ID   I3L4T9_HUMAN            Unreviewed;       182 AA.
AC   I3L4T9;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   11-JUL-2012, sequence version 1.
DT   16-JAN-2019, entry version 48.
DE   SubName: Full=U3 small nucleolar RNA-associated protein 4 homolog {ECO:0000313|Ensembl:ENSP00000461517};
DE   Flags: Fragment;
GN   Name=UTP4 {ECO:0000313|Ensembl:ENSP00000461517};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000461517, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000461517, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15616553; DOI=10.1038/nature03187;
RA   Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X.,
RA   Xie G., Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A.,
RA   Bajorek E., Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J.,
RA   Buckingham J.M., Callen D.F., Campbell C.S., Campbell M.L.,
RA   Campbell E.W., Caoile C., Challacombe J.F., Chasteen L.A.,
RA   Chertkov O., Chi H.C., Christensen M., Clark L.M., Cohn J.D.,
RA   Denys M., Detter J.C., Dickson M., Dimitrijevic-Bussod M., Escobar J.,
RA   Fawcett J.J., Flowers D., Fotopulos D., Glavina T., Gomez M.,
RA   Gonzales E., Goodstein D., Goodwin L.A., Grady D.L., Grigoriev I.,
RA   Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E., Huang W.,
RA   Israni S., Jett J., Jewett P.B., Kadner K., Kimball H., Kobayashi A.,
RA   Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y., Lowry S.,
RA   Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J.,
RA   Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D.,
RA   Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L.,
RA   Rash S., Retterer J., Ricke D.O., Robinson D.L., Rodriguez A.,
RA   Salamov A., Saunders E.H., Scott D., Shough T., Stallings R.L.,
RA   Stalvey M., Sutherland R.D., Tapia R., Tesmer J.G., Thayer N.,
RA   Thompson L.S., Tice H., Torney D.C., Tran-Gyamfi M., Tsai M.,
RA   Ulanovsky L.E., Ustaszewska A., Vo N., White P.S., Williams A.L.,
RA   Wills P.L., Wu J.-R., Wu K., Yang J., DeJong P., Bruce D.,
RA   Doggett N.A., Deaven L., Schmutz J., Grimwood J., Richardson P.,
RA   Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M., Myers R.M.,
RA   Rubin E.M., Pennacchio L.A.;
RT   "The sequence and analysis of duplication-rich human chromosome 16.";
RL   Nature 432:988-994(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000461517}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (MAY-2012) to UniProtKB.
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DR   EMBL; AC009027; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC009131; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC026474; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; I3L4T9; -.
DR   jPOST; I3L4T9; -.
DR   MaxQB; I3L4T9; -.
DR   PeptideAtlas; I3L4T9; -.
DR   PRIDE; I3L4T9; -.
DR   Ensembl; ENST00000563299; ENSP00000461517; ENSG00000141076.
DR   UCSC; uc059wji.1; human.
DR   EuPathDB; HostDB:ENSG00000141076.17; -.
DR   HGNC; HGNC:1983; UTP4.
DR   OpenTargets; ENSG00000141076; -.
DR   eggNOG; KOG2048; Eukaryota.
DR   eggNOG; ENOG410XQNR; LUCA.
DR   GeneTree; ENSGT00940000153533; -.
DR   ChiTaRS; UTP4; human.
DR   Proteomes; UP000005640; Chromosome 16.
DR   Bgee; ENSG00000141076; Expressed in 198 organ(s), highest expression level in kidney epithelium.
DR   ExpressionAtlas; I3L4T9; baseline and differential.
DR   GO; GO:0001650; C:fibrillar center; IDA:HPA.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR017986; WD40_repeat_dom.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF00400; WD40; 2.
DR   SMART; SM00320; WD40; 4.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|EPD:I3L4T9,
KW   ECO:0000213|MaxQB:I3L4T9, ECO:0000213|PeptideAtlas:I3L4T9};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT   SIGNAL        1     23       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        24    182       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003675273.
FT   DOMAIN       23    182       WD_REPEATS_REGION.
FT                                {ECO:0000259|PROSITE:PS50294}.
FT   NON_TER     182    182       {ECO:0000313|Ensembl:ENSP00000461517}.
SQ   SEQUENCE   182 AA;  20126 MW;  83F0ADF2843ACAD8 CRC64;
     MASVDLSYCS FLHLLLLCSP ILACPPLNGI RCVAYNNQSN RLAVSRTDGT VEIYNLSANY
     FQEKFFPGHE SRATEALCWA EGQRLFSAGL NGEIMEYDLQ ALNIKYAMDA FGGPIWSMAA
     SPSGSQLLVG CEDGSVKLFQ ITPDKIQFER NFDRQKSRIL SLSWHPSGTH IAAGSIDYIS
     VF
//