A V 206 206 7.99E-4 missense 0.602 possibly damaging 0.03 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs781593576 18p11.32 18 48101 A T Y * 208 208 stop gained 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs745874938 18p11.32 18 48102 T C Y C 208 208 missense 0.998 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs745874938 18p11.32 18 48102 T A Y F 208 208 missense 0.576 possibly damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs780237444 18p11.32 18 48103 A G Y H 208 208 missense 0.752 possibly damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1316940314 18p11.32 18 48097 T A I L 210 210 missense 1.0 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs751446302 18p11.32 18 48096 A G I T 210 210 missense 1.0 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1316940314 18p11.32 18 48097 T C I V 210 210 missense 0.999 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs535123276 18p11.32 18 48094 A T C S 211 211 2.0E-4 missense 0.613 possibly damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1332361963 18p11.32 18 48092 A C C W 211 211 missense 0.997 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1229750314 18p11.32 18 48093 C T C Y 211 211 missense 0.996 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1444452688 18p11.32 18 48090 G A S F 212 212 missense 0.003 benign 1.0 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1444452688 18p11.32 18 48090 G T S Y 212 212 missense 0.017 benign 0.09 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,gnomAD rs574183142 18p11.32 18 48087 C T R K 213 213 2.0E-4 missense 0.217 benign 0.04 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs752593689 18p11.32 18 48086 C G R S 213 213 missense 0.95 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs765158968 18p11.32 18 48085 T C T A 214 214 missense 0.998 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs556017101 18p11.32 18 48084 G A T I 214 214 2.0E-4 missense 1.0 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1177430464 18p11.32 18 48081 A G L P 215 215 missense 0.999 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs538410980 18p11.32 18 48075 A C L R 217 217 2.0E-4 missense 0.993 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs774846121 18p11.32 18 48072 G A P L 218 218 missense 0.122 benign 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1230703082 18p11.32 18 48073 G A P S 218 218 missense 0.007 benign 0.36 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs775864904 18p11.32 18 48070 T C T A 219 219 missense 0.393 benign 0.08 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1243476480 18p11.32 18 48066 G T P H 220 220 missense 0.999 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs770383497 18p11.32 18 48067 G A P S 220 220 missense 0.992 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs770383497 18p11.32 18 48067 G T P T 220 220 missense 0.877 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1310170638 18p11.32 18 48063 G A T I 221 221 missense 0.975 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC rs781397004 18p11.32 18 48060 T A Y F 222 222 missense 0.983 probably damaging 0.05 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1345180014 18p11.32 18 48051 A G L P 225 225 missense 0.828 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1305021066 18p11.32 18 48052 G C L V 225 225 missense 0.323 benign 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs777997730 18p11.32 18 48047 G T N K 226 226 missense 0.986 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1371209764 18p11.32 18 48048 T C N S 226 226 missense 0.86 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs758136900 18p11.32 18 48045 T C H R 227 227 missense 0.684 possibly damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1347854285 18p11.32 18 48043 G C L V 228 228 missense 0.731 possibly damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs754889639 18p11.32 18 48037 A C S A 230 230 missense 0.766 possibly damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs753388190 18p11.32 18 48036 G A S F 230 230 missense 0.994 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1159319556 18p11.32 18 48033 G C A G 231 231 missense 0.005 benign 0.04 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1405395204 18p11.32 18 48030 G A T I 232 232 missense 0.712 possibly damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs760379558 18p11.32 18 48028 T C M V 233 233 missense 0.03 benign 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1480513607 18p11.32 18 48024 C T S N 234 234 missense 0.801 possibly damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1270950032 18p11.32 18 48023 A T S R 234 234 missense 0.996 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs750057440 18p11.32 18 48021 C T G E 235 235 missense 1.0 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1218162427 18p11.32 18 48018 A G V A 236 236 missense 0.891 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs767129791 