ID   M0R1W3_HUMAN            Unreviewed;       509 AA.
AC   M0R1W3;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   16-JAN-2019, entry version 38.
DE   SubName: Full=Zinc finger protein 85 {ECO:0000313|Ensembl:ENSP00000472145};
DE   Flags: Fragment;
GN   Name=ZNF85 {ECO:0000313|Ensembl:ENSP00000472145};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000472145, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000472145, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000472145}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2013) to UniProtKB.
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DR   EMBL; AC008739; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; M0R1W3; -.
DR   EPD; M0R1W3; -.
DR   jPOST; M0R1W3; -.
DR   PeptideAtlas; M0R1W3; -.
DR   PRIDE; M0R1W3; -.
DR   Ensembl; ENST00000596534; ENSP00000472145; ENSG00000105750.
DR   UCSC; uc060wfl.1; human.
DR   EuPathDB; HostDB:ENSG00000105750.14; -.
DR   HGNC; HGNC:13160; ZNF85.
DR   OpenTargets; ENSG00000105750; -.
DR   eggNOG; KOG1721; Eukaryota.
DR   eggNOG; COG5048; LUCA.
DR   GeneTree; ENSGT00940000154251; -.
DR   Proteomes; UP000005640; Chromosome 19.
DR   Bgee; ENSG00000105750; Expressed in 194 organ(s), highest expression level in sperm.
DR   ExpressionAtlas; M0R1W3; baseline and differential.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   Pfam; PF00096; zf-C2H2; 13.
DR   SMART; SM00355; ZnF_C2H2; 14.
DR   SUPFAM; SSF57667; SSF57667; 8.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 14.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 14.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:M0R1W3};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT   SIGNAL        1     20       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        21    509       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5004005343.
FT   DOMAIN      122    145       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      150    177       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      178    205       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      206    233       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      234    261       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      262    289       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      290    317       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      318    345       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      346    373       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      374    401       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      402    429       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      430    457       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      458    485       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      486    509       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   NON_TER     509    509       {ECO:0000313|Ensembl:ENSP00000472145}.
SQ   SEQUENCE   509 AA;  58821 MW;  55BECBD93FB3EADE CRC64;
     MSYELLRKVY ILMLLRSVLY ASVRIMCSHF AQDLWPEQNI KDSFQKVTLK RYGKCRHENL
     PLRKGCESMD ECKMHKGGCN GLNQCLTATQ SKIFQCDKYV KVAHKFSNSN RHEIRHTKKK
     PFKCTKCGKS FGMISCLTEH SRIHTRVNFY KCEECGKAFN WSSTLTKHKR IHTGEKPYKC
     EECGKAFNQS SNLIKHKKIH TGEKPYKCEE CGKTFNRFST LTTHKIIHTG EKPYKCKECG
     KAFNRSSTLT THRKIHTGEK PYKCEECGKA FKQSSNLTTH KIIHTGEKPY KCKKCGKAFN
     QSAHLTTHEV IHTGEKPYKC EKCGKAFNHF SHLTTHKIIH TGEKPYKCKE CGKAFKHSST
     LTKHKIIHTG EKPYKCKECE KAFNQSSKLT EHKKIHTGEK PYECEKCGKA FNQSSNLTRH
     KKSHTEEKPY KCEECGKGFK WPSTLTIHKI IHTGEKPYKC EECGKAFNQS SKLTKHKKIH
     TGEKPYTCEE CGKAFNQSSN LTKHKRIHT
//