ID   K9N1J3_HUMAN            Unreviewed;       308 AA.
AC   K9N1J3;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   12-SEP-2018, entry version 41.
DE   SubName: Full=Interleukin 15 receptor alpha isoform IC5 {ECO:0000313|EMBL:AFY11391.1};
DE   SubName: Full=Interleukin-15 receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000380423};
GN   Name=IL15RA {ECO:0000313|Ensembl:ENSP00000380423};
GN   Synonyms=il15ra {ECO:0000313|EMBL:AFY11391.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:AFY11391.1};
RN   [1] {ECO:0000313|Ensembl:ENSP00000380423, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15164054; DOI=10.1038/nature02462;
RA   Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L.,
RA   Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K.,
RA   Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L.,
RA   Taylor A., Battles J., Bird C.P., Ainscough R., Almeida J.P.,
RA   Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J.,
RA   Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J.,
RA   Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D.,
RA   Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S.,
RA   Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L.,
RA   Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S.,
RA   Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L.,
RA   Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J.,
RA   Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M.,
RA   Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S.,
RA   Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M.,
RA   Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A.,
RA   Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T.,
RA   Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I.,
RA   Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T.,
RA   Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M.,
RA   Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W.,
RA   Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H.,
RA   Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L.,
RA   Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K.,
RA   Siebert R., Fechtel K., Bentley D., Durbin R., Hubbard T.,
RA   Doucette-Stamm L., Beck S., Smith D.R., Rogers J.;
RT   "The DNA sequence and comparative analysis of human chromosome 10.";
RL   Nature 429:375-381(2004).
RN   [2] {ECO:0000313|EMBL:AFY11391.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=23074221; DOI=10.1074/jbc.M112.378612;
RA   Muller J.R., Waldmann T.A., Kruhlak M.J., Dubois S.;
RT   "Paracrine and Transpresentation Functions of IL-15 Are Mediated by
RT   Diverse Splice Versions of IL-15R? in Human Monocytes and Dendritic
RT   Cells.";
RL   J. Biol. Chem. 287:40328-40338(2012).
RN   [3] {ECO:0000313|EMBL:AFY11391.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Mueller J., Waldmann T.A., Kruhlak M.J., Dubois S.;
RL   Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN   [4] {ECO:0000313|Ensembl:ENSP00000380423}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2014) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
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DR   EMBL; AL137186; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; JX987308; AFY11391.1; -; mRNA.
DR   UniGene; Hs.445124; -.
DR   PeptideAtlas; K9N1J3; -.
DR   PRIDE; K9N1J3; -.
DR   Ensembl; ENST00000397251; ENSP00000380423; ENSG00000134470.
DR   UCSC; uc057rlo.1; human.
DR   EuPathDB; HostDB:ENSG00000134470.19; -.
DR   HGNC; HGNC:5978; IL15RA.
DR   OpenTargets; ENSG00000134470; -.
DR   eggNOG; ENOG410IWP4; Eukaryota.
DR   eggNOG; ENOG410Z8MM; LUCA.
DR   GeneTree; ENSGT00390000000121; -.
DR   Proteomes; UP000005640; Chromosome 10.
DR   Bgee; ENSG00000134470; Expressed in 158 organ(s), highest expression level in ectocervix.
DR   ExpressionAtlas; K9N1J3; baseline and differential.
DR   CDD; cd00033; CCP; 1.
DR   InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR   InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR   SMART; SM00032; CCP; 1.
DR   SUPFAM; SSF57535; SSF57535; 1.
DR   PROSITE; PS50923; SUSHI; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Disulfide bond {ECO:0000256|SAAS:SAAS00887447};
KW   Proteomics identification {ECO:0000213|MaxQB:K9N1J3,
KW   ECO:0000213|PeptideAtlas:K9N1J3};
KW   Receptor {ECO:0000313|EMBL:AFY11391.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Sushi {ECO:0000256|PROSITE-ProRule:PRU00302}.
FT   SIGNAL        1     30       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        31    308       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5014101199.
FT   DOMAIN       82    146       Sushi. {ECO:0000259|PROSITE:PS50923}.
SQ   SEQUENCE   308 AA;  32833 MW;  C7E16A14649D99E3 CRC64;
     MAPRRARGCR TLGLPALLLL LLLRPPATRD ARDRLAVLAG RSRISESFNH EVQTHEACVR
     LRTMENCPQC HHHRTSRQQA GITCPPPMSV EHADIWVKSY SLYSRERYIC NSGFKRKAGT
     SSLTECVLNK ATNVAHWTTP SLKCIRDPAL VHQRPAPPST VTTAGVTPQP ESLSPSGKEP
     AASSPSSNNT AATTAAIVPG SQLMPSKSPS TGTTEISSHE SSHGTPSQTT AKNWELTASA
     SHQPPGVYPQ GHSDTTVAIS TSTVLLCGLS AVSLLACYLK SSLDAFIKIR GGFSTWLLGL
     PHSTVGSG
//