18p11.32 18 48019 C T V I 236 236 missense 0.058 benign 0.28 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1315318800 18p11.32 18 48016 T C T A 237 237 missense 0.821 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs775872785 18p11.32 18 48012 G A T I 238 238 missense 0.994 probably damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs775872785 18p11.32 18 48012 G T T K 238 238 missense 0.988 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1341479444 18p11.32 18 48008 G T C * 239 239 stop gained 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1404906830 18p11.32 18 48010 A G C R 239 239 missense 0.894 possibly damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs760084652 18p11.32 18 48009 C T C Y 239 239 missense 0.856 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs776913605 18p11.32 18 48007 G T L M 240 240 missense 0.979 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs534449800 18p11.32 18 48004 G A R C 241 241 0.003994 missense 0.998 probably damaging 0.05 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs773341142 18p11.32 18 48003 C T R H 241 241 missense 0.649 possibly damaging 0.04 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs772290413 18p11.32 18 48001 A T F I 242 242 missense 0.986 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs779908287 18p11.32 18 47992 G A Q * 245 245 stop gained 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1188022401 18p11.32 18 47989 G T L M 246 246 missense 1.0 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1484803855 18p11.32 18 47984 A C N K 247 247 missense 0.526 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs755625724 18p11.32 18 47980 C G D H 249 249 missense 0.999 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs755625724 18p11.32 18 47980 C A D Y 249 249 missense 1.0 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs199980273 18p11.32 18 47973 C T R Q 251 251 0.001797 missense 0.45 possibly damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs4798099 18p11.32 18 47974 G A R W 251 251 missense 0.998 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs765688512 18p11.32 18 47969 C A K N 252 252 missense 0.434 benign 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1475452245 18p11.32 18 47970 T G K T 252 252 missense 0.936 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1287863889 18p11.32 18 47968 G T L M 253 253 missense 0.971 probably damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1452940171 18p11.32 18 47967 A C L R 253 253 missense 0.993 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs760174521 18p11.32 18 47965 C T A T 254 254 missense 0.146 benign 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC rs777285692 18p11.32 18 47964 G A A V 254 254 missense 0.726 possibly damaging 0.03 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs760693769 18p11.32 18 47962 C T V M 255 255 missense 0.348 benign 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs772224338 18p11.32 18 47959 T C N D 256 256 missense 0.983 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1184400610 18p11.32 18 47954 C A M I 257 257 missense 0.302 benign 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1184400610 18p11.32 18 47954 C T M I 257 257 missense 0.302 benign 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1260806852 18p11.32 18 47955 A G M T 257 257 missense 0.968 probably damaging 0.03 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1426459240 18p11.32 18 47956 T C M V 257 257 missense 0.035 benign 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs201509207 18p11.32 18 47952 A G V A 258 258 missense 0.186 benign 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs774190063 18p11.32 18 47949 G A P L 259 259 missense 1.0 probably damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1203102698 18p11.32 18 47950 G A P S 259 259 missense 1.0 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1225891954 18p11.32 18 47945 A C F L 260 260 missense 0.908 possibly damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs779997991 18p11.32 18 47944 G C P A 261 261 missense 1.0 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs756027734 18p11.32 18 47943 G C P R 261 261 missense 1.0 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs779997991 18p11.32 18 47944 G A P S 261 261 missense 1.0 probably damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs779997991 18p11.32 18 47944 G T P T 261 261 missense 1.0 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs780719733 18p11.32 18 47940 C A R L 262 262 missense 0.791 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs780719733 18p11.32 18 47940 C T R Q 262 262 missense 0.269 benign 0.03 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs530151405 18p11.32 18 47941 G A R W 262 262 3.99E-4 missense 0.334 benign 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs756923308 18p11.32 18 47937 A T L Q 263 263 missense 1.0 