ID   I3L3Y3_HUMAN            Unreviewed;       150 AA.
AC   I3L3Y3;
DT   11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT   11-JUL-2012, sequence version 1.
DT   12-SEP-2018, entry version 33.
DE   RecName: Full=Golgi apparatus membrane protein TVP23 homolog {ECO:0000256|RuleBase:RU361206};
DE   Flags: Fragment;
GN   Name=TVP23A {ECO:0000313|Ensembl:ENSP00000460822};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000460822, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000460822, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15616553; DOI=10.1038/nature03187;
RA   Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X.,
RA   Xie G., Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A.,
RA   Bajorek E., Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J.,
RA   Buckingham J.M., Callen D.F., Campbell C.S., Campbell M.L.,
RA   Campbell E.W., Caoile C., Challacombe J.F., Chasteen L.A.,
RA   Chertkov O., Chi H.C., Christensen M., Clark L.M., Cohn J.D.,
RA   Denys M., Detter J.C., Dickson M., Dimitrijevic-Bussod M., Escobar J.,
RA   Fawcett J.J., Flowers D., Fotopulos D., Glavina T., Gomez M.,
RA   Gonzales E., Goodstein D., Goodwin L.A., Grady D.L., Grigoriev I.,
RA   Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E., Huang W.,
RA   Israni S., Jett J., Jewett P.B., Kadner K., Kimball H., Kobayashi A.,
RA   Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y., Lowry S.,
RA   Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J.,
RA   Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D.,
RA   Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L.,
RA   Rash S., Retterer J., Ricke D.O., Robinson D.L., Rodriguez A.,
RA   Salamov A., Saunders E.H., Scott D., Shough T., Stallings R.L.,
RA   Stalvey M., Sutherland R.D., Tapia R., Tesmer J.G., Thayer N.,
RA   Thompson L.S., Tice H., Torney D.C., Tran-Gyamfi M., Tsai M.,
RA   Ulanovsky L.E., Ustaszewska A., Vo N., White P.S., Williams A.L.,
RA   Wills P.L., Wu J.-R., Wu K., Yang J., DeJong P., Bruce D.,
RA   Doggett N.A., Deaven L., Schmutz J., Grimwood J., Richardson P.,
RA   Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M., Myers R.M.,
RA   Rubin E.M., Pennacchio L.A.;
RT   "The sequence and analysis of duplication-rich human chromosome 16.";
RL   Nature 432:988-994(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000460822}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (MAY-2012) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU361206};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU361206}.
CC   -!- SIMILARITY: Belongs to the TVP23 family.
CC       {ECO:0000256|RuleBase:RU361206}.
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DR   EMBL; AC074136; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KC877580; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; I3L3Y3; -.
DR   PRIDE; I3L3Y3; -.
DR   Ensembl; ENST00000572428; ENSP00000460822; ENSG00000166676.
DR   UCSC; uc059qte.1; human.
DR   EuPathDB; HostDB:ENSG00000166676.14; -.
DR   HGNC; HGNC:20398; TVP23A.
DR   OpenTargets; ENSG00000166676; -.
DR   eggNOG; KOG3195; Eukaryota.
DR   eggNOG; ENOG4111GAN; LUCA.
DR   GeneTree; ENSGT00390000004428; -.
DR   Proteomes; UP000005640; Chromosome 16.
DR   Bgee; ENSG00000166676; Expressed in 104 organ(s), highest expression level in substantia nigra.
DR   ExpressionAtlas; I3L3Y3; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR008564; TVP23-like.
DR   PANTHER; PTHR13019; PTHR13019; 1.
DR   Pfam; PF05832; DUF846; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|RuleBase:RU361206};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|RuleBase:RU361206};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361206}.
FT   SIGNAL        1     19       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        20    150       Golgi apparatus membrane protein TVP23
FT                                homolog. {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5005684455.
FT   TRANSMEM     60     81       Helical. {ECO:0000256|RuleBase:RU361206}.
FT   TRANSMEM     87    108       Helical. {ECO:0000256|RuleBase:RU361206}.
FT   NON_TER       1      1       {ECO:0000313|Ensembl:ENSP00000460822}.
SQ   SEQUENCE   150 AA;  16818 MW;  3A54D27F4DBADBAC CRC64;
     VMVLLLLSLD FWSVKNVTGR LLVGLRWWNQ IDEDGKSHWI FEARKVSPNS IAATEAEARI
     FWLGLIICPM IWIVFFFSTL FSLKLKWLAL VVAGISLQAA NLYGYILCKM GGNSDIGKVT
     ASFLSQTVFQ TACPGDFQKP GLEGLEIHQH
//