ID   M0R1G1_HUMAN            Unreviewed;       331 AA.
AC   M0R1G1;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   16-JAN-2019, entry version 29.
DE   SubName: Full=Protein GPR108 {ECO:0000313|Ensembl:ENSP00000471846};
DE   Flags: Fragment;
GN   Name=GPR108 {ECO:0000313|Ensembl:ENSP00000471846};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000471846, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000471846, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000471846}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2013) to UniProtKB.
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DR   EMBL; AC008760; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; M0R1G1; -.
DR   EPD; M0R1G1; -.
DR   jPOST; M0R1G1; -.
DR   MaxQB; M0R1G1; -.
DR   PeptideAtlas; M0R1G1; -.
DR   PRIDE; M0R1G1; -.
DR   Ensembl; ENST00000597706; ENSP00000471846; ENSG00000125734.
DR   UCSC; uc060skz.1; human.
DR   EuPathDB; HostDB:ENSG00000125734.13; -.
DR   HGNC; HGNC:17829; GPR108.
DR   eggNOG; KOG2569; Eukaryota.
DR   eggNOG; ENOG410XQAQ; LUCA.
DR   GeneTree; ENSGT00940000160446; -.
DR   ChiTaRS; GPR108; human.
DR   Proteomes; UP000005640; Chromosome 19.
DR   Bgee; ENSG00000125734; Expressed in 192 organ(s), highest expression level in left ovary.
DR   ExpressionAtlas; M0R1G1; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR009637; GPR107-like.
DR   PANTHER; PTHR21229; PTHR21229; 1.
DR   Pfam; PF06814; Lung_7-TM_R; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|EPD:M0R1G1,
KW   ECO:0000213|MaxQB:M0R1G1, ECO:0000213|PeptideAtlas:M0R1G1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     27       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        28    331       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5004003742.
FT   TRANSMEM    258    277       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    289    312       Helical. {ECO:0000256|SAM:Phobius}.
FT   NON_TER       1      1       {ECO:0000313|Ensembl:ENSP00000471846}.
SQ   SEQUENCE   331 AA;  36590 MW;  801D7EABA52CBBF6 CRC64;
     XRGLGRGSPA EWGQRLLLVL LLGGCSGRIH QLALTGEKRA DIQLNSFGFY TNGSLEVELS
     VLRLGLREAE EKSLLVGFSL SRVRSGRVRS YSTRDFQDCP LQKNSSSFLV LFLINTKDLQ
     VQVRKYGEQK TLFIFPGLLP EAPSKPGLPK PQATVPRKVD GGGTSAASKP KSTPAVIQGP
     SGKDKDLVLG LSHLNNSYNF SFHVVIGSQA EEGQYSLNFH NCNNSVPGKE HPFDITVMIR
     EKNPDGFLSA AEMPLFKLYM VMSACFLAAG IFWVSILCRN TYSVFKIHWL MAALAFTKSI
     SLLFHSINYY FINSQGHPIE GLAVMYYIAH L
//