ID   M0QYN1_HUMAN            Unreviewed;       211 AA.
AC   M0QYN1;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   16-JAN-2019, entry version 39.
DE   SubName: Full=IgG receptor FcRn large subunit p51 {ECO:0000313|Ensembl:ENSP00000472604};
DE   Flags: Fragment;
GN   Name=FCGRT {ECO:0000313|Ensembl:ENSP00000472604};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000472604, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000472604, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000213|PubMed:21269460}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA   Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA   Burckstummer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT   "Initial characterization of the human central proteome.";
RL   BMC Syst. Biol. 5:17-17(2011).
RN   [3] {ECO:0000313|Ensembl:ENSP00000472604}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2013) to UniProtKB.
RN   [4] {ECO:0000213|PubMed:25944712}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=25944712;
RA   Vaca Jacome A.S., Rabilloud T., Schaeffer-Reiss C., Rompais M.,
RA   Ayoub D., Lane L., Bairoch A., Van Dorsselaer A., Carapito C.;
RT   "N-terminome analysis of the human mitochondrial proteome.";
RL   Proteomics 15:2519-2524(2015).
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DR   EMBL; AC010619; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; M0QYN1; -.
DR   SMR; M0QYN1; -.
DR   jPOST; M0QYN1; -.
DR   PeptideAtlas; M0QYN1; -.
DR   PRIDE; M0QYN1; -.
DR   Ensembl; ENST00000598319; ENSP00000472604; ENSG00000104870.
DR   UCSC; uc061bfd.1; human.
DR   EuPathDB; HostDB:ENSG00000104870.12; -.
DR   HGNC; HGNC:3621; FCGRT.
DR   OpenTargets; ENSG00000104870; -.
DR   eggNOG; ENOG410IPRY; Eukaryota.
DR   eggNOG; ENOG4111C4R; LUCA.
DR   GeneTree; ENSGT00940000154232; -.
DR   ChiTaRS; FCGRT; human.
DR   Proteomes; UP000005640; Chromosome 19.
DR   Bgee; ENSG00000104870; Expressed in 208 organ(s), highest expression level in mucosa of transverse colon.
DR   ExpressionAtlas; M0QYN1; baseline and differential.
DR   Gene3D; 3.30.500.10; -; 1.
DR   InterPro; IPR011161; MHC_I-like_Ag-recog.
DR   InterPro; IPR037055; MHC_I-like_Ag-recog_sf.
DR   InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR   Pfam; PF00129; MHC_I; 1.
DR   SUPFAM; SSF54452; SSF54452; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:M0QYN1,
KW   ECO:0000213|PeptideAtlas:M0QYN1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     22       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        23    211       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5004005293.
FT   DOMAIN       26    196       MHC_I-like_Ag-recog.
FT                                {ECO:0000259|Pfam:PF00129}.
FT   NON_TER       1      1       {ECO:0000313|Ensembl:ENSP00000472604}.
SQ   SEQUENCE   211 AA;  23800 MW;  DCA5408ADE509C7F CRC64;
     GVPRPQPWAL GLLLFLLPGS LGAESHLSLL YHLTAVSSPA PGTPAFWVSG WLGPQQYLSY
     NSLRGEAEPC GAWVWENQVS WYWEKETTDL RIKEKLFLEA FKALGGKGPY TLQGLLGCEL
     GPDNTSVPTA KFALNGEEFM NFDLKQGTWG GDWPEALAIS QRWQQQDKAA NKELTFLLFS
     CPHRLREHLE RGRGNLEWKE PKARQIFCAW I
//