ID   K7ENX5_HUMAN            Unreviewed;       170 AA.
AC   K7ENX5;
DT   09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 1.
DT   16-JAN-2019, entry version 29.
DE   SubName: Full=Alpha-N-acetylglucosaminidase {ECO:0000313|Ensembl:ENSP00000467135};
DE   Flags: Fragment;
GN   Name=NAGLU {ECO:0000313|Ensembl:ENSP00000467135};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000467135, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000467135, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16625196; DOI=10.1038/nature04689;
RA   Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA   Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA   Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA   Chang J.L., Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA   DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R.,
RA   Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N.,
RA   Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B.,
RA   Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J.,
RA   Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E.,
RA   Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J.,
RA   Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C.,
RA   Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA   Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA   Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT   "DNA sequence of human chromosome 17 and analysis of rearrangement in
RT   the human lineage.";
RL   Nature 440:1045-1049(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000467135}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2012) to UniProtKB.
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DR   EMBL; AC067852; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; K7ENX5; -.
DR   jPOST; K7ENX5; -.
DR   PeptideAtlas; K7ENX5; -.
DR   PRIDE; K7ENX5; -.
DR   Ensembl; ENST00000586516; ENSP00000467135; ENSG00000108784.
DR   UCSC; uc060fjo.1; human.
DR   EuPathDB; HostDB:ENSG00000108784.9; -.
DR   HGNC; HGNC:7632; NAGLU.
DR   OpenTargets; ENSG00000108784; -.
DR   eggNOG; KOG2233; Eukaryota.
DR   eggNOG; ENOG410XNMK; LUCA.
DR   GeneTree; ENSGT00390000005900; -.
DR   ChiTaRS; NAGLU; human.
DR   Proteomes; UP000005640; Chromosome 17.
DR   Bgee; ENSG00000108784; Expressed in 206 organ(s), highest expression level in right lobe of liver.
DR   ExpressionAtlas; K7ENX5; baseline and differential.
DR   InterPro; IPR007781; NAGLU.
DR   InterPro; IPR024733; NAGLU_tim-barrel.
DR   PANTHER; PTHR12872; PTHR12872; 1.
DR   Pfam; PF05089; NAGLU; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:K7ENX5,
KW   ECO:0000213|PeptideAtlas:K7ENX5};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     25       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        26    170       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003900804.
FT   DOMAIN       44    169       NAGLU. {ECO:0000259|Pfam:PF05089}.
FT   NON_TER       1      1       {ECO:0000313|Ensembl:ENSP00000467135}.
FT   NON_TER     170    170       {ECO:0000313|Ensembl:ENSP00000467135}.
SQ   SEQUENCE   170 AA;  18653 MW;  186E75E41EB49D96 CRC64;
     XGRRGAAPLP ARLLWLPRGL VRLSAAPAAA TASRAGGADR GHAQQVYLAL GLTQAEINEF
     FTGPAFLAWG RMGNLHTWDG PLPPSWHIKQ LYLQHRVLDQ MRSFGMTPVL PAFAGHVPEA
     VTRVFPQVNV TKMGSWGHFN CSYSCSFLLA PEDPIFPIIG SLFLRELIKE
//