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1200068678 18p11.32 18 47925 A T M K 267 267 missense 0.7 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs751208150 18p11.32 18 47926 T C M V 267 267 missense 0.021 benign 0.1 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs763777245 18p11.32 18 47922 G A P L 268 268 missense 0.978 probably damaging 0.08 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs754209791 18p11.32 18 47920 C T G S 269 269 missense 0.851 possibly damaging 0.05 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1407768834 18p11.32 18 47914 C A A S 271 271 missense 0.973 probably damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs767622177 18p11.32 18 47910 G A P L 272 272 missense 0.998 probably damaging 0.03 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs562979399 18p11.32 18 47911 G A P S 272 272 2.0E-4 missense 0.994 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs562979399 18p11.32 18 47911 G T P T 272 272 2.0E-4 missense 0.996 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1480573207 18p11.32 18 47904 G A T I 274 274 missense 0.776 possibly damaging 0.06 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs761742233 18p11.32 18 47905 T A T S 274 274 missense 0.049 benign 0.05 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs762758295 18p11.32 18 47901 C T S N 275 275 missense 0.679 possibly damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs55979329 18p11.32 18 47898 C T R Q 276 276 0.1693 missense 0.257 benign 0.11 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,TOPMed,gnomAD rs550771025 18p11.32 18 47899 G A R W 276 276 2.0E-4 missense 0.986 probably damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs769657294 18p11.32 18 47895 C G G A 277 277 missense 0.633 possibly damaging 0.04 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1335792870 18p11.32 18 47896 C A G C 277 277 missense 0.302 benign 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1335792870 18p11.32 18 47896 C G G R 277 277 missense 0.413 benign 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs780620955 18p11.32 18 47890 G A Q * 279 279 stop gained 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1486141297 18p11.32 18 47888 C A Q H 279 279 missense 0.097 benign 0.05 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1212697212 18p11.32 18 47887 G C Q E 280 280 missense 0.019 benign 0.04 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1255113297 18p11.32 18 47886 T A Q L 280 280 missense 0.279 benign 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs746481152 18p11.32 18 47882 G C Y * 281 281 stop gained 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs770485135 18p11.32 18 47883 T C Y C 281 281 missense 0.998 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs777594487 18p11.32 18 47881 G C R G 282 282 missense 0.061 benign 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs758103852 18p11.32 18 47880 C T R Q 282 282 missense 0.116 benign 0.08 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs777594487 18p11.32 18 47881 G A R W 282 282 missense 0.151 benign 0.03 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs754297821 18p11.32 18 47878 C T A T 283 283 missense 0.266 benign 0.06 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1166839204 18p11.32 18 47873 C A L F 284 284 missense 0.904 possibly damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1179725806 18p11.32 18 47869 C A V L 286 286 missense 0.46 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs564085116 18p11.32 18 47863 C T E K 288 288 2.0E-4 missense 0.411 benign 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1489947676 18p11.32 18 47860 G C L V 289 289 missense 0.689 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1319492563 18p11.32 18 47857 T C T A 290 290 missense 0.506 possibly damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1328715994 18p11.32 18 47856 G A T I 290 290 missense 0.346 benign 0.03 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1319492563 18p11.32 18 47857 T A T S 290 290 missense 0.59 possibly damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1350913632 18p11.32 18 47854 G A Q * 291 291 stop gained 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1262182994 18p11.32 18 47850 T C Q R 292 292 missense 0.93 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs751590346 18p11.32 18 47846 C T M I 293 293 missense 0.034 benign 0.03 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs751590346 18p11.32 18 47846 C A M I 293 293 missense 0.034 benign 0.03 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs572006507 18p11.32 18 47847 A C M R 293 293 2.0E-4 missense 0.828 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs572006507 18p11.32 18 47847 A G M T 293 293 2.0E-4 missense 0.106 benign 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs200791031 18p11.32 18 47845 A G F L 294 294 2.0E-4 missense 0.975 probably damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs775328407 