ID   J3QL47_HUMAN            Unreviewed;       141 AA.
AC   J3QL47;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   16-JAN-2019, entry version 37.
DE   RecName: Full=Golgi apparatus membrane protein TVP23 homolog {ECO:0000256|RuleBase:RU361206};
GN   Name=TVP23C {ECO:0000313|Ensembl:ENSP00000463371};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000463371, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000463371, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16625196; DOI=10.1038/nature04689;
RA   Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA   Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA   Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA   Chang J.L., Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA   DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R.,
RA   Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N.,
RA   Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B.,
RA   Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J.,
RA   Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E.,
RA   Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J.,
RA   Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C.,
RA   Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA   Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA   Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT   "DNA sequence of human chromosome 17 and analysis of rearrangement in
RT   the human lineage.";
RL   Nature 440:1045-1049(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000463371}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (AUG-2012) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU361206};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU361206}.
CC   -!- SIMILARITY: Belongs to the TVP23 family.
CC       {ECO:0000256|RuleBase:RU361206}.
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DR   EMBL; AC005517; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC005838; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; J3QL47; -.
DR   jPOST; J3QL47; -.
DR   MaxQB; J3QL47; -.
DR   PeptideAtlas; J3QL47; -.
DR   PRIDE; J3QL47; -.
DR   Ensembl; ENST00000584811; ENSP00000463371; ENSG00000175106.
DR   UCSC; uc060bmd.1; human.
DR   EuPathDB; HostDB:ENSG00000175106.16; -.
DR   HGNC; HGNC:30453; TVP23C.
DR   OpenTargets; ENSG00000175106; -.
DR   eggNOG; KOG3195; Eukaryota.
DR   eggNOG; ENOG4111GAN; LUCA.
DR   GeneTree; ENSGT00390000004428; -.
DR   Proteomes; UP000005640; Chromosome 17.
DR   Bgee; ENSG00000175106; Expressed in 120 organ(s), highest expression level in adrenal tissue.
DR   ExpressionAtlas; J3QL47; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR008564; TVP23-like.
DR   PANTHER; PTHR13019; PTHR13019; 1.
DR   Pfam; PF05832; DUF846; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|RuleBase:RU361206};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|RuleBase:RU361206};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361206}.
FT   SIGNAL        1     20       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        21    141       Golgi apparatus membrane protein TVP23
FT                                homolog. {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003776440.
FT   TRANSMEM     62     83       Helical. {ECO:0000256|RuleBase:RU361206}.
FT   TRANSMEM     89    108       Helical. {ECO:0000256|RuleBase:RU361206}.
SQ   SEQUENCE   141 AA;  16205 MW;  07249A737C7E5F2F CRC64;
     MVTIILLLSC DFWAVKNVTG RLMVGLRWWN HIDEDGKSHW VFESRKESSQ ENKTVSEAES
     RIFWLGLIAC SVLWVIFAFS ALFSFTVKWL AVVIMGVVLQ GANLYGYIRC KVRSRKHLTS
     MATSYFGKQF LRQNTGDDQT S
//