ID   J3KS52_HUMAN            Unreviewed;       305 AA.
AC   J3KS52;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   16-JAN-2019, entry version 50.
DE   SubName: Full=CMRF35-like molecule 1 {ECO:0000313|Ensembl:ENSP00000462309};
GN   Name=CD300LF {ECO:0000313|Ensembl:ENSP00000462309};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000462309, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000462309, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16625196; DOI=10.1038/nature04689;
RA   Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA   Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA   Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA   Chang J.L., Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA   DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R.,
RA   Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N.,
RA   Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B.,
RA   Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J.,
RA   Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E.,
RA   Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J.,
RA   Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C.,
RA   Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA   Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA   Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT   "DNA sequence of human chromosome 17 and analysis of rearrangement in
RT   the human lineage.";
RL   Nature 440:1045-1049(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000462309}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (AUG-2012) to UniProtKB.
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DR   EMBL; AC016888; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_001276013.1; NM_001289084.1.
DR   UniGene; Hs.567706; -.
DR   ProteinModelPortal; J3KS52; -.
DR   PRIDE; J3KS52; -.
DR   Ensembl; ENST00000583937; ENSP00000462309; ENSG00000186074.
DR   GeneID; 146722; -.
DR   UCSC; uc010wra.4; human.
DR   CTD; 146722; -.
DR   EuPathDB; HostDB:ENSG00000186074.18; -.
DR   HGNC; HGNC:29883; CD300LF.
DR   OpenTargets; ENSG00000186074; -.
DR   eggNOG; ENOG410IZ4I; Eukaryota.
DR   eggNOG; ENOG410YT8T; LUCA.
DR   GeneTree; ENSGT00940000154332; -.
DR   OMA; DQEPTYS; -.
DR   OrthoDB; 1494510at2759; -.
DR   GenomeRNAi; 146722; -.
DR   Proteomes; UP000005640; Chromosome 17.
DR   Bgee; ENSG00000186074; Expressed in 116 organ(s), highest expression level in blood.
DR   ExpressionAtlas; J3KS52; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|MaxQB:J3KS52,
KW   ECO:0000213|PeptideAtlas:J3KS52};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     17       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        18    305       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003771674.
FT   TRANSMEM    172    193       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN        2    126       Ig-like. {ECO:0000259|PROSITE:PS50835}.
SQ   SEQUENCE   305 AA;  33798 MW;  D8C7F5321D766673 CRC64;
     MPLLTLYLLL FWLSGYSIVT QITGPTTVNG LERGSLTVQC VYRSGWETYL KWWCRGAIWR
     DCKILVKTSG SEQEVKRDRV SIKDNQKNRT FTVTMEDLMK TDADTYWCGI EKTGNDLGVT
     VQVTIDPAST PAPTTPTSTT FTAPVTQEET SSSPTLTGHH LDNRHKLLKL SVLLPLIFTI
     LLLLLVAASL LAWRMMKYQQ KAAGMSPEQV LQPLEGDLCY ADLTLQLAGT SPQKATTKLS
     SAQVDQVEVE YVTMASLPKE DISYASLTLG AEDQEPTYCN MGHLSSHLPG RGPEEPTEYS
     TISRP
//