ID   K7ES75_HUMAN            Unreviewed;        88 AA.
AC   K7ES75;
DT   09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 1.
DT   16-JAN-2019, entry version 40.
DE   SubName: Full=Galectin-3-binding protein {ECO:0000313|Ensembl:ENSP00000468586};
DE   Flags: Fragment;
GN   Name=LGALS3BP {ECO:0000313|Ensembl:ENSP00000468586};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000468586, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000468586, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16625196; DOI=10.1038/nature04689;
RA   Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA   Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA   Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA   Chang J.L., Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA   DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R.,
RA   Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N.,
RA   Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B.,
RA   Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J.,
RA   Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E.,
RA   Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J.,
RA   Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C.,
RA   Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA   Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA   Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT   "DNA sequence of human chromosome 17 and analysis of rearrangement in
RT   the human lineage.";
RL   Nature 440:1045-1049(2006).
RN   [2] {ECO:0000213|PubMed:21269460}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA   Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA   Burckstummer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT   "Initial characterization of the human central proteome.";
RL   BMC Syst. Biol. 5:17-17(2011).
RN   [3] {ECO:0000313|Ensembl:ENSP00000468586}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2012) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00196}.
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DR   EMBL; AC100788; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; K7ES75; -.
DR   jPOST; K7ES75; -.
DR   PeptideAtlas; K7ES75; -.
DR   PRIDE; K7ES75; -.
DR   Ensembl; ENST00000591274; ENSP00000468586; ENSG00000108679.
DR   UCSC; uc060kxt.1; human.
DR   EuPathDB; HostDB:ENSG00000108679.12; -.
DR   HGNC; HGNC:6564; LGALS3BP.
DR   OpenTargets; ENSG00000108679; -.
DR   eggNOG; ENOG410IY2Y; Eukaryota.
DR   eggNOG; ENOG410YBYF; LUCA.
DR   GeneTree; ENSGT00940000162516; -.
DR   ChiTaRS; LGALS3BP; human.
DR   Proteomes; UP000005640; Chromosome 17.
DR   Bgee; ENSG00000108679; Expressed in 221 organ(s), highest expression level in heart left ventricle.
DR   ExpressionAtlas; K7ES75; baseline and differential.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   Gene3D; 3.10.250.10; -; 1.
DR   InterPro; IPR001190; SRCR.
DR   InterPro; IPR017448; SRCR-like_dom.
DR   InterPro; IPR036772; SRCR-like_dom_sf.
DR   Pfam; PF00530; SRCR; 1.
DR   PRINTS; PR00258; SPERACTRCPTR.
DR   SMART; SM00202; SR; 1.
DR   SUPFAM; SSF56487; SSF56487; 1.
DR   PROSITE; PS00420; SRCR_1; 1.
DR   PROSITE; PS50287; SRCR_2; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Disulfide bond {ECO:0000256|SAAS:SAAS00873970};
KW   Proteomics identification {ECO:0000213|EPD:K7ES75,
KW   ECO:0000213|MaxQB:K7ES75, ECO:0000213|PeptideAtlas:K7ES75};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     18       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        19     88       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003903319.
FT   DOMAIN       24     88       SRCR. {ECO:0000259|PROSITE:PS50287}.
FT   NON_TER      88     88       {ECO:0000313|Ensembl:ENSP00000468586}.
SQ   SEQUENCE   88 AA;  9490 MW;  A52FFF03DDF710D5 CRC64;
     MTPPRLFWVW LLVAGTQGVN DGDMRLADGG ATNQGRVEIF YRGQWGTVCD NLWDLTDASV
     VCRALGFENA TQALGRAAFG QGSGPIML
//