18p11.32 18 47840 A T D E 295 295 missense 0.896 possibly damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs541406627 18p11.32 18 47841 T C D G 295 295 0.005591 missense 0.985 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1322617631 18p11.32 18 47838 G C A G 296 296 missense 0.091 benign 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1346805772 18p11.32 18 47835 T G K T 297 297 missense 0.878 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1157117659 18p11.32 18 47831 G T N K 298 298 missense 1.0 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC rs759191393 18p11.32 18 47828 C T M I 299 299 missense 0.949 probably damaging 0.06 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1430100227 18p11.32 18 47825 C A M I 300 300 missense 0.177 benign 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs770728290 18p11.32 18 47827 T A M L 300 300 missense 0.079 benign 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC rs746569083 18p11.32 18 47826 A G M T 300 300 missense 0.99 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs770728290 18p11.32 18 47827 T C M V 300 300 missense 0.529 possibly damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs574120814 18p11.32 18 47824 C A A S 301 301 5.99E-4 missense 0.845 possibly damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs771918718 18p11.32 18 47823 G A A V 301 301 missense 0.141 benign 0.08 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs747790884 18p11.32 18 47821 C G A P 302 302 missense 0.972 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs778372899 18p11.32 18 47820 G A A V 302 302 missense 0.839 possibly damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs199800204 18p11.32 18 47818 A G C R 303 303 0.002196 missense 0.998 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs543933409 18p11.32 18 47817 C G C S 303 303 7.99E-4 missense 0.818 possibly damaging 0.26 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs543933409 18p11.32 18 47817 C T C Y 303 303 7.99E-4 missense 0.867 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs757737404 18p11.32 18 47809 G A R C 306 306 missense 0.169 benign 0.03 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs751676593 18p11.32 18 47808 C T R H 306 306 missense 0.083 benign 0.05 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs757737404 18p11.32 18 47809 G T R S 306 306 missense 0.794 possibly damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs764151478 18p11.32 18 47806 G A H Y 307 307 missense 0.187 benign 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs752972576 18p11.32 18 47803 C T G S 308 308 missense 0.996 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs12326077 18p11.32 18 47800 A G C R 309 309 missense 0.0 benign 1.0 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs776272416 18p11.32 18 47799 C T C Y 309 309 missense 0.003 benign 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs766383345 18p11.32 18 47797 A G Y H 310 310 missense 1.0 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs760689319 18p11.32 18 47793 A C L R 311 311 missense 0.994 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs771722703 18p11.32 18 47790 G T T K 312 312 missense 0.895 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs771722703 18p11.32 18 47790 G A T M 312 312 missense 0.904 possibly damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC rs772917100 18p11.32 18 47791 T G T P 312 312 missense 0.993 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs10853307 18p11.32 18 47787 A G V A 313 313 missense 0.161 benign 0.35 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1371720241 18p11.32 18 47788 C T V M 313 313 missense 0.529 possibly damaging 0.04 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC rs781378322 18p11.32 18 47779 T C I V 316 316 missense 0.03 benign 0.44 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs558884673 18p11.32 18 47767 G A R C 320 320 0.0 missense 0.868 possibly damaging 0.05 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs11874906 18p11.32 18 47766 C T R H 320 320 0.002596 missense 0.028 benign 0.1 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs11874906 18p11.32 18 47766 C A R L 320 320 0.002596 missense 0.007 benign 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs558884673 18p11.32 18 47767 G T R S 320 320 0.0 missense 0.026 benign 0.03 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs758473790 18p11.32 18 47762 C T M I 321 321 missense 0.034 benign 0.14 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs758473790 18p11.32 18 47762 C G M I 321 321 missense 0.034 benign 0.14 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1205003848 18p11.32 18 47764 T C M V 321 321 missense 0.056 benign 0.28 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs752673544 18p11.32 18 47760 G T P H 322 322 missense 0.844 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1162763762 18p11.32 18 47761 G A P S 322 322 missense 0.005 