ID   J3QRQ4_HUMAN            Unreviewed;       132 AA.
AC   J3QRQ4;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   12-SEP-2018, entry version 36.
DE   SubName: Full=CD226 antigen {ECO:0000313|Ensembl:ENSP00000464334};
DE   Flags: Fragment;
GN   Name=CD226 {ECO:0000313|Ensembl:ENSP00000464334};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000464334, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000464334, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16177791; DOI=10.1038/nature03983;
RA   Nusbaum C., Zody M.C., Borowsky M.L., Kamal M., Kodira C.D.,
RA   Taylor T.D., Whittaker C.A., Chang J.L., Cuomo C.A., Dewar K.,
RA   FitzGerald M.G., Yang X., Abouelleil A., Allen N.R., Anderson S.,
RA   Bloom T., Bugalter B., Butler J., Cook A., DeCaprio D., Engels R.,
RA   Garber M., Gnirke A., Hafez N., Hall J.L., Norman C.H., Itoh T.,
RA   Jaffe D.B., Kuroki Y., Lehoczky J., Lui A., Macdonald P., Mauceli E.,
RA   Mikkelsen T.S., Naylor J.W., Nicol R., Nguyen C., Noguchi H.,
RA   O'Leary S.B., O'Neill K., Piqani B., Smith C.L., Talamas J.A.,
RA   Topham K., Totoki Y., Toyoda A., Wain H.M., Young S.K., Zeng Q.,
RA   Zimmer A.R., Fujiyama A., Hattori M., Birren B.W., Sakaki Y.,
RA   Lander E.S.;
RT   "DNA sequence and analysis of human chromosome 18.";
RL   Nature 437:551-555(2005).
RN   [2] {ECO:0000313|Ensembl:ENSP00000464334}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (AUG-2012) to UniProtKB.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AC011930; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC090231; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC091137; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; J3QRQ4; -.
DR   PeptideAtlas; J3QRQ4; -.
DR   PRIDE; J3QRQ4; -.
DR   Ensembl; ENST00000583955; ENSP00000464334; ENSG00000150637.
DR   UCSC; uc060pzh.1; human.
DR   EuPathDB; HostDB:ENSG00000150637.8; -.
DR   HGNC; HGNC:16961; CD226.
DR   OpenTargets; ENSG00000150637; -.
DR   eggNOG; ENOG410IDXC; Eukaryota.
DR   eggNOG; ENOG41129MS; LUCA.
DR   GeneTree; ENSGT00500000044993; -.
DR   ChiTaRS; CD226; human.
DR   Proteomes; UP000005640; Chromosome 18.
DR   Bgee; ENSG00000150637; Expressed in 108 organ(s), highest expression level in leukocyte.
DR   ExpressionAtlas; J3QRQ4; baseline and differential.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:J3QRQ4,
KW   ECO:0000213|PeptideAtlas:J3QRQ4};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     18       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        19    132       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003777343.
FT   DOMAIN        4    110       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   NON_TER     132    132       {ECO:0000313|Ensembl:ENSP00000464334}.
SQ   SEQUENCE   132 AA;  15187 MW;  410D9E6B55EA932A CRC64;
     MDYPTLLLAL LHVYRALCEE VLWHTSVPFA ENMSLECVYP SMGILTQVEW FKIGTQQDSI
     AIFSPTHGMV IRKPYAERVY FLNSTMASNN MTLFFRNASE DDVGYYSCSL YTYPQGTWQK
     VIQVVQSDSF EA
//