ID   J3QL19_HUMAN            Unreviewed;       127 AA.
AC   J3QL19;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   12-SEP-2018, entry version 36.
DE   SubName: Full=CD226 antigen {ECO:0000313|Ensembl:ENSP00000463335};
DE   Flags: Fragment;
GN   Name=CD226 {ECO:0000313|Ensembl:ENSP00000463335};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000463335, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000463335, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16177791; DOI=10.1038/nature03983;
RA   Nusbaum C., Zody M.C., Borowsky M.L., Kamal M., Kodira C.D.,
RA   Taylor T.D., Whittaker C.A., Chang J.L., Cuomo C.A., Dewar K.,
RA   FitzGerald M.G., Yang X., Abouelleil A., Allen N.R., Anderson S.,
RA   Bloom T., Bugalter B., Butler J., Cook A., DeCaprio D., Engels R.,
RA   Garber M., Gnirke A., Hafez N., Hall J.L., Norman C.H., Itoh T.,
RA   Jaffe D.B., Kuroki Y., Lehoczky J., Lui A., Macdonald P., Mauceli E.,
RA   Mikkelsen T.S., Naylor J.W., Nicol R., Nguyen C., Noguchi H.,
RA   O'Leary S.B., O'Neill K., Piqani B., Smith C.L., Talamas J.A.,
RA   Topham K., Totoki Y., Toyoda A., Wain H.M., Young S.K., Zeng Q.,
RA   Zimmer A.R., Fujiyama A., Hattori M., Birren B.W., Sakaki Y.,
RA   Lander E.S.;
RT   "DNA sequence and analysis of human chromosome 18.";
RL   Nature 437:551-555(2005).
RN   [2] {ECO:0000313|Ensembl:ENSP00000463335}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (AUG-2012) to UniProtKB.
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DR   EMBL; AC011930; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC090231; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC091137; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; J3QL19; -.
DR   PeptideAtlas; J3QL19; -.
DR   PRIDE; J3QL19; -.
DR   Ensembl; ENST00000580335; ENSP00000463335; ENSG00000150637.
DR   UCSC; uc060pzi.1; human.
DR   EuPathDB; HostDB:ENSG00000150637.8; -.
DR   HGNC; HGNC:16961; CD226.
DR   OpenTargets; ENSG00000150637; -.
DR   eggNOG; ENOG410IDXC; Eukaryota.
DR   eggNOG; ENOG41129MS; LUCA.
DR   GeneTree; ENSGT00500000044993; -.
DR   ChiTaRS; CD226; human.
DR   Proteomes; UP000005640; Chromosome 18.
DR   Bgee; ENSG00000150637; Expressed in 108 organ(s), highest expression level in leukocyte.
DR   ExpressionAtlas; J3QL19; baseline and differential.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:J3QL19,
KW   ECO:0000213|PeptideAtlas:J3QL19};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     18       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        19    127       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003777132.
FT   DOMAIN        4    110       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   NON_TER     127    127       {ECO:0000313|Ensembl:ENSP00000463335}.
SQ   SEQUENCE   127 AA;  14638 MW;  3A932A314D50CD17 CRC64;
     MDYPTLLLAL LHVYRALCEE VLWHTSVPFA ENMSLECVYP SMGILTQVEW FKIGTQQDSI
     AIFSPTHGMV IRKPYAERVY FLNSTMASNN MTLFFRNASE DDVGYYSCSL YTYPQGTWQK
     VIQVVQS
//