benign 1.0 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1162763762 18p11.32 18 47761 G T P T 322 322 missense 0.029 benign 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs567155504 18p11.32 18 47756 C T M I 323 323 2.0E-4 missense 0.574 possibly damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1463040136 18p11.32 18 47757 A G M T 323 323 missense 0.207 benign 0.38 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs753736696 18p11.32 18 47748 A C V G 326 326 missense 0.434 benign 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1227571342 18p11.32 18 47743 C T E K 328 328 missense 0.769 possibly damaging 0.04 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs773287538 18p11.32 18 47735 C T M I 330 330 missense 0.229 benign 0.11 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs773287538 18p11.32 18 47735 C A M I 330 330 missense 0.229 benign 0.11 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs773287538 18p11.32 18 47735 C G M I 330 330 missense 0.229 benign 0.11 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,gnomAD rs536968900 18p11.32 18 47737 T G M L 330 330 2.0E-4 missense 0.15 benign 0.08 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1225094701 18p11.32 18 47731 T C N D 332 332 missense 0.449 possibly damaging 0.03 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs761430207 18p11.32 18 47728 T C I V 333 333 missense 0.011 benign 1.0 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs773711353 18p11.32 18 47725 G A Q * 334 334 stop gained 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1181943594 18p11.32 18 47720 A T D E 335 335 missense 0.125 benign 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs768393245 18p11.32 18 47721 T C D G 335 335 missense 0.125 benign 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1412165277 18p11.32 18 47722 C T D N 335 335 missense 0.001 benign 1.0 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs748886565 18p11.32 18 47718 T C K R 336 336 missense 0.514 possibly damaging 0.15 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs748886565 18p11.32 18 47718 T G K T 336 336 missense 0.992 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs777108347 18p11.32 18 47716 T C N D 337 337 missense 0.921 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs777108347 18p11.32 18 47716 T A N Y 337 337 missense 0.608 possibly damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1300055910 18p11.32 18 47709 C T S N 339 339 missense 0.014 benign 0.06 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1408952351 18p11.32 18 47700 G A A V 342 342 missense 0.003 benign 1.0 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1313288530 18p11.32 18 47697 T A D V 343 343 missense 0.857 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs10853305 18p11.32 18 47692 A G F L 345 345 2.0E-4 missense 0.001 benign 0.15 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs758883590 18p11.32 18 47689 G T P T 346 346 missense 1.0 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,TOPMed rs550960768 18p11.32 18 47684 G C D E 347 347 2.0E-4 missense 0.088 benign 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,TOPMed rs550960768 18p11.32 18 47684 G T D E 347 347 2.0E-4 missense 0.088 benign 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs10853304 18p11.32 18 47686 C T D N 347 347 missense 0.001 benign 1.0 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1044769834 18p11.32 18 47683 T C N D 348 348 missense 1.0 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1044769834 18p11.32 18 47683 T G N H 348 348 missense 1.0 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs780356885 18p11.32 18 47681 G C N K 348 348 missense 1.0 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC rs755288868 18p11.32 18 47682 T G N T 348 348 missense 1.0 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs191210390 18p11.32 18 47680 C T V I 349 349 3.99E-4 missense 0.184 benign 0.21 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs191210390 18p11.32 18 47680 C A V L 349 349 3.99E-4 missense 0.541 possibly damaging 0.03 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1353260889 18p11.32 18 47671 C T A T 352 352 missense 0.638 possibly damaging 0.04 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs571756449 18p11.32 18 47670 G A A V 352 352 2.0E-4 missense 0.94 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs751147149 18p11.32 18 47668 C T V I 353 353 missense 0.18 benign 0.15 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs762462848 18p11.32 18 47665 A C C G 354 354 missense 0.995 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs775123796 18p11.32 18 47661 T A D V 355 355 missense 0.966 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs989390207 18p11.32 18 47655 G C P R 357 357 missense 0.995 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,gnomAD rs527517095 18p11.32 18 47653 G C P A 358 358 2.0E-4 missense 0.976 