ID   M0R0R6_HUMAN            Unreviewed;       158 AA.
AC   M0R0R6;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 8.
DT   16-JAN-2019, entry version 39.
DE   SubName: Full=B-cell receptor CD22 {ECO:0000313|Ensembl:ENSP00000471399};
DE   Flags: Fragment;
GN   Name=CD22 {ECO:0000313|Ensembl:ENSP00000471399};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000471399, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000471399, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000471399}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2013) to UniProtKB.
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DR   EMBL; AC002132; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KC877723; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; U62631; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; M0R0R6; -.
DR   jPOST; M0R0R6; -.
DR   PeptideAtlas; M0R0R6; -.
DR   PRIDE; M0R0R6; -.
DR   Ensembl; ENST00000600424; ENSP00000471399; ENSG00000012124.
DR   UCSC; uc060xbv.1; human.
DR   EuPathDB; HostDB:ENSG00000012124.14; -.
DR   HGNC; HGNC:1643; CD22.
DR   OpenTargets; ENSG00000012124; -.
DR   GeneTree; ENSGT00940000154722; -.
DR   ChiTaRS; CD22; human.
DR   Proteomes; UP000005640; Chromosome 19.
DR   Bgee; ENSG00000012124; Expressed in 176 organ(s), highest expression level in corpus callosum.
DR   ExpressionAtlas; M0R0R6; baseline and differential.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:M0R0R6,
KW   ECO:0000213|PeptideAtlas:M0R0R6};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     19       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        20    158       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5008421112.
FT   DOMAIN       27    134       IGv. {ECO:0000259|Pfam:PF07686}.
FT   NON_TER     158    158       {ECO:0000313|Ensembl:ENSP00000471399}.
SQ   SEQUENCE   158 AA;  18238 MW;  4899E5818CEE39E9 CRC64;
     MHLLGPWLLL LEYLAFSDSS KWVFEHPETL YAWEGACVWI PCTYRALDGD LESFILFHNP
     EYNKNTSKFD GTRLYESTKD GKVPSEQKRV QFLGDKNKNC TLSIHPVHLN DSGQLGLRME
     SKTEKWMERI HLNVSDPPKK VTTVIQNPMP IREGDTVT
//