ID   M0R045_HUMAN            Unreviewed;       334 AA.
AC   M0R045;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   07-NOV-2018, entry version 33.
DE   SubName: Full=Acid phosphatase type 7 {ECO:0000313|Ensembl:ENSP00000470989};
GN   Name=ACP7 {ECO:0000313|Ensembl:ENSP00000470989};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000470989, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000470989, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000470989}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2013) to UniProtKB.
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DR   EMBL; AC011443; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; M0R045; -.
DR   PeptideAtlas; M0R045; -.
DR   PRIDE; M0R045; -.
DR   Ensembl; ENST00000594229; ENSP00000470989; ENSG00000183760.
DR   UCSC; uc010egl.4; human.
DR   EuPathDB; HostDB:ENSG00000183760.10; -.
DR   HGNC; HGNC:33781; ACP7.
DR   OpenTargets; ENSG00000183760; -.
DR   GeneTree; ENSGT00390000015485; -.
DR   Proteomes; UP000005640; Chromosome 19.
DR   Bgee; ENSG00000183760; Expressed in 40 organ(s), highest expression level in right hemisphere of cerebellum.
DR   ExpressionAtlas; M0R045; baseline and differential.
DR   GO; GO:0003993; F:acid phosphatase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   Gene3D; 2.60.40.380; -; 1.
DR   InterPro; IPR039331; PPA-like.
DR   InterPro; IPR008963; Purple_acid_Pase-like_N.
DR   InterPro; IPR015914; Purple_acid_Pase_N.
DR   PANTHER; PTHR22953; PTHR22953; 1.
DR   Pfam; PF16656; Pur_ac_phosph_N; 1.
DR   SUPFAM; SSF49363; SSF49363; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:M0R045,
KW   ECO:0000213|PeptideAtlas:M0R045};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     26       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        27    334       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5004003731.
FT   DOMAIN       32    124       Pur_ac_phosph_N.
FT                                {ECO:0000259|Pfam:PF16656}.
SQ   SEQUENCE   334 AA;  36600 MW;  D6BF707579AB09B9 CRC64;
     MHPLPGYWSC YCLLLLFSLG VQGSLGAPSA APEQVHLSYP GEPGSMTVTW TTWVPTRSEV
     QFGLQPSGPL PLRAQGTFVP FVDGGILRRK LYIHRVTLRK LLPGVQYVYR CGSAQGWSRR
     FRFRALKNGA HWSPRLAVFG DLGADNPKAV PRLRRDTQQG MYDAVLHVAT SLTTRLASAC
     RGIMRACGTA GIWVPPTSSP SPPRSISFSI MAATWYRGSF AGWRATSRKP IRTGQPGRGS
     SLWGTGPCTA PTQIWTTAHD MKARSAKASK ASCTGWRIFS TNMEWICSCG LMSTRMNDCG
     QFTTTRYLTA AERCPTPTRE GLSTSSQDLL MGRS
//