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1174548125 18p11.32 18 47652 G A P L 358 358 missense 0.998 probably damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs923731334 18p11.32 18 47649 C A R L 359 359 missense 0.028 benign 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs923731334 18p11.32 18 47649 C T R Q 359 359 missense 0.116 benign 0.08 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs200636062 18p11.32 18 47650 G A R W 359 359 3.99E-4 missense 0.964 probably damaging 0.05 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs541691709 18p11.32 18 47646 C T G E 360 360 2.0E-4 missense 0.995 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs773538325 18p11.32 18 47647 C T G R 360 360 missense 0.998 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs748593984 18p11.32 18 47641 T C K E 362 362 missense 0.089 benign 0.04 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs779418332 18p11.32 18 47636 C T M I 363 363 missense 0.882 possibly damaging 0.06 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1321330949 18p11.32 18 47637 A C M R 363 363 missense 0.476 possibly damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs780446921 18p11.32 18 47631 G C A G 365 365 missense 0.112 benign 0.14 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs77835015 18p11.32 18 47632 C T A T 365 365 0.005791 missense 0.829 possibly damaging 0.03 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs780446921 18p11.32 18 47631 G A A V 365 365 missense 0.123 benign 0.24 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs756381274 18p11.32 18 47629 T C T A 366 366 missense 0.732 possibly damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs781129660 18p11.32 18 47628 G A T I 366 366 missense 0.585 possibly damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs781129660 18p11.32 18 47628 G T T N 366 366 missense 0.99 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs781129660 18p11.32 18 47628 G C T S 366 366 missense 0.844 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs757276513 18p11.32 18 47623 T A I F 368 368 missense 0.954 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs757276513 18p11.32 18 47623 T G I L 368 368 missense 0.229 benign 0.07 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs764020920 18p11.32 18 47622 A T I N 368 368 missense 0.998 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs764020920 18p11.32 18 47622 A G I T 368 368 missense 0.929 probably damaging 0.04 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1283483500 18p11.32 18 47616 T C N S 370 370 missense 0.9 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1345612416 18p11.32 18 47613 T C N S 371 371 missense 0.031 benign 1.0 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs10775434 18p11.32 18 47611 C T A T 372 372 missense 0.001 benign 1.0 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs60908131 18p11.32 18 47610 G A A V 372 372 0.02436 missense 0.125 benign 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1271029897 18p11.32 18 47608 C T A T 373 373 missense 0.971 probably damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs773628469 18p11.32 18 47607 G A A V 373 373 missense 0.965 probably damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs772340644 18p11.32 18 47605 T C I V 374 374 missense 0.078 benign 0.06 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs762172166 18p11.32 18 47593 A G F L 378 378 missense 1.0 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC rs774752471 18p11.32 18 47592 A T F Y 378 378 missense 1.0 probably damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1441011826 18p11.32 18 47589 G A T I 379 379 missense 0.01 benign 0.03 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC rs769159732 18p11.32 18 47586 C T C Y 380 380 missense 0.191 benign 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1015916219 18p11.32 18 47583 A G V A 381 381 missense 0.65 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs770205901 18p11.32 18 47581 A C S A 382 382 missense 0.123 benign 0.12 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs781505741 18p11.32 18 47562 A T M K 388 388 missense 0.879 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs781505741 18p11.32 18 47562 A C M R 388 388 missense 0.916 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs781505741 18p11.32 18 47562 A G M T 388 388 missense 0.858 possibly damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1266851498 18p11.32 18 47563 T C M V 388 388 missense 0.055 benign 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs757003232 18p11.32 18 47560 A T F I 389 389 missense 0.631 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs746774101 18p11.32 18 47556 C T R K 390 390 missense 0.019 benign 0.15 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs576855326 18p11.32 18 47555 C A R S 390 390 2.0E-4 missense 0.667 possibly damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs58330678 18p11.32 18 47554 G A R C 391 