ID   K7EK04_HUMAN            Unreviewed;       206 AA.
AC   K7EK04;
DT   09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 1.
DT   13-FEB-2019, entry version 41.
DE   SubName: Full=Pleckstrin homology domain-containing family H member 3 {ECO:0000313|Ensembl:ENSP00000465400};
DE   Flags: Fragment;
GN   Name=PLEKHH3 {ECO:0000313|Ensembl:ENSP00000465400};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000465400, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000465400, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16625196; DOI=10.1038/nature04689;
RA   Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA   Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA   Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA   Chang J.L., Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA   DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R.,
RA   Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N.,
RA   Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B.,
RA   Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J.,
RA   Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E.,
RA   Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J.,
RA   Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C.,
RA   Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA   Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA   Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT   "DNA sequence of human chromosome 17 and analysis of rearrangement in
RT   the human lineage.";
RL   Nature 440:1045-1049(2006).
RN   [2] {ECO:0000213|PubMed:18669648}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=18669648; DOI=10.1073/pnas.0805139105;
RA   Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,
RA   Elledge S.J., Gygi S.P.;
RT   "A quantitative atlas of mitotic phosphorylation.";
RL   Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
RN   [3] {ECO:0000313|Ensembl:ENSP00000465400}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2012) to UniProtKB.
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DR   EMBL; AC067852; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; K7EK04; -.
DR   SwissPalm; K7EK04; -.
DR   EPD; K7EK04; -.
DR   PeptideAtlas; K7EK04; -.
DR   PRIDE; K7EK04; -.
DR   Ensembl; ENST00000587627; ENSP00000465400; ENSG00000068137.
DR   UCSC; uc060fls.1; human.
DR   EuPathDB; HostDB:ENSG00000068137.14; -.
DR   HGNC; HGNC:26105; PLEKHH3.
DR   OpenTargets; ENSG00000068137; -.
DR   GeneTree; ENSGT00940000159764; -.
DR   ChiTaRS; PLEKHH3; human.
DR   Proteomes; UP000005640; Chromosome 17.
DR   Bgee; ENSG00000068137; Expressed in 154 organ(s), highest expression level in body of pancreas.
DR   ExpressionAtlas; K7EK04; baseline and differential.
DR   InterPro; IPR040105; PKHH1/2/3.
DR   PANTHER; PTHR22903; PTHR22903; 2.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:K7EK04,
KW   ECO:0000213|PeptideAtlas:K7EK04};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     18       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        19    206       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003900705.
FT   NON_TER     206    206       {ECO:0000313|Ensembl:ENSP00000465400}.
SQ   SEQUENCE   206 AA;  22728 MW;  343FF3A32FA48B74 CRC64;
     MPLPGGLWWL LCCRRGFTLL HRDYGDGELS GDGDEDEDEE TFELRTPSPA GGGRGGSVEE
     GKMRRRGCLG AWQNELTSPV SKMGKLRPGD GKRLAQGSTG PLEVTLTQPV RSGPVSNRLQ
     SWEETWSLIP EKGLPEDDPD IVVKGWLYRE PRGGGARPWL PPRRAWFVLT RDSLDQFSSS
     GKGARRLGSL VLTSLCSVTG PERRRK
//