ID   K7EMT8_HUMAN            Unreviewed;       110 AA.
AC   K7EMT8;
DT   09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 1.
DT   16-JAN-2019, entry version 34.
DE   SubName: Full=Sterol regulatory element-binding protein 1 {ECO:0000313|Ensembl:ENSP00000466643};
DE   Flags: Fragment;
GN   Name=SREBF1 {ECO:0000313|Ensembl:ENSP00000466643};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000466643, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000466643, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16625196; DOI=10.1038/nature04689;
RA   Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA   Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA   Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA   Chang J.L., Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA   DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R.,
RA   Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N.,
RA   Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B.,
RA   Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J.,
RA   Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E.,
RA   Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J.,
RA   Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C.,
RA   Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA   Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA   Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT   "DNA sequence of human chromosome 17 and analysis of rearrangement in
RT   the human lineage.";
RL   Nature 440:1045-1049(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000466643}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2012) to UniProtKB.
RN   [3] {ECO:0000213|PubMed:23186163}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=23186163;
RA   Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J.,
RA   Mohammed S.;
RT   "Toward a comprehensive characterization of a human cancer cell
RT   phosphoproteome.";
RL   J. Proteome Res. 12:260-271(2013).
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DR   EMBL; AC122129; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; K7EMT8; -.
DR   jPOST; K7EMT8; -.
DR   PeptideAtlas; K7EMT8; -.
DR   PRIDE; K7EMT8; -.
DR   Ensembl; ENST00000485080; ENSP00000466643; ENSG00000072310.
DR   UCSC; uc060bxv.1; human.
DR   EuPathDB; HostDB:ENSG00000072310.16; -.
DR   HGNC; HGNC:11289; SREBF1.
DR   OpenTargets; ENSG00000072310; -.
DR   eggNOG; KOG2588; Eukaryota.
DR   eggNOG; ENOG410XSVP; LUCA.
DR   GeneTree; ENSGT00940000159156; -.
DR   ChiTaRS; SREBF1; human.
DR   Proteomes; UP000005640; Chromosome 17.
DR   Bgee; ENSG00000072310; Expressed in 188 organ(s), highest expression level in right adrenal gland.
DR   ExpressionAtlas; K7EMT8; baseline and differential.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR024097; bHLH_ZIP_TF.
DR   PANTHER; PTHR12565; PTHR12565; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:K7EMT8};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     18       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        19    110       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003900764.
FT   NON_TER       1      1       {ECO:0000313|Ensembl:ENSP00000466643}.
SQ   SEQUENCE   110 AA;  12017 MW;  73658829E5D5A20C CRC64;
     AVQLFLCDLL LVVRTSLWRQ QQPPAPAPAA QGTSSRPQAS ALELRGFQRD LSSLRRLAQS
     FRPAMRRVFL HEATARLMAG ASPTRTHQLL DRSLRRRAGP GGKGADGCAD
//