ID   J3QL63_HUMAN            Unreviewed;       141 AA.
AC   J3QL63;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 2.
DT   16-JAN-2019, entry version 45.
DE   RecName: Full=Golgi apparatus membrane protein TVP23 homolog {ECO:0000256|RuleBase:RU361206};
GN   Name=TVP23B {ECO:0000313|Ensembl:ENSP00000463400};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000463400, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000463400, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16625196; DOI=10.1038/nature04689;
RA   Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA   Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA   Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA   Chang J.L., Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA   DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R.,
RA   Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N.,
RA   Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B.,
RA   Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J.,
RA   Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E.,
RA   Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J.,
RA   Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C.,
RA   Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA   Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA   Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT   "DNA sequence of human chromosome 17 and analysis of rearrangement in
RT   the human lineage.";
RL   Nature 440:1045-1049(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000463400}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (AUG-2012) to UniProtKB.
RN   [3] {ECO:0000313|Ensembl:ENSP00000465872}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2012) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU361206};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU361206}.
CC   -!- SIMILARITY: Belongs to the TVP23 family.
CC       {ECO:0000256|RuleBase:RU361206}.
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DR   EMBL; AC107982; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_001303848.1; NM_001316919.1.
DR   RefSeq; NP_001303849.1; NM_001316920.1.
DR   RefSeq; NP_001303850.1; NM_001316921.1.
DR   UniGene; Hs.87295; -.
DR   jPOST; J3QL63; -.
DR   MaxQB; J3QL63; -.
DR   PeptideAtlas; J3QL63; -.
DR   PRIDE; J3QL63; -.
DR   Ensembl; ENST00000476139; ENSP00000463400; ENSG00000171928.
DR   Ensembl; ENST00000581733; ENSP00000465872; ENSG00000171928.
DR   GeneID; 51030; -.
DR   UCSC; uc060cgn.1; human.
DR   CTD; 51030; -.
DR   EuPathDB; HostDB:ENSG00000171928.13; -.
DR   HGNC; HGNC:20399; TVP23B.
DR   OpenTargets; ENSG00000171928; -.
DR   eggNOG; KOG3195; Eukaryota.
DR   eggNOG; ENOG4111GAN; LUCA.
DR   GeneTree; ENSGT00390000004428; -.
DR   OrthoDB; 1356321at2759; -.
DR   GenomeRNAi; 51030; -.
DR   Proteomes; UP000005640; Chromosome 17.
DR   Bgee; ENSG00000171928; Expressed in 98 organ(s), highest expression level in ectocervix.
DR   ExpressionAtlas; J3QL63; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR008564; TVP23-like.
DR   PANTHER; PTHR13019; PTHR13019; 1.
DR   Pfam; PF05832; DUF846; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|RuleBase:RU361206};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|RuleBase:RU361206};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361206}.
FT   SIGNAL        1     20       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        21    141       Golgi apparatus membrane protein TVP23
FT                                homolog. {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5014098607.
FT   TRANSMEM     62     83       Helical. {ECO:0000256|RuleBase:RU361206}.
FT   TRANSMEM     89    108       Helical. {ECO:0000256|RuleBase:RU361206}.
SQ   SEQUENCE   141 AA;  16270 MW;  6E2750BA7C7E5DF9 CRC64;
     MVTIILLLSC DFWAVKNVTG RLMVGLRWWN HIDEDGKSHW VFESRKESSQ ENKTVSEAES
     RIFWLGLIAC PVLWVIFAFS ALFSFRVKWL AVVIMGVVLQ GANLYGYIRC KVRSRKHLTS
     MATSYFGKQF LRQNTGDDQT S
//