ID   M0QZ01_HUMAN            Unreviewed;       191 AA.
AC   M0QZ01;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   16-JAN-2019, entry version 40.
DE   SubName: Full=B-cell receptor CD22 {ECO:0000313|Ensembl:ENSP00000470193};
GN   Name=CD22 {ECO:0000313|Ensembl:ENSP00000470193};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000470193, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000470193, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000470193}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2013) to UniProtKB.
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DR   EMBL; AC002132; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KC877723; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; U62631; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; M0QZ01; -.
DR   jPOST; M0QZ01; -.
DR   PeptideAtlas; M0QZ01; -.
DR   PRIDE; M0QZ01; -.
DR   Ensembl; ENST00000601769; ENSP00000470193; ENSG00000012124.
DR   UCSC; uc060xby.1; human.
DR   EuPathDB; HostDB:ENSG00000012124.14; -.
DR   HGNC; HGNC:1643; CD22.
DR   OpenTargets; ENSG00000012124; -.
DR   eggNOG; ENOG410IUGI; Eukaryota.
DR   eggNOG; ENOG410YH8H; LUCA.
DR   GeneTree; ENSGT00940000154722; -.
DR   ChiTaRS; CD22; human.
DR   Proteomes; UP000005640; Chromosome 19.
DR   Bgee; ENSG00000012124; Expressed in 176 organ(s), highest expression level in corpus callosum.
DR   ExpressionAtlas; M0QZ01; baseline and differential.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:M0QZ01,
KW   ECO:0000213|PeptideAtlas:M0QZ01};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     19       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        20    191       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5004003723.
FT   DOMAIN       27    134       IGv. {ECO:0000259|Pfam:PF07686}.
SQ   SEQUENCE   191 AA;  21837 MW;  7D5DC9FF11A71C54 CRC64;
     MHLLGPWLLL LEYLAFSDSS KWVFEHPETL YAWEGACVWI PCTYRALDGD LESFILFHNP
     EYNKNTSKFD GTRLYESTKD GKVPSEQKRV QFLGDKNKNC TLSIHPVHLN DSGQLGLRME
     SKTEKWMERI HLNVSVAPRG GSNEAGCCHL DLLDHQVCLH PERAQVLPTV ESPWEDCDLP
     ASGCRWEVPL Q
//