ID   J3KQP4_HUMAN            Unreviewed;       251 AA.
AC   J3KQP4;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   16-JAN-2019, entry version 38.
DE   SubName: Full=Folate receptor beta {ECO:0000313|Ensembl:ENSP00000405638};
GN   Name=FOLR2 {ECO:0000313|Ensembl:ENSP00000405638};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000405638, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000405638, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000405638}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (AUG-2012) to UniProtKB.
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DR   EMBL; AP000593; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF455414; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; J3KQP4; -.
DR   SMR; J3KQP4; -.
DR   jPOST; J3KQP4; -.
DR   MaxQB; J3KQP4; -.
DR   PeptideAtlas; J3KQP4; -.
DR   PRIDE; J3KQP4; -.
DR   Ensembl; ENST00000449475; ENSP00000405638; ENSG00000165457.
DR   UCSC; uc058ezy.1; human.
DR   EuPathDB; HostDB:ENSG00000165457.13; -.
DR   HGNC; HGNC:3793; FOLR2.
DR   OpenTargets; ENSG00000165457; -.
DR   GeneTree; ENSGT00940000153758; -.
DR   ChiTaRS; FOLR2; human.
DR   Proteomes; UP000005640; Chromosome 11.
DR   Bgee; ENSG00000165457; Expressed in 215 organ(s), highest expression level in esophagus.
DR   ExpressionAtlas; J3KQP4; baseline and differential.
DR   GO; GO:0005542; F:folic acid binding; IEA:InterPro.
DR   GO; GO:0061714; F:folic acid receptor activity; IEA:InterPro.
DR   GO; GO:1904447; P:folate import across plasma membrane; IEA:InterPro.
DR   InterPro; IPR004269; Folate_rcpt.
DR   InterPro; IPR018143; Folate_rcpt-like.
DR   InterPro; IPR032937; FOLR2.
DR   PANTHER; PTHR10517; PTHR10517; 2.
DR   PANTHER; PTHR10517:SF8; PTHR10517:SF8; 2.
DR   Pfam; PF03024; Folate_rec; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:J3KQP4,
KW   ECO:0000213|PeptideAtlas:J3KQP4};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     38       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        39    251       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003771943.
FT   DOMAIN       47    201       Folate_rec. {ECO:0000259|Pfam:PF03024}.
SQ   SEQUENCE   251 AA;  28919 MW;  65D8EE5DDB1A672C CRC64;
     MLPAATEVQL RLQGQKDMVW KWMPLLLLLV CVATMCSAQD RTDLLNVCMD AKHHKTKPGP
     EDKLHDQCSP WKKNACCTAS TSQELHKDTS RLYNFNWDHC GKMEPACKRH FIQDTCLYEC
     SPNLGPWIQQ VNQSWRKERF LDVPLCKEDC QRWWEDCHTS HTCKSNWHRG WDWTSAALCE
     GLWSHSYKVS NYSRGSGRCI QMWFDSAQGN PNEEVARFYA AAMHVNAGEM LHGTGGLLLS
     LALMLQLWLL G
//