ID   J3KSF6_HUMAN            Unreviewed;       218 AA.
AC   J3KSF6;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   12-SEP-2018, entry version 35.
DE   SubName: Full=Zona pellucida-binding protein 2 {ECO:0000313|Ensembl:ENSP00000462463};
DE   Flags: Fragment;
GN   Name=ZPBP2 {ECO:0000313|Ensembl:ENSP00000462463};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000462463, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000462463, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16625196; DOI=10.1038/nature04689;
RA   Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA   Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA   Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA   Chang J.L., Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA   DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R.,
RA   Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N.,
RA   Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B.,
RA   Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J.,
RA   Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E.,
RA   Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J.,
RA   Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C.,
RA   Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA   Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA   Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT   "DNA sequence of human chromosome 17 and analysis of rearrangement in
RT   the human lineage.";
RL   Nature 440:1045-1049(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000462463}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (AUG-2012) to UniProtKB.
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DR   EMBL; AC090844; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; J3KSF6; -.
DR   PeptideAtlas; J3KSF6; -.
DR   PRIDE; J3KSF6; -.
DR   Ensembl; ENST00000583811; ENSP00000462463; ENSG00000186075.
DR   UCSC; uc060euc.1; human.
DR   EuPathDB; HostDB:ENSG00000186075.12; -.
DR   HGNC; HGNC:20678; ZPBP2.
DR   OpenTargets; ENSG00000186075; -.
DR   eggNOG; ENOG410IHHK; Eukaryota.
DR   eggNOG; ENOG410YFNT; LUCA.
DR   GeneTree; ENSGT00520000055647; -.
DR   Proteomes; UP000005640; Chromosome 17.
DR   Bgee; ENSG00000186075; Expressed in 30 organ(s), highest expression level in sperm.
DR   ExpressionAtlas; J3KSF6; baseline and differential.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; IEA:InterPro.
DR   InterPro; IPR010857; Sp38-bd.
DR   PANTHER; PTHR15443; PTHR15443; 1.
DR   Pfam; PF07354; Sp38; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:J3KSF6};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     20       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        21    218       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003772091.
FT   NON_TER     218    218       {ECO:0000313|Ensembl:ENSP00000462463}.
SQ   SEQUENCE   218 AA;  24731 MW;  9CBC953457A2E31F CRC64;
     MMRTCVLLSA VLWCLTGAYR EPDYSYQMAV RFTTRSCIGR YNDVFFRVLK KILDSLISDL
     SCHVIEPSYK CHSVEIPEHG LIHELFIAFQ VNPFAPGWKG ACNGSVDCED TTNHNILQAR
     DRIEDFFRSQ AYIFYHNFNK TLPAMHFVDH SLQVVRLDSC RPGFGKNERL HSNCASCCVV
     CSPATFSPDV NVTCQTCVSV LTYGAKSCPQ TSNKNQQY
//