ID   K7EJY8_HUMAN            Unreviewed;       144 AA.
AC   K7EJY8;
DT   09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 1.
DT   16-JAN-2019, entry version 40.
DE   SubName: Full=Galectin-3-binding protein {ECO:0000313|Ensembl:ENSP00000465380};
DE   Flags: Fragment;
GN   Name=LGALS3BP {ECO:0000313|Ensembl:ENSP00000465380};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000465380, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000465380, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16625196; DOI=10.1038/nature04689;
RA   Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA   Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA   Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA   Chang J.L., Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA   DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R.,
RA   Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N.,
RA   Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B.,
RA   Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J.,
RA   Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E.,
RA   Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J.,
RA   Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C.,
RA   Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA   Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA   Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT   "DNA sequence of human chromosome 17 and analysis of rearrangement in
RT   the human lineage.";
RL   Nature 440:1045-1049(2006).
RN   [2] {ECO:0000213|PubMed:21269460}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA   Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA   Burckstummer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT   "Initial characterization of the human central proteome.";
RL   BMC Syst. Biol. 5:17-17(2011).
RN   [3] {ECO:0000313|Ensembl:ENSP00000465380}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2012) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00196}.
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DR   EMBL; AC100788; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; K7EJY8; -.
DR   jPOST; K7EJY8; -.
DR   PeptideAtlas; K7EJY8; -.
DR   PRIDE; K7EJY8; -.
DR   Ensembl; ENST00000589906; ENSP00000465380; ENSG00000108679.
DR   UCSC; uc060kxo.1; human.
DR   EuPathDB; HostDB:ENSG00000108679.12; -.
DR   HGNC; HGNC:6564; LGALS3BP.
DR   OpenTargets; ENSG00000108679; -.
DR   eggNOG; ENOG410IY2Y; Eukaryota.
DR   eggNOG; ENOG410YBYF; LUCA.
DR   GeneTree; ENSGT00940000162516; -.
DR   ChiTaRS; LGALS3BP; human.
DR   Proteomes; UP000005640; Chromosome 17.
DR   Bgee; ENSG00000108679; Expressed in 221 organ(s), highest expression level in heart left ventricle.
DR   ExpressionAtlas; K7EJY8; baseline and differential.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   Gene3D; 3.10.250.10; -; 1.
DR   InterPro; IPR001190; SRCR.
DR   InterPro; IPR017448; SRCR-like_dom.
DR   InterPro; IPR036772; SRCR-like_dom_sf.
DR   Pfam; PF00530; SRCR; 1.
DR   PRINTS; PR00258; SPERACTRCPTR.
DR   SMART; SM00202; SR; 1.
DR   SUPFAM; SSF56487; SSF56487; 1.
DR   PROSITE; PS50287; SRCR_2; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00196,
KW   ECO:0000256|SAAS:SAAS00873970};
KW   Proteomics identification {ECO:0000213|EPD:K7EJY8,
KW   ECO:0000213|MaxQB:K7EJY8, ECO:0000213|PeptideAtlas:K7EJY8};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     18       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        19    144       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003900771.
FT   DOMAIN       18     60       SRCR. {ECO:0000259|PROSITE:PS50287}.
FT   DISULFID     29     39       {ECO:0000256|PROSITE-ProRule:PRU00196}.
FT   NON_TER     144    144       {ECO:0000313|Ensembl:ENSP00000465380}.
SQ   SEQUENCE   144 AA;  15611 MW;  E0840D02AB14BB86 CRC64;
     MTPPRLFWVW LLVAGTQGSG PIMLDEVQCT GTEASLADCK SLGWLKSNCR HERDAGVVCT
     NETRSTHTLD LSRELSEALG QIFDSQRGCD LSISVNVQGE DALGFCGHTV ILTANLEAQA
     LWKEPGSNVT MSVDAECVPM VRDL
//