ID   M0R1I2_HUMAN            Unreviewed;       286 AA.
AC   M0R1I2;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   16-JAN-2019, entry version 38.
DE   SubName: Full=Urokinase plasminogen activator surface receptor {ECO:0000313|Ensembl:ENSP00000471881};
GN   Name=PLAUR {ECO:0000313|Ensembl:ENSP00000471881};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000471881, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000471881, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000471881}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2013) to UniProtKB.
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DR   EMBL; AC005525; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC006953; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_001287966.1; NM_001301037.1.
DR   UniGene; Hs.466871; -.
DR   ProteinModelPortal; M0R1I2; -.
DR   jPOST; M0R1I2; -.
DR   MaxQB; M0R1I2; -.
DR   PeptideAtlas; M0R1I2; -.
DR   PRIDE; M0R1I2; -.
DR   Ensembl; ENST00000601723; ENSP00000471881; ENSG00000011422.
DR   GeneID; 5329; -.
DR   UCSC; uc060zmt.1; human.
DR   CTD; 5329; -.
DR   EuPathDB; HostDB:ENSG00000011422.11; -.
DR   HGNC; HGNC:9053; PLAUR.
DR   OpenTargets; ENSG00000011422; -.
DR   GeneTree; ENSGT00940000153599; -.
DR   OrthoDB; 1102918at2759; -.
DR   ChiTaRS; PLAUR; human.
DR   GenomeRNAi; 5329; -.
DR   Proteomes; UP000005640; Chromosome 19.
DR   Bgee; ENSG00000011422; Expressed in 221 organ(s), highest expression level in bone marrow.
DR   ExpressionAtlas; M0R1I2; baseline and differential.
DR   GO; GO:0030377; F:urokinase plasminogen activator receptor activity; IEA:InterPro.
DR   GO; GO:0030162; P:regulation of proteolysis; IEA:InterPro.
DR   InterPro; IPR018363; CD59_antigen_CS.
DR   InterPro; IPR016054; LY6_UPA_recep-like.
DR   InterPro; IPR033084; U-PAR.
DR   PANTHER; PTHR10624:SF6; PTHR10624:SF6; 2.
DR   Pfam; PF00021; UPAR_LY6; 2.
DR   SMART; SM00134; LU; 2.
DR   PROSITE; PS00983; LY6_UPAR; 2.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|EPD:M0R1I2,
KW   ECO:0000213|MaxQB:M0R1I2, ECO:0000213|PeptideAtlas:M0R1I2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     22       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        23    286       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5004004107.
FT   DOMAIN       23    110       UPAR/Ly6. {ECO:0000259|SMART:SM00134}.
FT   DOMAIN      115    207       UPAR/Ly6. {ECO:0000259|SMART:SM00134}.
SQ   SEQUENCE   286 AA;  31638 MW;  76AB999111869226 CRC64;
     MGHPPLLPLL LLLHTCVPAS WGLRCMQCKT NGDCRVEECA LGQDLCRTTI VRLWEEGEEL
     ELVEKSCTHS EKTNRTLSYR TGLKITSLTE VVCGLDLCNQ GNSGRAVTYS RSRYLECISC
     GSSDMSCERG RHQSLQCRSP EEQCLDVVTH WIQEGEEGRP KDDRHLRGCG YLPGCPGSNG
     FHNNDTFHFL KCCNTTKCNE GPKPKNQSYM VRGCATASMC QHAHLGDAFS MNHIDVSCCT
     KSGCNHPDLD VQYRSGAAPQ PGPAHLSLTI TLLMTARLWG GTLLWT
//