ID   K7EMK9_HUMAN            Unreviewed;       178 AA.
AC   K7EMK9;
DT   09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 2.
DT   16-JAN-2019, entry version 37.
DE   SubName: Full=Phospholipid phosphatase 2 {ECO:0000313|Ensembl:ENSP00000466545};
DE   Flags: Fragment;
GN   Name=PLPP2 {ECO:0000313|Ensembl:ENSP00000466545};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000466545, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000466545, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000466545}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2012) to UniProtKB.
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DR   EMBL; AC016588; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EPD; K7EMK9; -.
DR   jPOST; K7EMK9; -.
DR   PeptideAtlas; K7EMK9; -.
DR   PRIDE; K7EMK9; -.
DR   Ensembl; ENST00000591572; ENSP00000466545; ENSG00000141934.
DR   UCSC; uc060qnl.1; human.
DR   EuPathDB; HostDB:ENSG00000141934.9; -.
DR   HGNC; HGNC:9230; PLPP2.
DR   OpenTargets; ENSG00000141934; -.
DR   eggNOG; KOG3030; Eukaryota.
DR   eggNOG; COG0671; LUCA.
DR   GeneTree; ENSGT00940000155885; -.
DR   ChiTaRS; PLPP2; human.
DR   Proteomes; UP000005640; Chromosome 19.
DR   Bgee; ENSG00000141934; Expressed in 147 organ(s), highest expression level in minor salivary gland.
DR   ExpressionAtlas; K7EMK9; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008195; F:phosphatidate phosphatase activity; IEA:InterPro.
DR   InterPro; IPR028674; LPP2.
DR   InterPro; IPR036938; P_Acid_Pase_2/haloperoxi_sf.
DR   InterPro; IPR000326; P_Acid_Pase_2/haloperoxidase.
DR   PANTHER; PTHR10165:SF25; PTHR10165:SF25; 1.
DR   Pfam; PF01569; PAP2; 1.
DR   SUPFAM; SSF48317; SSF48317; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|MaxQB:K7EMK9,
KW   ECO:0000213|PeptideAtlas:K7EMK9};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     20       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        21    178       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003903199.
FT   TRANSMEM     62     84       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     96    115       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      107    177       acidPPc. {ECO:0000259|Pfam:PF01569}.
FT   NON_TER     178    178       {ECO:0000313|Ensembl:ENSP00000466545}.
SQ   SEQUENCE   178 AA;  19766 MW;  7740A924CAB04F01 CRC64;
     MQRRWVFVLL DVLCLLVGFS SPPASLPFAI LTLVNAPYKR GFYCGDDSIR YPYRPDTITH
     GLMAGVTITA TVILVSAGEA YLVYTDRLYS RSDFNNYVAA VYKVLGTFLF GAAVSQSLTD
     LAKYMIGRLR PNFLAVCDPD WSRVNCSVYV QLEKVCRGNP ADVTEARLSF YSGHSSFG
//