391 0.03415 missense 0.174 benign 0.03 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs754431142 18p11.32 18 47553 C T R H 391 391 missense 0.935 probably damaging 0.03 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs754431142 18p11.32 18 47553 C A R L 391 391 missense 0.642 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs754431142 18p11.32 18 47553 C G R P 391 391 missense 0.174 benign 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs58330678 18p11.32 18 47554 G T R S 391 391 0.03415 missense 0.801 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs753494513 18p11.32 18 47551 T C K E 392 392 missense 0.999 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs766015109 18p11.32 18 47548 C T A T 393 393 missense 0.956 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs540810211 18p11.32 18 47547 G A A V 393 393 0.006589 missense 0.767 possibly damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs573450046 18p11.32 18 47542 G A L F 395 395 3.99E-4 missense 0.215 benign 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs573450046 18p11.32 18 47542 G C L V 395 395 3.99E-4 missense 0.058 benign 0.07 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs948852958 18p11.32 18 47537 G C H Q 396 396 missense 0.91 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1462712534 18p11.32 18 47539 G A H Y 396 396 missense 0.279 benign 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1176276012 18p11.32 18 47534 C T W * 397 397 stop gained 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1254712327 18p11.32 18 47532 T C Y C 398 398 missense 0.995 probably damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs775769723 18p11.32 18 47530 T C T A 399 399 missense 0.071 benign 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs555218463 18p11.32 18 47529 G A T M 399 399 7.99E-4 missense 0.988 probably damaging 0.03 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs775769723 18p11.32 18 47530 T G T P 399 399 missense 0.95 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs555218463 18p11.32 18 47529 G C T R 399 399 7.99E-4 missense 0.961 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1226705485 18p11.32 18 47526 C T G D 400 400 missense 0.2 benign 0.03 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs536904088 18p11.32 18 47524 C T E K 401 401 0.001198 missense 0.945 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs748101171 18p11.32 18 47516 C T M I 403 403 missense 0.622 possibly damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs758328960 18p11.32 18 47518 T G M L 403 403 missense 0.436 benign 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1465512883 18p11.32 18 47517 A C M R 403 403 missense 0.888 possibly damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1465512883 18p11.32 18 47517 A G M T 403 403 missense 0.253 benign 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs758328960 18p11.32 18 47518 T C M V 403 403 missense 0.436 benign 0.04 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1411090405 18p11.32 18 47507 C T M I 406 406 missense 0.015 benign 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs754515404 18p11.32 18 47509 T G M L 406 406 missense 0.007 benign 0.08 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs753296043 18p11.32 18 47505 T G E A 407 407 missense 0.962 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1446466576 18p11.32 18 47500 T C T A 409 409 missense 0.175 benign 0.04 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs765999531 18p11.32 18 47499 G C T S 409 409 missense 0.018 benign 0.09 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs751933713 18p11.32 18 47497 C T E K 410 410 missense 0.194 benign 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1341907490 18p11.32 18 47489 C G E D 412 412 missense 0.838 possibly damaging 0.06 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1412025706 18p11.32 18 47491 C T E K 412 412 missense 0.573 possibly damaging 0.03 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,gnomAD rs557071884 18p11.32 18 47487 C T S N 413 413 2.0E-4 missense 0.023 benign 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs765796696 18p11.32 18 47486 G T S R 413 413 missense 0.877 possibly damaging 0.03 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs776748095 18p11.32 18 47484 T A N I 414 414 missense 0.997 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs759707677 18p11.32 18 47485 T A N Y 414 414 missense 0.998 probably damaging 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1373960376 18p11.32 18 47482 T A M L 415 415 missense 0.01 benign 0.16 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1373960376 18p11.32 18 47482 T C M V 415 415 missense 0.01 benign 0.11 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs771095974 18p11.32 18 47479 T C N D 416 416 missense 0.449 possibly damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs539061012 18p11.32 18 47477 G C N K 416 416 2.0E-4 missense 0.151 