ID   K7ESM8_HUMAN            Unreviewed;        82 AA.
AC   K7ESM8;
DT   09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 1.
DT   12-SEP-2018, entry version 26.
DE   SubName: Full=Evolutionarily conserved-signaling intermediate in Toll pathway, mitochondrial {ECO:0000313|Ensembl:ENSP00000468783};
GN   Name=ECSIT {ECO:0000313|Ensembl:ENSP00000468783};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000468783, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000468783, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000468783}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2012) to UniProtKB.
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DR   EMBL; AC008481; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; K7ESM8; -.
DR   PeptideAtlas; K7ESM8; -.
DR   Ensembl; ENST00000588998; ENSP00000468783; ENSG00000130159.
DR   UCSC; uc060ttt.1; human.
DR   EuPathDB; HostDB:ENSG00000130159.13; -.
DR   HGNC; HGNC:29548; ECSIT.
DR   OpenTargets; ENSG00000130159; -.
DR   eggNOG; KOG3941; Eukaryota.
DR   eggNOG; ENOG41100I6; LUCA.
DR   GeneTree; ENSGT00390000005147; -.
DR   Proteomes; UP000005640; Chromosome 19.
DR   Bgee; ENSG00000130159; Expressed in 213 organ(s), highest expression level in apex of heart.
DR   ExpressionAtlas; K7ESM8; baseline and differential.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     18       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        19     82       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003900859.
SQ   SEQUENCE   82 AA;  8277 MW;  B7CBABCE24825191 CRC64;
     MSWVQATLLA RGLCRAWGGT CGAALTGTSI SQVPLPKDST GAADPPQPHI VGSGRDAGGV
     EPLLPDAAGP GVCEEWLGQL RV
//