ID   K7EPM0_HUMAN            Unreviewed;        89 AA.
AC   K7EPM0;
DT   09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 2.
DT   05-DEC-2018, entry version 27.
DE   SubName: Full=Phylloquinone omega-hydroxylase CYP4F2 {ECO:0000313|Ensembl:ENSP00000467443};
GN   Name=CYP4F2 {ECO:0000313|Ensembl:ENSP00000467443};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000467443, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000467443, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000467443}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2012) to UniProtKB.
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DR   EMBL; AC004791; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC005336; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF459709; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PeptideAtlas; K7EPM0; -.
DR   Ensembl; ENST00000587671; ENSP00000467443; ENSG00000186115.
DR   UCSC; uc060uwb.1; human.
DR   EuPathDB; HostDB:ENSG00000186115.12; -.
DR   HGNC; HGNC:2645; CYP4F2.
DR   OpenTargets; ENSG00000186115; -.
DR   eggNOG; KOG0157; Eukaryota.
DR   eggNOG; COG2124; LUCA.
DR   GeneTree; ENSGT00940000154646; -.
DR   Proteomes; UP000005640; Chromosome 19.
DR   Bgee; ENSG00000186115; Expressed in 88 organ(s), highest expression level in caput epididymis.
DR   ExpressionAtlas; K7EPM0; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     16       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        17     89       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003900864.
FT   TRANSMEM     20     42       Helical. {ECO:0000256|SAM:Phobius}.
SQ   SEQUENCE   89 AA;  10202 MW;  2295F1E138360EE6 CRC64;
     MSQLSLSWLG LWPVAASPWL LLLLVGASWL LAHVLAWTYA FYDNCRRLRC FPQPPRRNWF
     WGHQGMLPLH QRTSSSTASW SPGWGMGSC
//