ID   K7EQH9_HUMAN            Unreviewed;       122 AA.
AC   K7EQH9;
DT   09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 1.
DT   16-JAN-2019, entry version 32.
DE   SubName: Full=Alpha-N-acetylglucosaminidase {ECO:0000313|Ensembl:ENSP00000467836};
DE   Flags: Fragment;
GN   Name=NAGLU {ECO:0000313|Ensembl:ENSP00000467836};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000467836, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000467836, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16625196; DOI=10.1038/nature04689;
RA   Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA   Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA   Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA   Chang J.L., Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA   DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R.,
RA   Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N.,
RA   Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B.,
RA   Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J.,
RA   Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E.,
RA   Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J.,
RA   Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C.,
RA   Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA   Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA   Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT   "DNA sequence of human chromosome 17 and analysis of rearrangement in
RT   the human lineage.";
RL   Nature 440:1045-1049(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000467836}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2012) to UniProtKB.
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DR   EMBL; AC067852; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; K7EQH9; -.
DR   jPOST; K7EQH9; -.
DR   PeptideAtlas; K7EQH9; -.
DR   PRIDE; K7EQH9; -.
DR   Ensembl; ENST00000591587; ENSP00000467836; ENSG00000108784.
DR   UCSC; uc060fjp.1; human.
DR   EuPathDB; HostDB:ENSG00000108784.9; -.
DR   HGNC; HGNC:7632; NAGLU.
DR   OpenTargets; ENSG00000108784; -.
DR   eggNOG; KOG2233; Eukaryota.
DR   eggNOG; ENOG410XNMK; LUCA.
DR   GeneTree; ENSGT00390000005900; -.
DR   ChiTaRS; NAGLU; human.
DR   Proteomes; UP000005640; Chromosome 17.
DR   Bgee; ENSG00000108784; Expressed in 206 organ(s), highest expression level in right lobe of liver.
DR   ExpressionAtlas; K7EQH9; baseline and differential.
DR   InterPro; IPR007781; NAGLU.
DR   InterPro; IPR024733; NAGLU_tim-barrel.
DR   PANTHER; PTHR12872; PTHR12872; 1.
DR   Pfam; PF05089; NAGLU; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:K7EQH9};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     22       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        23    122       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003900898.
FT   DOMAIN       41    119       NAGLU. {ECO:0000259|Pfam:PF05089}.
FT   NON_TER       1      1       {ECO:0000313|Ensembl:ENSP00000467836}.
SQ   SEQUENCE   122 AA;  13165 MW;  76E0D61542A3E0E8 CRC64;
     RGAAPLPARL LWLPRGLVRL SAAPAAATAS RAGGADRGHA QQVYLALGLT QAEINEFFTG
     PAFLAWGRMG NLHTWDGPLP PSWHIKQLYL QHRVLDQMRS FGMTPVLPAF AGHVPEAVTS
     GY
//