ID   J3QRF5_HUMAN            Unreviewed;       101 AA.
AC   J3QRF5;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   05-DEC-2018, entry version 39.
DE   SubName: Full=Neuropilin and tolloid-like protein 1 {ECO:0000313|Ensembl:ENSP00000464188};
DE   Flags: Fragment;
GN   Name=NETO1 {ECO:0000313|Ensembl:ENSP00000464188};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000464188, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000464188, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16177791; DOI=10.1038/nature03983;
RA   Nusbaum C., Zody M.C., Borowsky M.L., Kamal M., Kodira C.D.,
RA   Taylor T.D., Whittaker C.A., Chang J.L., Cuomo C.A., Dewar K.,
RA   FitzGerald M.G., Yang X., Abouelleil A., Allen N.R., Anderson S.,
RA   Bloom T., Bugalter B., Butler J., Cook A., DeCaprio D., Engels R.,
RA   Garber M., Gnirke A., Hafez N., Hall J.L., Norman C.H., Itoh T.,
RA   Jaffe D.B., Kuroki Y., Lehoczky J., Lui A., Macdonald P., Mauceli E.,
RA   Mikkelsen T.S., Naylor J.W., Nicol R., Nguyen C., Noguchi H.,
RA   O'Leary S.B., O'Neill K., Piqani B., Smith C.L., Talamas J.A.,
RA   Topham K., Totoki Y., Toyoda A., Wain H.M., Young S.K., Zeng Q.,
RA   Zimmer A.R., Fujiyama A., Hattori M., Birren B.W., Sakaki Y.,
RA   Lander E.S.;
RT   "DNA sequence and analysis of human chromosome 18.";
RL   Nature 437:551-555(2005).
RN   [2] {ECO:0000313|Ensembl:ENSP00000464188}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (AUG-2012) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00059}.
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DR   EMBL; AC023301; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC091138; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; J3QRF5; -.
DR   PeptideAtlas; J3QRF5; -.
DR   PRIDE; J3QRF5; -.
DR   Ensembl; ENST00000579169; ENSP00000464188; ENSG00000166342.
DR   UCSC; uc060qar.1; human.
DR   EuPathDB; HostDB:ENSG00000166342.18; -.
DR   HGNC; HGNC:13823; NETO1.
DR   OpenTargets; ENSG00000166342; -.
DR   eggNOG; ENOG410IJXA; Eukaryota.
DR   eggNOG; ENOG410ZS19; LUCA.
DR   GeneTree; ENSGT00940000156700; -.
DR   Proteomes; UP000005640; Chromosome 18.
DR   Bgee; ENSG00000166342; Expressed in 89 organ(s), highest expression level in caudate nucleus.
DR   ExpressionAtlas; J3QRF5; baseline and differential.
DR   GO; GO:0048168; P:regulation of neuronal synaptic plasticity; IEA:InterPro.
DR   CDD; cd00041; CUB; 1.
DR   Gene3D; 2.60.120.290; -; 1.
DR   InterPro; IPR000859; CUB_dom.
DR   InterPro; IPR028867; NETO1.
DR   InterPro; IPR035914; Sperma_CUB_dom_sf.
DR   PANTHER; PTHR44143:SF1; PTHR44143:SF1; 1.
DR   Pfam; PF00431; CUB; 1.
DR   SUPFAM; SSF49854; SSF49854; 1.
DR   PROSITE; PS01180; CUB; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00059,
KW   ECO:0000256|SAAS:SAAS01008102};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:J3QRF5};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     18       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        19    101       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003776528.
FT   DOMAIN       37    101       CUB. {ECO:0000259|PROSITE:PS01180}.
FT   DISULFID     37     64       {ECO:0000256|PROSITE-ProRule:PRU00059}.
FT   NON_TER     101    101       {ECO:0000313|Ensembl:ENSP00000464188}.
SQ   SEQUENCE   101 AA;  11540 MW;  692735A0D069537C CRC64;
     MSLYGFVASL IILHLSGATK KGTEKQTTSE TQKSVQCGTW TKHAEGGIFT SPNYPSKYPP
     DRECIYIIEA APRQCIELYF DEKYSIEPSW ECKFDHIEVR D
//