ID   M0QY05_HUMAN            Unreviewed;       144 AA.
AC   M0QY05;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 8.
DT   16-JAN-2019, entry version 41.
DE   SubName: Full=B-cell receptor CD22 {ECO:0000313|Ensembl:ENSP00000469503};
DE   Flags: Fragment;
GN   Name=CD22 {ECO:0000313|Ensembl:ENSP00000469503};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000469503, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000469503, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000469503}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2013) to UniProtKB.
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DR   EMBL; AC002132; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KC877723; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; U62631; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; M0QY05; -.
DR   jPOST; M0QY05; -.
DR   PeptideAtlas; M0QY05; -.
DR   Ensembl; ENST00000600131; ENSP00000469503; ENSG00000012124.
DR   UCSC; uc060xbk.1; human.
DR   EuPathDB; HostDB:ENSG00000012124.14; -.
DR   HGNC; HGNC:1643; CD22.
DR   OpenTargets; ENSG00000012124; -.
DR   eggNOG; ENOG410IUGI; Eukaryota.
DR   eggNOG; ENOG410YH8H; LUCA.
DR   GeneTree; ENSGT00940000154722; -.
DR   ChiTaRS; CD22; human.
DR   Proteomes; UP000005640; Chromosome 19.
DR   Bgee; ENSG00000012124; Expressed in 176 organ(s), highest expression level in corpus callosum.
DR   ExpressionAtlas; M0QY05; baseline and differential.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:M0QY05,
KW   ECO:0000213|PeptideAtlas:M0QY05};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     19       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        20    144       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5008421110.
FT   DOMAIN       27    134       IGv. {ECO:0000259|Pfam:PF07686}.
FT   NON_TER     144    144       {ECO:0000313|Ensembl:ENSP00000469503}.
SQ   SEQUENCE   144 AA;  16821 MW;  701E0AC002F99060 CRC64;
     MHLLGPWLLL LEYLAFSDSS KWVFEHPETL YAWEGACVWI PCTYRALDGD LESFILFHNP
     EYNKNTSKFD GTRLYESTKD GKVPSEQKRV QFLGDKNKNC TLSIHPVHLN DSGQLGLRME
     SKTEKWMERI HLNVSERPFP PHIQ
//