ID   M0R2A0_HUMAN            Unreviewed;       371 AA.
AC   M0R2A0;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   16-JAN-2019, entry version 33.
DE   SubName: Full=ER membrane protein complex subunit 10 {ECO:0000313|Ensembl:ENSP00000472420};
GN   Name=EMC10 {ECO:0000313|Ensembl:ENSP00000472420};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000472420, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000472420, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000472420}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2013) to UniProtKB.
RN   [3] {ECO:0000213|PubMed:25944712}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=25944712;
RA   Vaca Jacome A.S., Rabilloud T., Schaeffer-Reiss C., Rompais M.,
RA   Ayoub D., Lane L., Bairoch A., Van Dorsselaer A., Carapito C.;
RT   "N-terminome analysis of the human mitochondrial proteome.";
RL   Proteomics 15:2519-2524(2015).
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DR   EMBL; AC020909; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; M0R2A0; -.
DR   EPD; M0R2A0; -.
DR   jPOST; M0R2A0; -.
DR   MaxQB; M0R2A0; -.
DR   PRIDE; M0R2A0; -.
DR   Ensembl; ENST00000598585; ENSP00000472420; ENSG00000161671.
DR   UCSC; uc061brc.1; human.
DR   EuPathDB; HostDB:ENSG00000161671.16; -.
DR   HGNC; HGNC:27609; EMC10.
DR   OpenTargets; ENSG00000161671; -.
DR   eggNOG; KOG4827; Eukaryota.
DR   eggNOG; ENOG4111PEN; LUCA.
DR   GeneTree; ENSGT00390000004520; -.
DR   ChiTaRS; EMC10; human.
DR   Proteomes; UP000005640; Chromosome 19.
DR   Bgee; ENSG00000161671; Expressed in 199 organ(s), highest expression level in pituitary gland.
DR   ExpressionAtlas; M0R2A0; baseline and differential.
DR   InterPro; IPR029615; Emc10.
DR   PANTHER; PTHR21397:SF4; PTHR21397:SF4; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|EPD:M0R2A0,
KW   ECO:0000213|MaxQB:M0R2A0, ECO:0000213|PeptideAtlas:M0R2A0};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     27       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        28    371       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5004003751.
SQ   SEQUENCE   371 AA;  38975 MW;  7CE3F93060243D36 CRC64;
     MAAASAGATR LLLLLLMAVA APSRARGSGC RAGTGARGAG AEGREGEACG TVGLLLEHSF
     EIDDSANFRK RGSLLWNQQD GTLSLSQRQL SEEERGRLRD VAALNGLYRV RIPRRPGALD
     GLEAGGYVSS FVPACSLVES HLSDQLTLHV DVAGNVVGVS VVTHPGGCRG HEVEDVDLEL
     FNTSVQLQPP TTAPGPETAA FIERLEMEQA QKAKNPQEQK SFFAKYWMYI IPVVLFLMMS
     GAPDTGGQGG GGGGGGGGGS GRPLSSAFCW QRSSWTGAFG TAAGVSCARL PHGPMQPQGL
     PPCPWSRARD PGHYASSDLA SPYPEPMQSG NMPPSLQPLC LCSRWSHPPV PGWARWSCPG
     SCSAPLTLTL D
//