ID   J3QQN3_HUMAN            Unreviewed;       145 AA.
AC   J3QQN3;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   05-DEC-2018, entry version 34.
DE   SubName: Full=G-protein-coupled receptor family C group 5 member C {ECO:0000313|Ensembl:ENSP00000463813};
DE   Flags: Fragment;
GN   Name=GPRC5C {ECO:0000313|Ensembl:ENSP00000463813};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000463813, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000463813, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16625196; DOI=10.1038/nature04689;
RA   Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA   Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA   Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA   Chang J.L., Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA   DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R.,
RA   Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N.,
RA   Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B.,
RA   Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J.,
RA   Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E.,
RA   Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J.,
RA   Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C.,
RA   Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA   Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA   Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT   "DNA sequence of human chromosome 17 and analysis of rearrangement in
RT   the human lineage.";
RL   Nature 440:1045-1049(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000463813}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (AUG-2012) to UniProtKB.
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DR   EMBL; AC079325; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; J3QQN3; -.
DR   PeptideAtlas; J3QQN3; -.
DR   Ensembl; ENST00000582444; ENSP00000463813; ENSG00000170412.
DR   UCSC; uc060jof.1; human.
DR   EuPathDB; HostDB:ENSG00000170412.16; -.
DR   HGNC; HGNC:13309; GPRC5C.
DR   OpenTargets; ENSG00000170412; -.
DR   eggNOG; ENOG410IEI6; Eukaryota.
DR   eggNOG; ENOG4110E9P; LUCA.
DR   GeneTree; ENSGT00940000153682; -.
DR   ChiTaRS; GPRC5C; human.
DR   Proteomes; UP000005640; Chromosome 17.
DR   Bgee; ENSG00000170412; Expressed in 172 organ(s), highest expression level in body of stomach.
DR   ExpressionAtlas; J3QQN3; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR   InterPro; IPR017978; GPCR_3_C.
DR   Pfam; PF00003; 7tm_3; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     23       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        24    145       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003777177.
FT   TRANSMEM     47     73       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     85    109       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    121    144       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       65    142       G_PROTEIN_RECEP_F3_4.
FT                                {ECO:0000259|Pfam:PF00003}.
FT   NON_TER     145    145       {ECO:0000313|Ensembl:ENSP00000463813}.
SQ   SEQUENCE   145 AA;  15549 MW;  2C2DA5E39DF6CA06 CRC64;
     MAIHKALVMC LGLPLFLFPG AWAQGHVPPG CSQGLNPLYY NLCDRSGAWG IVLEAVAGAG
     IVTTFVLTII LVASLPFVQD TKKRSLLGTQ VFFLLGTLGL FCLVFACVVK PDFSTCASRR
     FLFGVLFAIC FSCLAAHVFA LNFLA
//