benign 0.05 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs747244629 18p11.32 18 47478 T C N S 416 416 missense 0.027 benign 0.03 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs778844661 18p11.32 18 47474 G C D E 417 417 missense 0.736 possibly damaging 0.01 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs747898283 18p11.32 18 47475 T C D G 417 417 missense 0.268 benign 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs113336758 18p11.32 18 47476 C T D N 417 417 missense 0.908 possibly damaging 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs768560432 18p11.32 18 47470 C G V L 419 419 missense 0.058 benign 0.07 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1482907300 18p11.32 18 47467 A C S A 420 420 missense 0.027 benign 0.14 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1482907300 18p11.32 18 47467 A T S T 420 420 missense 0.023 benign 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs755778269 18p11.32 18 47460 T C Y C 422 422 missense 0.0 unknown 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1243348670 18p11.32 18 47457 T A Q L 423 423 missense 0.0 unknown 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1243348670 18p11.32 18 47457 T C Q R 423 423 missense 0.0 unknown 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs750103557 18p11.32 18 47455 G A Q * 424 424 stop gained 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs750103557 18p11.32 18 47455 G C Q E 424 424 missense 0.0 unknown 0.03 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs780641694 18p11.32 18 47450 A C Y * 425 425 stop gained 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1290085483 18p11.32 18 47451 T A Y F 425 425 missense 0.0 unknown 0.08 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs758861544 18p11.32 18 47449 G A Q * 426 426 stop gained 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs753059118 18p11.32 18 47445 T C D G 427 427 missense 0.0 unknown 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1421080397 18p11.32 18 47446 C T D N 427 427 missense 0.0 unknown 0.07 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs546717223 18p11.32 18 47439 G A T M 429 429 2.0E-4 missense 0.0 unknown 0.03 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs367958683 18p11.32 18 47437 C T A T 430 430 0.004992 missense 0.0 unknown 0.06 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs766497807 18p11.32 18 47436 G A A V 430 430 missense 0.0 unknown 0.37 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed,gnomAD rs1378758905 18p11.32 18 47432 C A E D 431 431 missense 0.0 unknown 1.0 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs11081070 18p11.32 18 47434 C T E K 431 431 0.008187 missense 0.0 unknown 0.17 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1364229912 18p11.32 18 47431 C T E K 432 432 missense 0.0 unknown 0.02 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1348242192 18p11.32 18 47425 C T E K 434 434 missense 0.0 unknown 0.22 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1276354422 18p11.32 18 47424 T A E V 434 434 missense 0.0 unknown 0.18 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1243334743 18p11.32 18 47420 A C D E 435 435 missense 0.0 unknown 0.31 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1208893863 18p11.32 18 47422 C G D H 435 435 missense 0.0 unknown 0.06 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1208893863 18p11.32 18 47422 C T D N 435 435 missense 0.0 unknown 0.19 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs1441742077 18p11.32 18 47421 T A D V 435 435 missense 0.0 unknown 0.1 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs774102370 18p11.32 18 47411 A T Y * 438 438 stop gained 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,gnomAD rs761646858 18p11.32 18 47412 T C Y C 438 438 missense 0.0 unknown 0.14 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs768648538 18p11.32 18 47409 G T A D 439 439 missense 0.0 unknown 0.68 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B TOPMed rs923125569 18p11.32 18 47410 C T A T 439 439 missense 0.0 unknown 0.6 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B ExAC,TOPMed,gnomAD rs779797128 18p11.32 18 47407 C T E K 440 440 missense 0.0 unknown 0.05 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs562842438 18p11.32 18 47400 T C E G 442 442 9.98E-4 missense 0.0 unknown 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1318597724 18p11.32 18 47401 C T E K 442 442 missense 0.0 unknown 0.05 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,ExAC,TOPMed,gnomAD rs562842438 18p11.32 18 47400 T A E V 442 442 9.98E-4 missense 0.0 unknown 0.0 deleterious - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B 1000Genomes,TOPMed rs543847261 18p11.32 18 47397 A G V A 443 443 9.98E-4 missense 0.0 unknown 0.52 tolerated - low confidence 0 A6NNZ2 TUBB8B Tubulin beta 8B gnomAD rs1489182805 18p11.32 18 47394 G A A V 444 444 missense 0.0 unknown 0.08 tolerated - low confidence 0