ID   K7ENL4_HUMAN            Unreviewed;       132 AA.
AC   K7ENL4;
DT   09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 1.
DT   16-JAN-2019, entry version 34.
DE   RecName: Full=Golgi apparatus membrane protein TVP23 homolog {ECO:0000256|RuleBase:RU361206};
DE   Flags: Fragment;
GN   Name=TVP23B {ECO:0000313|Ensembl:ENSP00000467001};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000467001, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000467001, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16625196; DOI=10.1038/nature04689;
RA   Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA   Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA   Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA   Chang J.L., Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA   DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R.,
RA   Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N.,
RA   Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B.,
RA   Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J.,
RA   Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E.,
RA   Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J.,
RA   Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C.,
RA   Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA   Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA   Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT   "DNA sequence of human chromosome 17 and analysis of rearrangement in
RT   the human lineage.";
RL   Nature 440:1045-1049(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000467001}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2012) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU361206};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU361206}.
CC   -!- SIMILARITY: Belongs to the TVP23 family.
CC       {ECO:0000256|RuleBase:RU361206}.
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DR   EMBL; AC107982; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; K7ENL4; -.
DR   jPOST; K7ENL4; -.
DR   MaxQB; K7ENL4; -.
DR   PeptideAtlas; K7ENL4; -.
DR   PRIDE; K7ENL4; -.
DR   Ensembl; ENST00000575261; ENSP00000467001; ENSG00000171928.
DR   UCSC; uc060cgl.1; human.
DR   EuPathDB; HostDB:ENSG00000171928.13; -.
DR   HGNC; HGNC:20399; TVP23B.
DR   OpenTargets; ENSG00000171928; -.
DR   eggNOG; KOG3195; Eukaryota.
DR   eggNOG; ENOG4111GAN; LUCA.
DR   GeneTree; ENSGT00390000004428; -.
DR   Proteomes; UP000005640; Chromosome 17.
DR   Bgee; ENSG00000171928; Expressed in 98 organ(s), highest expression level in ectocervix.
DR   ExpressionAtlas; K7ENL4; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR008564; TVP23-like.
DR   PANTHER; PTHR13019; PTHR13019; 1.
DR   Pfam; PF05832; DUF846; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|RuleBase:RU361206};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|RuleBase:RU361206};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361206}.
FT   SIGNAL        1     20       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        21    132       Golgi apparatus membrane protein TVP23
FT                                homolog. {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003903225.
FT   TRANSMEM     62     83       Helical. {ECO:0000256|RuleBase:RU361206}.
FT   TRANSMEM     89    108       Helical. {ECO:0000256|RuleBase:RU361206}.
FT   NON_TER     132    132       {ECO:0000313|Ensembl:ENSP00000467001}.
SQ   SEQUENCE   132 AA;  15323 MW;  07B2008A202DD3FB CRC64;
     MVTIILLLSC DFWAVKNVTG RLMVGLRWWN HIDEDGKSHW VFESRKESSQ ENKTVSEAES
     RIFWLGLIAC PVLWVIFAFS ALFSFRVKWL AVVIMGVVLQ GANLYGYIRC KVRSRKHLTS
     MATSYFGKQF LR
//